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By in situ hybridization, 53BP2 mRNA expression is revealed in tumor cell nests of NPC paraffin sections. The strong positive particles localize in the nuclei of tumor cells; but slight positive signals are also found in tissue cells of chronic nasopharyngitis and connective tissue, such as lymphocytes and smooth muscle cells; There are also positive signals in the nuclei of hyperplastic squamous epithelial cells. However, 53BP1 mRNA expression is not found in nuclei of tumor cells, tissues of chronic nasopharyngitis and connective tissue.

原位杂交结果显示,石蜡切片的鼻咽癌癌巢内,可见53BP2的强阳性表达信号,信号呈紫色颗粒状分布于胞核,核仁清晰可见;而在相同条件下,在慢性鼻咽炎组织和癌旁上皮的结缔组织,也可见弱表达信号,如淋巴细胞和平滑肌细胞;在增生的鳞状上皮细胞的核内,可找到强阳性信号。53BP1在鼻咽癌、慢性鼻咽炎组织和癌旁上皮的结缔组织切片上,均无表达信号。

Anterior rhinoscopy revealed a red polypoid mass that bled easily when touched lightly impinging on the septum and upper nasal cavity.

遂在不破坏血管瘤本身的情况下,将下半部之中鼻甲剪断,并切除所附著血管瘤,术中仅有少量的出血。

Objective: Through comprehensive treatment of the loose skin, muscle, lower eyelid septum and protruding orbital fat in the aged, this kind of operation can correct them and meantime correct the sunken deformity of semilunar curve on the area of oculonasal groove and infraorbital marginalis in some patients.

目的:通过对老化和松弛的眼睑皮肤、肌肉、眶隔筋膜的矫正及眶脂膨出的综合处理,达到矫正睑袋膨出畸形、下睑皮肤皱纹、局部臃肿以及部分求医者显现的眼鼻沟区或眶下沟区的下睑半月弧凹陷畸形。

Case 3, uremic patients JIANG Jing Gang, male, 26 years old, Jintang County of Chengdu City in Sichuan Province and Technical Supervision cadres, he is sick of the news center in the "Understanding" magazine in May 2002 on the semimonthly period,"thought his brother Oliver back, tied with his brother ill shore where entangled" The article on that, in their contacts with the patients have been in the General Hospital of Chengdu Military Region of the last two months and more hemodialysis treatment, but returned home service medicine, there has been more than mouth the risk of hemorrhage, relatives of patients with the Center should request that since May 13, 2002 sent by train from Qingdao arrived home patients using onboard eternal secret Chinese medicine, and patients and their families in the village under suspicion, were completed in two days time, so patients with mouth and nose bleeding more than the danger of the stop, not bleeding, it is no longer need to do hemodialysis, and the medical miracle that I am afraid people will only see personally believe.

病例3,尿毒症患者蒋某某,男,26岁,四川省成都市金堂县某局的干部,他患病的消息是本中心在《知音》杂志2002年5月期上半月刊"仗义哥哥苦海回头,苦命弟弟绝症缠身何处有岸"的文章上得知的,在与他们的联系中,患者已经在成都军区总医院治疗血透了二个多月,后来回家服中药,出现了口鼻出血不止的危症,本中心应患者亲属请求,自2002年5月13日派人从青岛乘火车赶到患者家中,用自带的千古秘方中药,在患者及其家人和全村的怀疑下,仅用了2天的时间,就把患者口鼻出血不止的危症止住了,不出血了,也无需再去做血透了,这样的医疗奇迹恐怕只有亲眼所见才会有人相信。

Canards also make it very difficult to apply flaps: normally, extending flaps causes a downward movement of the nose, which is compensated by the tailplane.

