黑素瘤

Objective To investigate the possible mechanism of curcumin inhibition to murine melanoma growth.

目的 探讨姜黄素抑制小鼠黑素瘤作用的可能机制。

Objective To evaluate the biological effect of endothelin antagonist on cultured B16 murine melanoma cells.

目的 研究天然提取的内皮素拮抗剂对体外培养的B16鼠黑素瘤细胞的生物学作用。

Objective To investigate the expression of cannabinoid receptor 2 （CB2） in pigmented nevus and malignant melanoma and its significance.

目的 探讨大麻素2型受体（CB2受体）在色素痣及皮肤恶性黑素瘤中的表达规律及其意义。

NSE are reported to be useful diagnostic marker for lung cancer, neuroblastoma, melanoma, seminoma and in injury of central nervous system.

据文献报道，NSE含量测定可作为肺癌、成神经细胞瘤、黑素瘤、精原细胞瘤以及中枢精神系统损伤的诊断指标。

Objective To study the effect of traditional Chinese medicine on tyrosinase activity and the melanogenesis of B－ 16 murine melanoma cell.

目的研究复方中药对小鼠B－16黑素瘤细胞株细胞增殖、黑素合成的影响，及其对细胞内酪氨酸酶的激活作用。

Vernonia anthelmintica can significantly enhance the activity of tyrosinase in vitro and proliferation of B-16 murine melanoma cell.

结果驱虫斑鸠菊体外可激活酪氨酸酶活性，增强B - 16鼠黑素瘤细胞增殖，提高酪氨酸酶和黑色素合成能力；对整体动物黑素细胞具有促进合成和分泌作用。结论在白癜风的治疗中，驱虫斑鸠菊可增强酪氨酸酶活性，进而促进黑素合成

Tumour Biol, 1998,19:244-252.［3］ Olson DJ, Gibo DM, Saggers G, et al. Reversion of uroepithelial cell tumorigenesis by the ectopic expression of human wnt5a ［J］.

Bachmann等［12］发现细胞核内Wnt5A基因表达越高，黑素瘤进展越慢，对瘤组织周围的侵袭能力也越弱。

Except for the acral-lentiginous subtype of melanoma, the vast majority occurs in sun-exposed areas.

除肢端雀斑痣样黑素瘤外，大多数黑素瘤出现在阳光照射部位。

Topol L, Jiang X, Choi H, et al. Wnt5a inhibits the canonical Wnt pathway by promoting GSK3 independent catenin degradation ［J］. J Cell Biol, 2003,162:899-908.［2］ Olson DJ, Oshimura M, Otte AP, et al.

Wnt5A基因被认为是评价皮肤黑素瘤侵袭能力的重要指标［10］，并且进一步的研究显示： Wnt5A介导的Wnt/Ca2+信号通路主要通过激活蛋白激酶C增强黑素瘤的侵袭力［11］。

The researchers, both from the Uniersity of Regensburg, found that compared to normal melanocytes, TANGO was lost or downregulated in 9 melanoma cell lines. This was also true of most of 8 human tumor samples, and was associated with adanced tumor stage.

研究者都来自雷根斯堡大学，从最终进展到晚期的8个黑素瘤患者样本中培养得到的9个黑色素瘤细胞株，经过和正常黑素细胞对比研究发现黑色素瘤细胞中TANGO基因丢失或下调。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。