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鼠李皮

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A buckthorn native to northwest North America, the bark of which is the source of cascara sagrada.

药鼠李树原产北美洲西北部的一种药鼠李树,其树皮是药鼠李皮剂的原料

Shrubby tree of United States Pacific coast; yields cascara sagrada.

美国太平洋海岸的一种灌木状树木;生产鼠李皮

These drugs include atropine, belladonna, cascara , castor oil, cocaine, curare, ephedrine, morphine, opium, and senna.

这些药物有:阿托品,颠茄,波西鼠李皮,海狸香油,可卡因,箭毒,麻黄碱,吗啡,鸦片和番泻叶。

Costive one tabloid of cascara sagrada.

便秘嘛,请服一片药鼠李皮

The oxidation mechanism of synephrine was also investigated;(2) The electrochemical behavior of twelve flavonoids (quercetin, morin, fisetin, luteolin, isorhamnetin, myricetin, hyperoside, quercitrin, puerarin, farrerol, naringenin and hesperidin) was investigated. The method for the determination of flavonoids was developed by using different pulse voltammetry, and the detection limit was in the range of 10-7~10-9 mol/L. This method has been successfully employed to determine the total amount of flavonoids in pericarpium citri reticulatae and quercetin in the spiked human blood plasma samples.

2研究了槲皮素、桑色素、漆黄素、木犀草素、异鼠李素、杨梅素、金丝桃甙、槲皮甙、葛根素、杜鹃素、柚皮甙元和橙皮甙等12种黄酮类化合物在玻碳电极上的电化学氧化行为,建立了测定黄酮类化合物的微分脉冲伏安法,检测限可达10~(-7)~10~(-9) mol/L,并用DPV法测定了陈皮中总黄酮含量和模拟血清中的槲皮素,结果较为满意。

Microbial transformation offers new access to gain quercetin and rhamnose.

种新型的槲皮素、鼠李糖生产方法。关键词:微生物转化;芦丁;槲皮素;鼠李糖

Their structures were identified by chemical and spectral analysis. RESULTS Five compounds were isolated and identified as stigmasterol 3-O-β-D-glucopyranoside, 20β-hydroxy-ecdysone,β-L-thymidine, pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside and pennogenin 3-O-α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)-]-β-D-glucopyranoiside.

结果 分离并鉴定了5个化合物,分别是Δ5,22-豆甾醇3-O-β-D-葡萄吡喃糖苷,20β-羟基蜕皮激素,β-L-脱氧胸腺嘧啶苷,偏诺皂苷元3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-葡萄吡喃糖苷和偏诺皂苷元3-O-α-L-鼠李吡喃糖基-(1→4)-α-L-鼠李吡喃糖基-(1→4)-[α-L-鼠李吡喃糖基-(1→2)-]-β-D-葡萄吡喃糖苷。

Quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E wereisolated from the flower of Acanthopanax senticosus. Searching bioactive natural compound and establishing quality evaluation standard arefocused on this experiment. Using cold immersing of 70% methanol to extract from flower ofAcanthopanax senticosus and integrating macroporous resin, silica gel column chromatography,sephadex gel to abstract. We obtained five monomer compounds (compoundⅠ-compoundⅤ),quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E. That five compoundswere determined by HPLC in eight parts of Acanthopanax senticosus (flower, root, leaf fruit,shoot, new shoot, phloem of shoot, skin of shoot), which provide science bases for establishingquality evaluation system and settle infarctate foundation.

本文以从刺五加花蕾中寻找具有重要生物活性的天然化合物和建立质量评价标准为主要目的,对其化学成分进行研究,采用70%甲醇冷浸的方法对刺五加花蕾中的成分进行提取,运用大孔树脂吸附色谱法、硅胶柱层析法以及葡聚糖凝胶柱层析相结合的方法进行分离,得到5种单体化合物,分别为槲皮素、槲皮素鼠李糖苷、金丝桃苷、紫丁香苷和刺五加苷E;利用高效液相色谱法对这5种化合物在刺五加花蕾中的含量进行了测定;考察了8个部位(花蕾、根、叶、果、茎干、新枝、茎韧皮部、茎皮)中这5种化合物的含量分布情况,并作一比较,为今后建立刺五加质量评价体系提供了科学依据,奠定了坚实的基础。

Assaying results indicate that in that eight parts of Acanthopanax senticosus content ofquercetin is highest in leaf,0.03818%, content of quercetin rhamnoside is highest in flower,4.43115%, content of hyperin is highest in flower,2.41605%, content of syringoside is highest inskin of shoot,1.18959%, content of eleutheroside E is highest in root,

含量测定结果表明:在刺五加花蕾、根、叶、果、茎干、新枝、茎韧皮部、茎皮这八个部位中,槲皮素叶中含量最高,为0.03818%;槲皮素鼠李糖苷花蕾中含量最高,为4.43115%;金丝桃苷花蕾中含量最高,为2.41605%;紫丁香苷茎皮中含量最高,为1.18959%;刺五加苷E根中含量最高,为0.18802%。

RhaG hydrolyzed only the 6-C α-rhamnoside of ginsenoside Re, RhaR is able to hydrolyze the α-rhamnoside of rutin、hesperidin and naringin.

实验结果表明,RhaG只水解人参皂苷Re的C-6位末端上的一个α-鼠李糖基,而RhaR能水解芦丁、橙皮苷、柚皮苷的α-鼠李糖基。

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