鸭翼也很难做成可动式的:正常情况下,多余的翼动会使机鼻产生向下运动,这尾翼上获得了抵消。

Results Experimental group, 36 cases of patients cured, 32 cases of control group; the experimental group post-operative complications occurred in 2 cases, 11 cases of control group Conclusions To retain part of the uncinate process and opening up sinus surgery may be to maximize the retention of the nasal cavity, paranasal sinuses of the physiological function and structure of the integrity of the nasal cavity to be effective in the preservation of protective barriers to reduce the uncinate process behind the nasal cavity and paranasal sinuses by the direct impact of air flow.

对照组行经典的鼻内镜手术。手术后根据主观症状及复查时鼻内镜下局部状态对疗效做综合评价。结果实验组术后治愈36例,对照组32例;实验组术后并发症发生2例,对照组11例。结论保留部分钩突的鼻窦开放术,可最大程度保留鼻腔、鼻窦的生理功能和结构的完整性,可有效地保存鼻腔的保护屏障,减少钩突后方的鼻窦受到鼻腔气流的直接冲击。

Methods:①Make clinical scale of the magnitude of the tongue and the palate to the group of the OSAHS and the normal control②Successive scanning of the upper airway at the states of the normal inspiration and under the Müller action on both normal controls and the OSAHS patients with multi-slice spiral computed tomography. The scope of scanning was from the roof of nasopharynx to the level of hypohyal, bonding multiplate volume reconstruction,using the image workstation to survey the cross section area, sagittal diameter, coronal diameter on the soft tissue thickness in the lateral pharyngealwall and posterior wall of the pharynx, and the postzone of soft palate, uvula palatine ,tongue and epiglottis.

采用高分辨率多排CT(multi-slice spiral computed tomography,MSCT)对正常人和OSAHS患者的上呼吸道分别在平静吸气状态下以及Müller动作下进行连续扫描,扫描范围从鼻咽顶部至舌骨下缘,图象进行三维重建,应用图像工作站测量正常人和OSAHS患者的软腭后区(retropalatal region,RP)、悬雍垂后区(uvula region,UV)、舌后区(retroglossal region,RG)和会厌后区(epiglottal region,EPG)气道横截面积(cross section area,CSA)、矢状径、冠状径、咽侧壁和咽后壁软组织厚度以及舌体大小(包括舌体长度、舌体最宽处的宽度、中纵切面面积,舌背高度)。

Fourteen pathologic conditions were diagnosed with a biopsy: 4 nasopharyngeal carcinomas (0.2%), 1 hypopharyngeal carcinoma (0.05%), 2 metastatic carcinomas of the hypopharynx (0.1%), 1 vocal cord dysplasia (0.05%), 1 interarytenoid leukoplakia (0.05%), 4 cases of lymphoid hyperplasia (0.2%; 1 in the epiglottis, 3 in the nasopharynx), and 1 pharyngitis (0.05%).

有14例经由切片证实的病理诊断:4个鼻咽癌(0.2%),1个下咽癌(0.05%),2个下咽转移癌(0.1%),1个声带异生(0.05%),1个杓状软骨间白斑(0.05%),4个类淋巴增生(0.2%﹔1个在上会厌,3个在鼻咽),及1个咽炎(0.05%)。

At present it is widely accepted that the damages of the nasal turbinate bones and mucus caused by Bordetella bronchiseptica laid the foundation for the invasion toxigenic Pasteurella multocida. The mixture of Bordetella bronchiseptica and toxigenic Pasteurella multocida, together with some other factors, is the main cause of natural AR.

经过多年研究,现在大多数学者认为,支气管败血波氏杆菌能引起一定程度的鼻粘膜和鼻甲骨损害,但这些病变的严重后果是为正常猪鼻腔不能定居的产毒素多杀巴氏杆菌建立感染铺平道路,Bb和T+Pm的混合感染加上非传染因素交织在一起,是在自然条件下临床型AR的发生原因。

Objective: To provide anatomical basis of clinical transnasal endoscopic approach to the vidian canal by endoscopic anatomical study of vidian canal region.

目的:通过鼻内镜下经鼻腔入路对翼管周围区域的解剖学研究,为临床内镜下翼管区域手术提供解剖学基础。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。