黄连

Objective: To evaluate the effect of additives on absorption of Coptis chinensis total alkaloid and their pharmacokinetics in mice.

中文摘要：目的：筛选促进小鼠吸收黄连总生物碱的助剂，研究黄连总生物碱的药代学。

Hydrastine(97.7%) was obtained with extracted rate 65%by extracting the Goldenseal with mixed Solvent;Berberine hydrochloride (99.9%) was obtained by adding hydrochloride acid to alcohol (alcohol∶H 2O=1∶1) solution of the extract and Hydrastine (99.5%) was gained by CLC method with the yield 1%.

原药材用混合溶剂直接提取分离，可得到含北美黄连碱 97.7%的结晶体，提取率达 6 5%；提取物经醇水溶解、酸化，可直接获得小檗碱盐酸盐结晶，纯度达到 99.9%；用柱色谱法，可得到 99.5%的北美黄连碱，收率约 1

The influence of menstruum on solubility of protoberberinium alkaloids in the couple of Rhizoma Coptidis and Fructus Evodiae

目的：考察黄连与吴茱萸按不同比例配伍时，黄连中主要化学组分溶出率的变化规律。

ResultsThe optimized extraction technology for Huang-lian-xiao-ke Granule was as follows: Copis chinensis Franch. and the other four kinds of raw materials in the origin prescription were decocted separately; after soaked for 30min, the coarse powder of Copis chinensis Franch was decocted with 12,10 times water each time and both for 1.5h; after soaked for 30min, the four kinds of raw materials were decocted together for 1.5h just one time with 10 times water.

结果优选出的提取工艺为：黄连与原方中其余四味药分开提取；黄连粗粉浸泡30 min后，用12，10倍量水提取2次，提取时间均为1.5 h；其余4味药一起提取，浸泡30 min，加10倍量水提取1次，提取时间为1.5 h。

Objective: To study the changes of nutrient contents in Chinese goldthread soil before and after planting Coptis chinensis.

通过对种植黄连土壤营养条件进行研究，为黄连的科学施肥提供依据。

To explore the effects of endogenous plant hormones in the flowers on seed development of Coptis deltoidea C.

探索三角叶黄连和峨眉黄连花的内源性激素对种子形成的影响。

In addition, the output of coptis in Shizhu region accounts for about 60% of the country's total and therefore, the region is called Chinese famous "Hometown of Coptis".

此外，石柱地区的黄连产量占全国年总产量的60%左右，是中国著名的&黄连之乡&。

Objective : To learn the effects of coptis in treating neonatal jaundice and to find the index that guides the clinical administration of the medicine.

中文摘要：目的：了解黄连对新生儿黄疸发病的影响作用，为黄连的安全性用药提供依据。

A viable technical measure could be found to improve the quantity and quality of Coptis chinensis Franch accordingly and form a set for the academic base.

从而，找出可以提高黄连的产量和品质的技术措施，为黄连的优质高产提供理论依据。

Objective:To make clear the influence of Huanglian and berberine on the erythrocytic osmotic fragilitas of glucose-6-phosphate dehydrogenase(G6PD) deficiency in rats,so as to infer whether Huanglian and berberine have medicamentosus hemolysis effects.

中文摘要：目的：了解黄连和小檗碱对G6PD缺陷大鼠红细胞渗透脆性的影响，藉以推断黄连和小檗碱是否存在药物性溶血作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。