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齐墩果酸

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The Company's most popular product is its Xin Ao Xing Oleanolic Acid Capsule, an over-the-counter medicine for Chronic hepatitis B, a disease affecting approximately 10% of the Chinese population.

公司最受青睐的产品是治疗慢性乙肝的非处方药品——新奥星齐墩果酸胶囊。在中国,慢性乙肝困扰着大约1.3亿人口。

ObjectiveTo develop a new method for simultaneous determination of ursolic acid and oleanolic acid in Prunella vulgaris L.

目的建立同时测定夏枯草中乌索酸及齐墩果酸含量的方法。

Results: Seven compounds were isolated from the ethanol extract of the fruits and identified as oleanolic acid, luteolin-7-O-β-D-glucoside, quercitrin,β-sitosterol-3-O-β-D-glucoside, p-hydroxyphenethyl-β-D-glucoside, D-mannitol and hexitol.

结果:从女贞子的乙醇提取物中分离得到7个单体化合物,分别鉴定为齐墩果酸、木犀草素-7-O-β-D-葡萄糖苷、槲皮苷、β-胡萝卜苷、对羟基苯乙醇-β-D-葡萄糖苷、甘露醇及己六醇。

A new method for determination of oleanolic acid in chinese quince by thin layer chromatography-spectrophotometry was established.

建立测定木瓜中齐墩果酸的薄层色谱-分光光度法的新方法,用薄层色谱分离杂质,优化了分析条件,讨论了影响测定的因素。

A method was developed for the extraction and determination of oleanolic acid from Chinese quince.

本文应用回流提取法、索式提取法、冷浸提取法和超声波提取法对木瓜中的齐墩果酸进行了分离提取,并采用高效液相色谱法测定其含量。

Results: Three compounds were obtained and identified asβ sitosterol, oleanolic acid and rivularicin. Conclusion: Conpound rivularicin were isolated from the plant for the first time.

结果和结论分离并鉴定了该药所含的 3个化合物:①β-谷甾醇、②齐墩果酸、③rivularicin ,其中化合物rivularicin为本实验首次从该植物中分离和鉴定成功。

Compound 9 is glycosylated in the presence of TMSOTf with rhamose-derived trichloroacetimidates to provide target trisaccharide Saponin 1, oleanolic acid 3-yl-2,4-di-O-a-L-rhamnopyranosyl -p-D-glucopyranosideCoumpond 18 is prepared with oleanic acid and Bromide 11 through phase-thansfer catalysis glycosylation manner.

三糖皂苷Saponin 1是以葡萄糖齐墩果酸皂苷为起始原料,用BBTZ(1-苯甲酰苯并噻唑)选择性保护葡萄糖3′,6′-羟基得到化合物9,然后以化合物9为糖基受体,进行一步糖苷化可以在化合物9的2′,4′-羟基上同时引入两分子鼠李糖,最后脱掉所有的保护基得到目标化合物Saponin1。

Results The linear relationship of oleanolic acid was better between 2.77μg~13.85μg, average recovery rate was 97% and the content of total saponin of Achyranthes was 80%.

结果 齐墩果酸在2.77 μg~13.85 μg范围内线性关系良好,平均加样回收率为97.0%,牛膝提取物中总皂苷含量为80。%。

Objective To establish a method for determination of oleanolic acid in Cortex Aralia Elatae by HPLC.

目的 建立HPLC法测定龙芽楤木药材中齐墩果酸的含量测定方法。

Objective: To study the methods for assay of oleanolic acid in root cortex of Aralia taibaiensis.

目的:研究太白楤木根皮中齐墩果酸的含量测定方法。

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