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Positive results of mutagenicity have been obtained with chrysophanol aloe-emodin emodin and chrysarobin in Salmonella /microsome assays.

致畸作用。沙门氏菌/微粒体中的致畸结果为阳性的有:大黄酚,芦荟-大黄素,大黄素,和驱虫豆素以上均为大黄的化学成份),大黄酸的结果为阴性。

The expert thinks, corpus luteum of the leaf before iodine can stimulate hypophysis makes element, promote ovarian and follicular corpus luteum to change, make level of the estrogen inside human body is reduced thereby, restore ovarian normal function, correct endocrinopathy, eliminate the hidden danger of mammary gland hyperplasia.

专家认为,碘可以刺激垂体前叶黄体生成素,促进卵巢滤泡黄体化,从而使人体内雌激素水平降低,恢复卵巢的正常机能,纠正内分泌失调,消除乳腺增生的隐患。

We detected that EGF mRNA was expressed sflungly lii the oocyte, and is also found hi gmnulosa cells, the cell fium smaller foflicular expressed stronger than fium bigger one. In the corpus hemonbaglcwn corpus luteurn, lean type and pseudocorpus-luteum, EGF rnRNA was detected,, no distinct difference can be seen in them. The EGF mRNA expressed strongly in fimbria end, ampulla and isthmus of oviduct, in the big follicular stage, ovulation stage, pregnancy stage and spurius pregnancy stage, we can not see any distinct change in them, but hi the medium follicuar stage,it is weaker.

结果发现:猪卵母细胞中EGF的mRNA强烈表达,且小卵泡卵母细胞→中卵泡卵母细胞→大卵泡卵母细胞中,EGF的mRNA表达量有逐渐减少的趋势;猪卵泡的颗粒细胞中有EGF的mRNA表达,小卵泡颗粒细胞→中卵泡颗粒细胞→大卵泡颗粒细胞中,EGF的mRNA表达也有逐渐减少的趋势;猪卵巢中的红体、黄体、白体和假黄体中都有EGF的mRNA表达,看不出几部分的表达量有明显的强弱变化;猪输卵管伞部、壶腹部和峡部,都有EGF的mRNA表达,在大卵泡期,排卵期,孕期和假孕期都强烈表达,各期间看不出明显的强弱变化,中卵泡期表达较弱;猪子宫中EGF的mRNA在大卵泡期,排卵期,孕期和假孕期都强烈表达,看不出表达量的明显变化,而小卵泡期表达量明显减弱。

RESULTS: The findings show that 17beta-estradiol, progesterone, or both hormones administered together significantly influenced the expression of numerous genes in the mouse meibomian gland.

结果:检查所见显示在小鼠睑板腺中,17beta-雌二醇、黄体酮或17beta-雌二醇联合黄体酮注射对于很多基因的表达都有显著影响。

Here is the microscopic apperance of a hemorrhagic corpus luteum lined by luteinized granulosa cells next to the hemorrhagic area at the right.

这是卵巢黄体血肿镜下的形态学改变。可见黄体粒层上皮细胞与右侧的出血区相邻。

OLH or 8-bromo-cAMP were added to luteinized granulosa cells. Results indicated that, protein expression of HIF-1a, HIF-1b and VEGF had a better performance in hypoxia than in normoxic condition, but phospho-PKA, StAR and P450scc protein expression had weaker expression in the former condition than in the later one. As a result of decreasing secretion of progesterone the decreasing of phospho-PKA was suspected to have a role in the reduction of StAR and P450scc in the condition of hypoxia.

结果发现,黄体化粒性细胞於缺氧条件下其HIF-1a、HIF-1b与VEGF蛋白质表现量皆较正常氧高;同时,StAR及P450scc蛋白质表现量则降低,但3b-HSD不受缺氧影响;此外,藉由特异性抗体检测PKA讯息传递路径发现,PKA讯息传递路经於缺氧条件下磷酸化PKA(phospho-protein kinase A)蛋白质表现量下降,可能经此路径的调控造成StAR及P450scc蛋白质表现量下降,导致黄体化粒性细胞孕酮分泌量减少。

The larger one at the top is a hemorrhagic corpus luteum of menstruation, and the smaller one at the bottom is involuting from a previous menstrual period.

在上方较大是月经期出血黄体,在下方较小的是上一次月经退化的黄体。

In this experiment,the different types of corpus luteum and follicular development on cattle ovary through histology method were observes.

本试验通过对牛卵巢不同黄体类型和各级卵泡生长发育状况的组织学观察,探讨了不同黄体类型对各级卵泡生长发育的影响。

The effect of those corpus luteum type on the follicular growth were approached.

试验结果表明:1不同类型黄体之间,黄体功能的强弱不同。

Corpus luteum has been formed in ovary after 24,48hours of HCG injection.

注射HCG24h,48h的卵巢中已有黄体形成,Dstn mRNA在黄体化的颗粒细胞上表达。

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