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The main contents in this thesis go as follows.The polymorphic transition process of 5'-GMPNa2 from amorphism to crystal was investigated by in-situ monitoring technique and ex-situ monitoring technique. The transition mechanism was deduced to be solution mediated transition.

具体研究内容如下:利用聚焦光束反射测量仪、颗粒图像测量仪和X射线粉末衍射仪等测试手段对5'-鸟苷酸二钠由无定形体转化为晶体的过程进行了研究,推断出其过程机理为溶液过渡转化。

MoRGF1 was highly identical in amino acids with its homologs from other filamentous ascomycete fungi. The gene eletion mutants displayed slower growth and obviously reduced conidiation, although with no change in pathogenicity when compared with their wild type strain.

结果表明Mgg_11178.6编码一个假定的Rho族小G蛋白鸟苷酸交换因子(MoRGF1),与多种丝状子囊菌RhoGEF亲缘关系密切;基因敲除突变体表现为生长速度减慢,产孢量明显减少,但是致病力没有变化。

Komata T,Kondo Y,Kanzawa T,Hirohata S,Koga S,Sumiyoshi H,Srinivasula SM,Barna BP,Germano IM,Takakura M,Inoue M,Alnemri ES,Shay JW,Kyo S,Kondo S.

在人骨肉瘤143B移植瘤模型,两种载体一次注射继以丙氧鸟苷治疗可引起相同程度的肿瘤消退。

By the use of X-ray single crystal diffraction technique, the crystal structure of 5'-GMPNa2 was determined.

利用X-射线单晶衍射仪测定了I型5'-鸟苷酸二钠晶体结构。

Affer 4 to 8 weeks, the serum n itric oxide, plasma endotheliolysin, cGMP and lipid peroxide were meas ured and morphologic change of renal tissue examined.

为探讨穿心莲API0134防治家兔系膜增殖性肾炎作用机理,采用高胆固醇饲料另加牛血清白蛋白一次性注射方法建立家兔M sPGN模型,观察4~8周,检测血清一氧化氮,血浆内皮素,环鸟苷酸(cGMP 脂质过氧化物以及肾组织形态学改变。

Manufacture of a new submachine gun, designated as MP-38, commenced in summer of 1938, at Erma, and later on also at CG Haenel.

制造一个新的冲锋枪,为手机指定- 38,1938年开始在夏天厄马,后来又在鸟苷海内尔。

Objective To establish a method for determination of guanosine in fermented produots.

目的 建立测定发酵产品中鸟苷含量的方法。

Objective To investigate the effect of electroacupuncture on nitric oxide and cyclic guanosine monophosphate levels in penile tissues of rats with depression.

目的 研究电针对抑郁症模型大鼠阴茎组织一氧化氮和环磷酸鸟苷的影响。

The main research contents and results are as follows:(1) The method of chromatography paper was defined to determinate guanosine content quantitatively in the fermentation broth.

主要研究内容和结果如下:(1)建立了发酵液中鸟苷定量测定的"纸层析-色斑洗脱比色法",并对该方法的应用条件进行了研究。

Guanosine overproducing mutant was derived from Bacillus subtilis T1001 by using ultraviolet and diethyl sulfate. The mutant was selected directionally and step wisely on the agar plates containing methionine sulfoxide and 8 azaguanine(8 AG).

以枯草芽孢杆菌T1 0 0 1为出发菌株,经紫外线、硫酸二乙酯逐级诱变处理,选育出腺嘌呤缺陷型菌株,然后经蛋氨酸亚砜、8 氮鸟嘌呤( 8 AG)结构类似物平板定向筛选,获得鸟苷高产菌株TA2 0 8。

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