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BACKGROUND: Levosimendan is a novel drug used for inotropic support in heart failure, but its efficacy in local anesthetic-induced myocardial depression is not known.

背景:左西孟旦是一种作用於心衰的新型强心药,但其对於局麻药导致的心肌抑制作用尚未知。

BACKGROUND: Levosimendan is a novel drug used for inotropic support in heart failure, but its efficacy in local anesthetic-induced myocardial depression is not known.

背景:左西孟旦是一种作用于心衰的新型强心药,但其对于局麻药导致的心肌抑制作用尚未知。

The density and pH of a local anesthetic are important characteristics in its use as an intrathecal drug.

麻药的比重和 pH 在其作为椎管内用药时是重要的特性。

Objective Investigating the effect of commonly used local anesthetics on the excitability of the ischiadic nerve of toad, providing electrophysiology basis for clinical use of local anesthetic.

目的 观察常用局麻药对蟾蜍坐骨神经干兴奋性的影响,为临床用药提供电生理学依据。

Results The excitability of ischiadic nerve was surpressed by all of the three local anesthetics and recovered after being washed with Ringer′s solution.

本实验采用整体浸泡的方式,观察常用局麻药普鲁卡因、利多卡因和布比卡因对A

Levobupivacaine is a new , long-acting amide local anesthetic . The physicochemical properties and anaesthesia potence of LEVO and Bupivacaine appear similar . The central nervous system toxicity and cardiotoxicity of LEVO is less than that of BUPI. LEVO can be used extensively in clinic .

左旋布比卡因(Levobupivacaine,LEVO)是一新型、长效酰胺类局麻药,理化性质和麻醉效能与布比卡因(Bupivacaine,BUPI)相似,但心血管系统和中枢神经系统毒性比BUPI低,具有广泛的应用前景。

Forty parturients scheduled for nonemergent cesarean deliverywere enrolled in two groups.

麻药物采用重比重布比卡因(0.75;10.5mg )和吗啡0.15mg ,另外,实验组病人加用哌替啶(0.2mg/Kg ),对照组加用生理盐水。

RESULTS: Continuous paravertebral block was as effective asthoracic epidural analgesia with local anesthetic but wasassociated with a reduced incidence of hypotension.

结果:持续的椎旁阻滞和硬膜外的局麻药镇痛同样有效,并且能降低低血压的发生率。

These results suggest that TSA may be performed on an outpatient basis using perineural local anesthetic infusion.

这些结果提示使用神经周围局麻药注射能使 TSA 在门诊环境中得以实施。

BACKGROUND: In a two-part clinical study, we investigated theeffect of the administration of fluids "prehydration" on thephysical properties of cerebrospinal fluid and intrathecal spread of local anesthetics.

背景:在这项有两部分组成的临床研究中,我们调查了&预先扩容&对脑脊液的物理性质和局麻药在椎管内分布的影响。

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