黄嘌呤

RNA editase transforms or modifies the nucleotide of pre-RNA by deaminization, and hydrolytic deaminize C6 amino group of the adenosine at the specific RNA site, changing adenosine to inosine or changing cytosine to uracil,but inosine was recognized as guanine in mRNA.

RNA编辑酶以脱氨方式使得RNA特异位点的腺嘌呤脱氨转变为次黄嘌呤，或者是特异位点的胞嘧啶变为尿嘧啶，而次黄嘌呤在碱基配对时被识别为鸟嘌呤。

Object: The purpose of this study was to supply people with scientific dietary instructions by investigating the change of the content of adenine, guanine, xanthine and hypoxanthine in two Huahuang fish and carp during boil processing. Method The HPLC method was accepted.

目的：通过检测经过水煮的黄花鱼和鲤鱼中腺嘌呤、鸟嘌呤、黄嘌呤、次黄嘌呤的含量，探索在高温水煮过程中嘌呤含量的变化，希望以此为人们的健康饮食提供科学的指导基础。

It shows that the allantoin, which only takes little part in calves, was the main part (about73%~88%) in the cattle's urine, and the xanthine and hypoxanthine which are also take only much little part, can be neglected.

结果发现，试验牛尿中嘌呤衍生物中尿囊素大约为73%~88%，黄嘌呤和次黄嘌呤的含量很小，可以忽略不计，与以往对成年反刍动物的研究结果相似，与同个体犊牛期的研究结果相反。

The reactivity of guanine, adenine and hypoxanthine on electrodes made with different materials is discussed. The rough pyrolytic graphite electrode was selected for the electrochem. study.

本文讨论了鸟嘌呤、腺嘌呤和次黄嘌呤等嘌呤类生物小分子在几种电极上的反应活性，并选用粗热解石墨电极研究了它们的电化学性质。

Basal oxypurines (xanthine, hypoxanthine, and urate) rose with FA pretreatment but increased less during ischemia than in controls.

以FA预处理后基础羟基嘌呤(黄嘌呤，次黄嘌呤和尿酸盐)增加了，但缺血组却比对照组增加要少。

The content of purines in soup increased sharply during 10 min, increased slowly during 10 min to 60 min. The content of adenine in carp weighed 200 g increased during boiling process, that of guanine was stable, that of total purines and hypoxanthine decreased. The content of total purines and four purines in Huahuang fish decreased during boil processing.

鱼汤中嘌呤含量在10min内迅速升高，10~60min缓慢升高。200g鲤鱼中腺嘌呤含量在水煮加热过程中升高，鸟嘌呤含量无明显变化，总嘌呤和次黄嘌呤组分含量下降，200g黄花鱼的总嘌呤及4种嘌呤组分含量在水煮加热过程中下降。

A method of screening serum of patients of gout and hyperuricemia includes checking purine compound content of xanthine and hypoxanthine in serum to be tested, confirming that serum to be tested is serum of gout patient if xanthine content of 1.00-2.35 mg / L and / or hypoxanthine content of 4.1-16.00 mg / L are contained in serum to be tested and confirming that serum to be tested is serum of hyperuricemia patient if xanthine content of 0.20-1.20mg/L and / or hypoxanthine content of 1.30-3.50mg/L are contained in serum to be tested.

本发明所提供的筛查痛风疑似患者及高尿酸血症疑似患者血清的方法，是检测待测血清中包括黄嘌呤和次黄嘌呤在内的嘌呤化合物的含量，如待测血清中黄嘌呤含量为1.00-2.35mg/L，和/或次黄嘌呤含量为4.1-16.00mg/L，则待测血清为痛风疑似患者血清；如待测血清中黄嘌呤含量为0.20-1.20mg/L，和/或次黄嘌呤含量为1.30-3.50mg/L，则待测血清为高尿酸血症疑似患者血清。

According to a statement from Takeda, febuxostat is a new highly potent non-purine selective inhibitor of xanthine oxidase, and has a completely different structure from the currently used xanthine oxidase inhibitor, which was developed over 40 years ago.

根据该公司的声明，febuxostat是一种新的非嘌呤类黄嘌呤氧化酶选择性强抑制剂，与40多年前发明并延用至今的黄嘌呤氧化酶抑制剂的结构完全不同。

NADPH oxidase inhibitor, diphenylene iodonium chloride (DPI, 10 μmol/L), abolished histamine-stimulated calcium oscillations both in normoxic and posthypoxic PAECs.(3) Xanthine oxidase inhibitor, oxypurinol (100 μmol/L), did not affect the calcium oscillation kequency in normoxic PAECs. However, it significantly decreased the elevation of calcium oscillation frequency in posthypoxic PAECs.

黄嘌呤氧化酶抑制剂，别嘌呤醇(oxypurinol，100 μmol/L)能显著降低组胺刺激的缺氧后肺动脉内皮细胞升高的钙振荡频率，但降低后的钙振荡频率仍高于常氧组，别嘌呤醇对组胺刺激的常氧组肺动脉内皮细胞钙振荡频率无显著影响。

Comparative studies of electroactive components and voltammetric behaviors different between the MCF-7 cell without estrogen and the MCF-7 cell with estrogen showed that the concentration of the guanine and xanthine bases in the cytoplasm decreased, which resulted in the decrease of secretion ability of the MCF-7 cell without estrogen decreased, and these result in the decreasing of the voltammetric response of the cells, impling that the cell vaibility decreases.

结果发现，去激素MCF-7细胞质中的黄嘌呤和鸟嘌呤浓度降低，使细胞分泌黄嘌呤和鸟嘌呤能力降低，导致细胞和细胞质的伏安信号减弱，说明去激素MCF-7细胞的活性下降；研究了标准雌激素雌二醇、环境雌激素壬基酚和双酚A对去激素培养的MCF-7细胞增殖的影响，发现其均存在剂量-效应关系和时间-效应关系，并且雌激素效应由大到小的顺序为：雌二醇＞壬基酚＞双酚A；同时使用3-(4，5-Dimethylthiazol-2-yl)-2，5-diphenyltetrazolium bromide法验证了电化学法评价雌激素效应的可靠性。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。