麦角

These women, ages 61, 72 and 74 years, receiving long-term pergolide therapy for Parkinson's disease or restless legs syndrome, had valvular abnormalities strikingly similar to those induced by fenfluramine, ergot derivatives, or carcinoid. All three had severe, unexplained tricuspid regurgitation; two had predominantly right-sided congestive heart failure; and two had moderate aortic and mitral valve regurgitation. Histology revealed surface fibroproliferative lesions with preserved underlying valve architecture. Carcinoid was excluded, and none of the patients had taken anorectic drugs or ergots other than pergolide.

这3位妇女年龄分别为61、72及74岁，都长期服用pergolide来治疗帕金森氏症或睡眠脚动症，而且也都有不明原因的严重三尖瓣闭锁不全，就像因fenfluramine、麦角衍生物，或类癌肿瘤所引起的瓣膜异常情形一样；其中2位主要有右心衰竭，2位有中度的主动脉及二尖瓣的闭锁不全，组织学检查显现表面有纤维增生性的损伤，但瓣膜的结构仍然还在；类癌是被排除在外的，而且这3位妇女除了pergolide之外，都不曾服用过厌食剂或麦角类药物。

In order to fully utilise the alkaloids in the mother liquor, obtained during the production of ergometrine, and to gain information on the mechanism of biosynthesis, it was necessary to isolate and identify these ergot alkaloids.

为了利用麦角新碱生产过程中母液里的其他麦角生物碱，并为进一步研究生物合成机制提供资料，必须先对母液中所含麦角生物碱进行分离和鉴定。

The effects of different fed-batch methods on the biomass and ergosterol content in Saccharomyces cerevisiae were studied.

研究了不同流加操作条件对实验用酵母菌的生物量和麦角固醇含量的影响，以提高麦角固醇的发酵水平。

The results indicated that ergosterol content was correlated with ethanol tolerance and osmotolerance of saccharomyces cerevisiae strains.

结果表明，麦角甾醇与酵母的耐酒精及耐高渗能力有一定的相关性，耐性好的酵母其麦角甾醇含量较高。

The results showed that the addition of 20 or 30 mg·L^-1 ergosterol promoted the growth of Saccharomyces cerevisiae by 6 % and 15 %, respectively.

结果显示，添加20和30mg L^-1的麦角甾醇能较快的促进细胞的生长，是对照组生长速率的1.06和1.15倍；当麦角甾醇浓度为20、30和40mg L^-1时，与未添加麦角甾醇组相比，乙醇产量提高了10.1％～23.5％：然而，在整个实验过程中观察到麦角甾醇在对乙醇耐受性方面的作用不显著。

Poisoning ca use d by consuming ergot - infected grain or grain products,or from excessive use of drugs containing ergot.

麦角中毒由于进食了被麦角菌感染的谷物或谷物制品，或服用过量的含麦角菌药物而产生的中毒

Results showed that optimal conditions for high content of ergothioneine were moisture content at 40%, temperature at 30℃and polished adlay as medium, cubation 17 days (574.0 mg/kg dw), biomass was 139.0 mg/g dw.

经探讨后，以含水量40%之薏仁於30 ℃下培养17天后之麦角硫因量最高，可达574.0 mg/kg dw，再添加酵母萃取物为氮源可提高麦角硫因到824.8 mg/kg dw，生物质为139.0 mg/g dw；以含水量45%之荞麦於30 ℃下培养17天后之麦角硫因含量最高，可达580.6 mg/kg dw，生物质为163.4 mg/g dw，添加酵母萃取物为氮源，麦角硫因含量可达651.6 mg/kg dw。

Ergothioneine is a kind of precious amino acid, and it is also a natural antioxidant. It plays an important role to prevent the oxidative damage in organism. Ergothioneine cannot be biosynthesized in humans, only can be absorbed from the diet. In recently the research discovered the high content of ergothioneine in the mushroom. Content of ergothioneine of Pleurotus eryngii is the highest from 28 kinds of mushrooms, therefore the research untilized P. eryngii to make the products of P. eryngii-fermented adlay and P. eryngii-fermented buckwheat which content high ergothioneine. Also, we analyzed their proximate composition, nutritional components, taste and physiologically active components, antioxidant properties and evaluation of anti-imflammatory effect.

中文摘要麦角硫因为一种稀有的胺基酸，也是天然的抗氧化剂，其在生物体内对氧化压力伤害之预防扮演著重要角色，麦角硫因不能在动物体内合成，仅能由食物中摄取，近年来发现在菇类中含有高含量的麦角硫因，从28种食药用菇类中筛选出麦角硫因含量较高的菌种，以杏鲍菇子实体最高(1521.6 mg/g dw)，因此本论文以杏鲍菇为媒介，利用固态发酵方式，制备出高麦角硫因之杏鲍菇薏仁和杏鲍菇荞麦，并针对薏仁、杏鲍菇薏仁、荞麦、杏鲍菇荞麦和杏鲍菇菌丝体，进行一般成分、营养、物性、呈味、生理活性物质、抗氧化性质之分析及抗发炎反应之评估。

Results Eleven compounds were obtained and identified as sarcodonin A, scabronine B, 3β-hydroxy-5α, 8a-epidioxyergosta-6, 22-dien,(22E, 24R)-ergosta-7, 22-diene-3β, 5α, 6β-triol,(22E, 24R)-ergosta-7, 22-diene-3β-ol, benzoic acid, 4-hydroxylben-zaldehyde, 4-monopropanoylbenzenediol, ethy1-β-D-glucopyranoside, thioacetic anhydride,(2S, 2'R, 3S, 4R)-2-(2-hydroxyoctadecanoylamino) docosane-1, 3, 4-triol.

结果共分离鉴定了11个化合物，分别是：sarcodonin A、scabronine B、3β羟－5α，5α-过氧麦角甾－6，22-二烯－3β-醇、(22E，24R)-麦角甾－7，22-二烯－3β，5α，6β三醇、(22E，24R)-麦角甾－7，22-二烯－3β-醇、苯甲酸、对羟基苯甲醛、对羟基苯甲酸乙酯、乙基－β-D-吡喃葡萄糖苷、硫代乙酸酐、（25，2'R，3S，4R）-2-（2-羟基－十八碳酰胺）二十二碳烷－l，3，4-三醇。

MethodsErgosterol was separated from Bulgaria inquinants and oxygenized ;its analogue 7-dehydrodesmosterol was also oxygenized. The antituberculous activity of oxygenized products were detected using MTT method.

方法从胶陀螺中分离得到麦角甾醇，对其氧化得到麦角甾醇过氧化物；并对麦角甾醇类似物7-脱氢胆甾醇进行氧化得7-脱氢胆甾醇过氧化物；用MTT法检测其氧化产物的抗结核活性。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。