鼻肉

The T cells in nasal polyps express high CD69 and are activated, producing Th1/Th2 mixed cytokines with change of cytokine secretion predomination, probably owing to the formation of microenvironment of the nasal polyps and the mucosa immune system.

鼻息肉组织中的T细胞高度表达CD69分子，处于免疫活化状态，产生Th1/Th2混合模式的细胞因子，与外周血相比Th细胞因子分泌优势发生改变，可能与鼻息肉"微环境"形成及黏膜免疫系统有关。

AIM: To study the effect of Botulinum toxinA on inhibition of rhinorrhea, expression and morphological change of Vasoactive intestinal polypeptide at nasal mucosa, in allergic rhinitis rats.

目的：确定A型肉毒毒素对大鼠变应性鼻炎鼻溢是否具有治疗的作用，以及毒素使用前后血管活性肠肽免疫表达和组织学改变。

Sovereign – a small wart visible at the base of the nose – and closes with a 1702 portrait by Hyacinthe Rigaud, the exalted royal shown in his twilight years and dressed in afantastical blue coronation robe.

展览以济安·洛伦佐·贝尼尼为这位年轻君主雕刻的一尊完美的大理石胸像作为开场（在雕像的鼻根处可以看到一个小小的肉赘），以 1702 年亚森特·里戈绘制的肖像结束（画中，这位已入暮年的尊贵君王身上穿着一件怪诞的蓝色加冕长袍）。

The exhibition opens with an idealized marble bust by Gian Lorenzo Bernini of the young sovereign – a small wart visible at the base of the nose – and closes with a 1702 portrait by Hyacinthe Rigaud, the exalted royal shown in his twilight years and dressed in a fantastical blue coronation robe.

展览以济安·洛伦佐·贝尼尼为这位年轻君主雕刻的一尊完美的大理石胸像作为开场（在雕像的鼻根处可以看到一个小小的肉赘），以1702 年亚森特·里戈绘制的肖像结束（画中，这位已入暮年的尊贵君王身上穿着一件怪诞的蓝色加冕长袍）。

She was a Russian-American girl-big and blonde and animal, with swimming brown eyes, a snub fat nose and chin.

她是一位俄裔的美国姑娘，个儿大大的，一头金发，野性子，水汪汪的棕色眼睛，肉团团的狮子鼻，下巴胖胖的。

She was a Russian-American girl-big and blonde and animal, with swimming brown eyes, a snub f at nose and chin .

她是一位俄裔的美国姑娘，个儿大大的，一头金发，野性子，水汪汪的棕色眼睛，肉团团的狮子鼻，下巴胖胖的。

Objective To study the possibility and significance of reservation of the middle turbinate in endoscopic sinus surgery for sinusitis and/or nasal polyps.

目的 探讨鼻窦炎和/或鼻息肉内窥镜鼻窦手术中保留中鼻甲的可能性及其临床意义。

Results: The lesion located in the left choana region and left sphenoidal sinus of this case involved the left pharyngeal mucous space, left infratemporal fossa and its adjacent bone structure. CT showed that the rhinoscleroma in granulomatous stage was a soft mass which was irregular in shape, with a well-defined margin, inhomogeneous density and bone destruction. MRI showed heterogeneous hyperintensity on T1WI and isointensity on T2WI with an intermediate heterogeneous enhancement.

结果：病变起源于左侧后鼻孔及左侧蝶窦区，累及左侧咽粘膜间隙、左侧颞下窝及邻近骨质；结合本病例及文献复习，肉芽肿期鼻硬结病CT表现为不规则软组织肿块，轮廓清楚，密度不均匀，可见骨质破坏，残存骨质呈硬化改变；MRI表现为T1WI高信号T2WI等信号影，信号不均匀，增强后中度不均匀强化。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

Years , and of the normal nasal mucosa from 8 patients (male 4, female 4, aged 22-43 years, mean age 32 years). Resutls showed that the ER+ cells were morphologically plasma positive and nuclear negative and the plasma contained a large number of dark brown monomorphic granules.

结果显示：鼻息肉和慢性炎性鼻粘膜中，含有一种形态独特的雌孕激素受体阳性细胞，该阳性细胞呈圆形或椭圆形，为胞浆阳性，胞核阴性并且胞浆中含有大量的棕褐色颗粒。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新