鼠毒

The effects, of protection and treatment with, combined Ch, NaF and a trophie were significantly better than that with atropine alone. In isolated phrenic nerve-diaphragm preparation of rat, isolated jejuneal preparation of, guinea pig, and the metabolic experiment of rat liver, the results of the, assay on the rat blood ChE activity indicated that antidotal effect of NaF may be due to the antidese...

大鼠离体膈神经膈肌、豚鼠离体空肠和大鼠肝脏代谢实验及对大鼠全血胆碱酯酶活力测定的结果表明，NaF的抗毒作用可能是由于其对神经肌肉接头和/或神经节中的N受体的抗脱敏作用；而Ch则可能通过其对ChE的保护和/或加速被抑制ChE的复能，阻碍Ach到达M受体部位而发挥作用。

The main regions (405-1 146 nt) in the glyco pro tein gene of 8202,BRV and MRV,isolated from deer,cattle and mouse in China re spectively,of rabies virus was amplified by reverse transcriptase-polymerase ch ain reaction,cloned and sequenced.

对来源于鹿、牛和鼠的狂犬病病毒野毒株82 02、BRV、MRV的G基因405～1 146位核苷酸序列进行了RT-PCR扩增、克隆和序列测定，并应用计算机软件对这3个毒株的测定序列和人源株CGX89的相应序列进行了分析比较。

In order to verify nicotine effect to heart of rat , analyzing the electrograph Based on these results , it was demonstrated that nicotine can induce to release acetylcholine locally or act on muscarinic cholinoreceptor controlled by parasympathetic nerve .

为进一步确定烟碱对大鼠心脏的作用，对描记烟碱作用后大鼠心电图进行分析，发现烟碱能引起大鼠心电图显示较长的QT间期，增加了PR间期及T波面积，与肾上腺素或去甲肾上腺素引起的QT间期延长相似，且能被M受体阻断剂阿托品所阻断，说明烟碱能够诱导局部释放乙酰胆碱或者作用于部分副交感神经控制的毒蕈碱受体。

In order to develop a safe and effective immunoadjuvant to enhance the immunity and resistance of animals against infection, a novel CpG Oligodeoxynucleotides containing 11 CpG motifs was synthesized and inserted into the VR1012 plasmid, designated as VR1C. Then the recombinant VR1C was entrapped with Chitosan nanoparticles prepared by the method of ionic cross linkage, and employed to inject muscularly 3-weeks old Kunming mice; the blank VR1012 packed with CNP and saline were used to inoculate mice as the control groups. 28 days after inoculation, all mice were orally fed with 0.4ml 2x108CFU/ per mouse virulent hemorrhagic enteritis E. coli to challenge the resistance against infection.

为研制安全高效免疫调节剂增强动物免疫抗病能力，本实验设计合成含11个C pG基序的寡聚核苷酸，重组构建含CpG的VR1012质粒(VR1C)；制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C)，肌注接种3周龄昆明小白鼠，设壳聚糖包裹空质粒和生理盐水对照组；接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力，Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。

AIM: To investigate the antinociceptive effect of anticholinesterase agent physostigmine at different postoperative time, and the interaction of intravenous physostigmine with intrathecal morphine in rats.

目的：观察在术后不同阶段静脉注射胆碱酯酶抑制剂毒扁豆碱对鼠痛阈的影响，以及静注毒扁豆碱和蛛网膜下腔注射吗啡的药物相互作用。

BmK IT2 is worthy of being considered to be a kind of new algesia peptide drug.

BmK粗毒和BmK I诱导的大鼠脊髓背角氨基酸类神经递质的释放采用微透析采样与高效液相色谱荧光检测技术，分析BmK粗毒和其主要致死成分BmK I诱发炎症痛过程中同侧脊髓背角氨基酸含量的动态变化。

The local injection of trypsin can be used in clinical practice as a new and effective therapy for snakebite.Our experiments indicate that when a lethal dose of crotalinae snake venom was injected into mice subcutaneously, survival rate increased significantly if a dose of trypin had been injected locally and promptly.

本文提供了一种局部注射胰蛋白酶治疗蛇伤的方法，在给小白鼠皮下注射致死剂量的竹叶青蛇毒后，立即注射胰蛋白酶可提高存活率68％，注射蝮蛇毒后，立即注射胰蛋白酶可提高存活率67％，注射尖吻蝮蛇毒后立即注射胰蛋白酶可提高存活率57％。

Endplate potentials, acetylcholine potentials, and electrotonic potentials were recorded from the motor endplates of isolated diaphragms from acute late septic and nonseptic rats.

记录急性迟发性脓毒血症和非脓毒血症大鼠的离体横膈运动终板上的终板电位、酰胆碱电位和电紧张电位。

In view of the host critical mouse—Ochotona curzoniae in the western-north Sichuan plateau, applicated experiment in the big area was taked, using racin as the main componet.

针对川西北高原的主要害鼠—高原鼠兔，应用蓖麻毒素灭鼠剂进行了野外防治实验，在大面积实验中，该粗毒以1％浓度配制毒饵对高原鼠兔的校正灭效为85％以上。

The nucleotides sequence and deduced amino acid sequence of these cDNA figments mentioned above were divided into two fractions. One is carbon part of L gene , the other is 5 terminal,and they were compared with other rabies-related virus strains published in NCBI previously.The result show that the homology of nucleotide sequence and amino acid sequence of carbon part in L gene among these two rabies virus strains is 91.3% and 95.8%, and these two strains belong to type of gene I.

本实验以吉林鹿源DRV8202株及河南鼠源野毒株MRV的L基因的C端为主要研究内容，用RT-PCR和3'-RACE方法对其进行了克隆和测序，将所测得的核苷酸序列和推导的氨基酸序列分成两个部分，一是L基因C端序列，另一个是L基因5'端的非编码区，并与NCBI上公开发表的狂犬病毒其它毒株的相应片段进行分析比较。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。