鼠毒

In this study, the DNA fragments coding for amino acids 133～158 of VP1and 20～34 of VP4protein of type Asial FMDV were chemically synthesized and ligated into a tandem repeat 133～158-20～34-133～158. The sequences of signal peptide of Igκ chain and Kozak were fused to the 5'end of this tandem sequence and synthetic oligodeoxynucleotide containing CpG-ISS was fused to downstream of terminal coden of this tandem sequence. And then this long fragment was cloned into the eukaryotic expression plasmid pHook-2, forming a new secreted expression plasmid, named pAS1-E.

在第二章证明了亚洲Ⅰ型口蹄疫病毒VP1蛋白中133～158位氨基酸残基确是一重要B细胞中和抗原表位的基础上，依据第一章获得的口蹄疫病毒亚洲Ⅰ型VP1 cDNA序列及已报道Asial VP4序列，采用真核偏爱密码子化学合成了VP1中编码133～158位氨基酸及VP4中编码20～34位氨基酸这两个抗原表位基因，将其组成133～158-20～34-133～158串联结构，在其5′端加上鼠Igκ链信号肽序列，在翻译调节区加上增强表达的Kozak序列，同时在133～158-20～34-133～158串联结构3'端终止密码子下游加上CpG免疫刺激序列，将这些片段连接后，克隆到真核表达载体pHook-2上，构建成功了DNA疫苗重组表达载体pAS1-E。

objective: to investigate the relation of tumor necrosing foctor α and hepatis apoptosis and the effect of liver function in sepsis.

目的：探讨脓毒症大鼠肿瘤坏死因子 a与肝细胞凋亡的关系以及对肝功能的影响。

Zhuang prohibited in some areas will blast out into the village of pork, or dead cat, rat, snake and chicken feathers discarded objects such as dirty in the village, for fear of infuriating the gods and infectious diseases, specifically built for this purpose a number of villages have "lost virulence village ", to address this dirty thing.

一些地方的壮族禁止将瘟猪肉挑进村子，或是将死猫、鼠、蛇及鸡毛等污秽之物丢弃于村，怕惹怒神灵和传染疾病，为此一些村寨专门建有&丢毒村&，以处理上述污秽之物。

Objective: To investigate the effect of arterial baroreflex on survival rate of rats with cecal ligation and puncture-induced sepsis.

目的：观察动脉压力感受性反射对盲肠结扎穿孔致脓毒症大鼠生存率的影响。

Methods Sepsis was produced in rats by cecal ligation and puncture.

采用盲肠结扎穿孔术建立SD大鼠脓毒症模型。

Objective:To study the effects of Liangxuehuoxue Formula on the the expression of multiple adhesion molecules in treating a cecal ligation and puncture rat septic model.

中文摘要：目的：研究凉血活血方对脓毒症大鼠白细胞黏附分子表达的影响，探讨其药理作用机制。

In addition, only certain murine mAb isotypes have been shown to effectively bind to and activate elements of the human immune system, thereby triggering cytotoxic effector functions.

另外需说明的是，只有特定的几种鼠源同种型单抗显示出有效结合并激活人类免疫系统，激活细胞毒作用的能力。

Objective To explore the toxic effects and mechanism of methyl tertiary-butyl ether in the brain tissues of fetal mice and pregnant mice.

目的：探讨甲基叔丁基醚(Methyl Tertiary Butyl Ether， MTBE)对孕鼠及其胎鼠脑组织的毒作用及分子机制。

Objective To investigate the effects of methyl tertiary butyl ether on the FOS protein in central nervous system of the rats. Methods 54 SD healthy adult-rats weighed 180~220g were involved in this study.

目的 通过研究甲基叔丁基醚对大鼠中枢神经系统Fos蛋白的影响，探讨MTBE对中枢神经系统急性毒作用部位。

The technique of liver CYP450 enzymes was applied to the in vitro study of drug metabolism In the first part of this article, the metabolism of nimodipine in human liver microsomes was studied and in the second of part of this article the metabolism of clivorine in female rat, guinea pig, human liver microsomes as well as the mechanism of metabolism-induced toxicity were investigated.

运用肝微粒体技术进行药物的体外代谢研究。本论文第一部分运用肝微粒体技术研究了尼莫地平在人肝微粒体内的代谢及其代谢的酶动力学，第二部分研究了肝毒性生物碱Clivorine在大鼠、豚鼠和人肝微粒体内的代谢及其代谢致毒机理。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。