鸟苷

It has been developed as an anti-hepatitis B virus agent for treatment of chronic hepatitis B virus infection by Bristol-Myers Squibb Company.

恩替卡韦是一种有效的、选择性抑制乙型肝炎病毒复制的脱氧鸟嘌呤核苷类似物，由Bristol MyersSquibb公司研究开发，用于治疗乙型肝炎。

Based on the previous literatures, the following major innovation works were carried out in this dissertation:(1) The derivatization reaction conditions of ephedrine and pseudoephedrine with sensitive derivation reagent in aqueous system were studied and two new methods were developed for the assay of them by microemulsion electrokinetic chromatography and micellar electrokinetic chromatography with LIF detection. The sensitivity and analysis times were greatly improved compared with the previous reports;(2) A new method of CZE with indirect LIF detection was developed for the simultaneous determination of six coumarin compounds (esculin, esculetin, isofraxidin, genistein, naringin and sophoricoside) with fluorescein as the probe. The proposed method enlarges the application range of LIF detector, and provides new approach for the analysis of certain compounds difficult to derivatize;(3) Based on the above research, an MEKC with indirect LIF detection method for the simultaneous determination of adenine and guanine in DNA extracts from fungus, maize and soybean was established;(4) A new method for the investigation of the complexes formed between human serum albumin and ampicillin sodium under the simulated physiology conditions using laser light scattering technique was developed.

该论文在综述前人工作的基础上，开展了如下未见文献报道的创新性的研究工作：(1)使用灵敏的衍生试剂对麻黄碱和伪麻黄碱在水体系中的衍生反应条件进行了系统研究，建立了微乳电动色谱-激光诱导荧光检测法和胶束电动色谱—激光诱导荧光检测法测定麻黄碱和伪麻黄碱的灵敏分析新方法，与以前的报道相比，灵敏度和分析时间均有很大改善；(2)使用荧光素钠作为背景荧光试剂，建立了同时分析测定六种黄酮类化合物(秦皮甲素、秦皮乙素、异秦皮定、染料木素、柚皮苷和槐角苷)的毛细管区带电泳—间接激光诱导荧光检测新方法，扩大了激光诱导荧光检测的应用范围，对难衍生化合物的分离分析提供了一种新思路和新途径；(3)以荧光素钠作为背景荧光试剂，建立了一种用于同时测定食品提取DNA中的腺嘌呤和鸟嘌呤含量的胶束电动色谱—间接激光诱导荧光检测新方法；(4)用动态和静态激光散射法研究了模拟生理条件下人血清白蛋白与氨比西林钠盐相互作用所形成的复合物，为药物分子与蛋白质的相互作用、药代动力学等的研究提供了一种新思路。

Post-transcriptional modification in which a derivative of guanosine is attached to the 5' end of the pre-mRNA.

将鸟嘌呤核苷的衍生物加到前体mRNA 5'端上去的转录后修饰作用。

MPA was shown to hae a distinct anti-HC mechanism of action, independent of cell proliferation and guanosine depletion.

麦考酚酸表现出一种特殊的抗丙肝病毒复制的作用机制，它不依赖细胞增殖及鸟嘌呤核苷消耗。

In this paper, three gene S-adenosylmethionine decarboxylase, ornithine aminotransferase and betaine aldehyde dehydrogenase plus one house-keeping gene had been cloned and their expression levels under different stresses were evaluated by real-time PCR technique.

已克隆S-腺苷蛋氨酸脱羧酶、鸟氨酸氨基转移酶、甜菜碱脱氢酶3个基因和内参基因的基础上，应用定量PCR技术，对这3个基因在不同胁迫时间下的表达水平进行分析。

Methods 108 patients with icteric chronic viral hepatitis were randomly divided into three groups,who received 4 weeks treatment with intravenous L-ornithine-L-aspartate,S-adenosyl-L-methionine, potassium magnesium aspartate, respectively.

方法将108例黄疸型慢性病毒性肝炎患者随机分为3组，分别接受4周的门冬氨酸-鸟氨酸、腺苷蛋氨酸和门冬氨酸钾镁等治疗，并检测患者治疗前后的血清总胆红素。

Part II:The electrocatalytic oxidation of guanine, adenine, guanosine-5'-monophosphate and ssDNA was performed in the presence of iron bis(2,2':6',2"-terpyridine) and Fe tris(1,10-phenanthroline) complexes as a homogeneous catalysts with Fe redox couple. The electrocatalytic and electroanalytic properties of guanine with an iron bis(2,2':6',2"-terpyridine) complex was measured by the amperometry method using the rotating disk electrodes. Electropolymerization of iron tris(5-amino-1,10-phenanthroline) complex produced thin polymer films on a gold, platinum, nickel, and glassy carbon electrode.

第二部分利用iron bis(2，2'：6'，2&-terpyridine)和Fetris(1，10-phenanthroline)之金属错合物当作均相的催化剂对於鸟嘌呤、腺嘌呤、5'-鸟嘌呤核苷单磷酸盐(guanosine-5'-monophosphate)和单股DNA进行电催化氧化的研究。iron bis(2，2'：6'，2&-terpyridine)之金属错合物对於鸟嘌呤的电催化和电分析性质可利用计时安培法并使用旋转环-碟电极进行测量。rontris(5-amino-1，10-phenanthroline)之金属错合物可经由电聚合过程所形成的聚合薄膜固定在黄金、白金、镍和玻璃碳电极上。

The cordyceps grass vegetable, the cordyceps grass is sour, the cordyceps grass many sugar, SOD—enzyme, guanin, urine, the gland... etc., a materials of the pit are all with the natural cordyceps grass homology, the poison reason evaluation:Have no poisonous side effect to the human body, is a stub in the world new species of biggest cordyceps grass in very unique body.

虫草素、虫草酸、虫草多糖、SoD、腺嘌岭、鸟嘌呤、尿嘧啶、腺苷等，核苷类物质都与天然虫草相同，毒理评价：对人体无任何毒副作用，是一株世界上绝无仅有形体最大的虫草新品种。

Any of various compounds consisting of a sugar, usually ribose or deoxyribose, and a purine or pyrimidine base, especially a compound obtained by hydrolysis of a nucleic acid, such as ''.

核苷由糖，通常是核糖或脱氧核糖和嘌呤或嘧啶基组成的化合物，尤指从核酸水解中获得的化合物，如腺嘌呤核苷或鸟嘌呤

Any of various compounds consisting of a sugar, usually ribose or deoxyribose, and a purine or pyrimidine base, especially a compound obtained by hydrolysis of a nucleic acid, such as adenosine or guanine.

核苷由糖，通常是核糖或脱氧核糖和嘌呤或嘧啶基组成的化合物，尤指从核酸水解中获得的化合物，如腺嘌呤核苷或鸟嘌呤

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。