黑瘤

Human melanoma A375 cells express Cox-2 protein and MMP-1 protein. Celecoxib may be a potential chemotherapeutics for the proliferation of melanoma.

人黑素瘤A375细胞表达Cox-2蛋白和MMP-1蛋白，Celecoxib是一种有潜力的抑制黑素瘤增殖的药物。

All but one melanoma was diagnosed in families with two or more first-degree relaties with melanoma.

有两个以上黑素瘤患者一级亲属的家庭中，只有一人被诊断为黑素瘤。

NSE are reported to be useful diagnostic marker for lung cancer, neuroblastoma, melanoma, seminoma and in injury of central nervous system.

据文献报道，NSE含量测定可作为肺癌、成神经细胞瘤、黑素瘤、精原细胞瘤以及中枢精神系统损伤的诊断指标。

Objective To establish human normal melanocytes cell line in vitro and observe the effects of Azelaic acid on the pigment production of the epidermal melanocytes and B16 cells.

目的 建立体外培养的正常人表皮黑素细胞系，检测壬二酸对人表皮黑素细胞和鼠黑素瘤B16细胞黑素合成的影响。

Vernonia anthelmintica can significantly enhance the activity of tyrosinase in vitro and proliferation of B-16 murine melanoma cell.

结果驱虫斑鸠菊体外可激活酪氨酸酶活性，增强B - 16鼠黑素瘤细胞增殖，提高酪氨酸酶和黑色素合成能力；对整体动物黑素细胞具有促进合成和分泌作用。结论在白癜风的治疗中，驱虫斑鸠菊可增强酪氨酸酶活性，进而促进黑素合成

Objective: To determine clinical value of serum melanoma inhibiting activity in patients with malignant melanomas.

目的 ：探讨血清黑素瘤抑制蛋白(melonom a- inhibiting activity protein，MIA)在恶性黑素瘤诊断中的价值。

On their website, they state that people who use sunbeds before the age of 35 have a higher risk of melanoma – the most dangerous type of skin cancer.

在他们的网站，说明了在35岁之前实用美黑床的人有很高患黑素瘤的风险——而黑素瘤是最危险的一种皮肤癌。

Malignant melanoma: Malignant melanoma can occur on any area of the skin or mucosa, even in non–sun-exposed skin, as in this patient.

恶性黑素瘤：恶性黑素瘤可以出现在皮肤或粘膜的任何地方，甚至在非阳光照射部位的皮肤，正如该患者一样。

Except for the acral-lentiginous subtype of melanoma, the vast majority occurs in sun-exposed areas.

除肢端雀斑痣样黑素瘤外，大多数黑素瘤出现在阳光照射部位。

Topol L, Jiang X, Choi H, et al. Wnt5a inhibits the canonical Wnt pathway by promoting GSK3 independent catenin degradation ［J］. J Cell Biol, 2003,162:899-908.［2］ Olson DJ, Oshimura M, Otte AP, et al.

Wnt5A基因被认为是评价皮肤黑素瘤侵袭能力的重要指标［10］，并且进一步的研究显示： Wnt5A介导的Wnt/Ca2+信号通路主要通过激活蛋白激酶C增强黑素瘤的侵袭力［11］。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。