鸟苷

Guanosine monophosphate reductase catalyzes the NADPH-dependent reductive deamination of Guanosine monophosphate to inosine monophosphate .

鸟苷酸还原酶(guanosine monophosphate reductase，GMPR)(EC 1.6.6.8)主要催化鸟嘌呤核苷酸向次黄嘌呤核苷酸的转化：GMP+NADPH+2〓→IMP+〓+NADP〓。

ResultsThe linear range of guanosine was within 0.048～0.480 μg,r=0.999 9,the RSD of recovery(n=9) was 2.94%.

结果鸟苷在0.048～0.480 μg范围内线性关系良好，r=0.999 9，腺苷在0.045～0.449 μg范围内线性关系良好，r=

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

of identification of 5'-guanylic acid(5'-GMP) and 5'-inosinic acid(5'-IMP) in concentrated gourmet powder is described.

本文描述了一种快速测定增鲜味精中的5'－鸟苷酸（5'－GMP）和5'－肌苷酸（5'－IWP）的方法。

RP-HPLC ; Concentrated Gourmet Powder ; 5'-guanylic acid（5'-GMP）; 5'-inosinic acid

HPLC－反相色谱；增鲜味精； 5'－鸟苷酸（5'－GMP）； 5'－肌苷酸

Inosine -5'- monophosphate (5'-IMP) and guanosine-5'-monophosphate (5'-GMP) in samples were separated successfully using an Inertsil ODS-3 column (250 mm×4.6 mm, 5 μm) when 0.02 mol/L monopotassium phosphate (pH 4.5) was employed as the mobile phase with a flow rate of 1.0 ml/min at 250 nm and 25℃.

采用Inertsil ODS-3色谱柱(250 mm×4.6 mm， 5μm)；以0.02 moL/L磷酸二氢钾溶液(pH 4.5)为流动相，流速1.0 mL/min，柱温25℃，检测波长250 nm，同时分离了样品中5'-鸟苷酸二钠和5'-肌苷酸二钠。

The results show that before treatment with Chinese herb, the content of plasmatic cAMP is decreased, while cGMP is increased, cAMP/cGMP is decreased (P＜0.01) in group T.

对中药组60例患者，采用放免分析法测定中药治疗前后血浆环—磷腺苷cAMP、环—磷鸟苷cGMP含量，以40例健康女性的检测值做为对照组进行比较。

Results The pD2 value (the affinity to M-receptors of agonist) of Erycibele alkaloid's miosis is 3.60±0.15 and its IOP lowering action is 3.49±0.07. In the isolated iris contracting experiment, its pD2 value is 6.38±0.12. M3 receptor antagonist is the strongest antagonist in inhibiting the miosis, IOP lowering action and isolated iris pupillary contracting action of Erycibele alkaloid. 0.01% Erycibele alkaloid can cause the decrease of cAMP and the increase of cGMP in the aqueous humor.

结果 测定丁公藤碱缩瞳作用的pD2值为3.60±0.15，降眼压作用的pD2值为3.49±0.07，离体虹膜收缩作用的pD2值为6.38±0.12.M1～M3受体拮抗剂均可拮抗丁公藤碱的缩瞳作用、降眼压作用及离体虹膜收缩作用，其中以M3受体拮抗剂的拮抗作用最强。0.01％丁公藤碱可使房水环磷酸腺苷(cyclic adenosine monophosphate，cAMP)含量降低，环磷酸鸟苷(cyclic guanosine 3，5-monophosphate；cGMP)含量升高。

AIM: To investigate killing effect of herpes simplex virus thymidine kinase/ganciclovior system on osteosarcoma cell and its mechanisms.

目的：观察单纯疱疹病毒胸苷激酶/丙氧鸟苷基因治疗系统对骨肉瘤细胞株OS732的杀伤作用并研究其作用机制。

In vivo gene therapy of ovarian cancer by adenovirus－mediated thymidine kinase gene transduction and ganciclovir administration.

羟甲基无环鸟苷对携有单纯疱疹病毒胸腺嘧啶核苷激酶基因人卵巢癌裸鼠皮下移植瘤生长的抑制作用。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。