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鸟嘌呤

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In DNA, four different bases are found. Two of these, adenine and guanine , are double-ring structures called purines.

在DNA中,有四种不同的碱基,其中的两个为腺嘌呤和鸟嘌呤,即称为嘌呤的双环结构。

RNA editase transforms or modifies the nucleotide of pre-RNA by deaminization, and hydrolytic deaminize C6 amino group of the adenosine at the specific RNA site, changing adenosine to inosine or changing cytosine to uracil,but inosine was recognized as guanine in mRNA.

RNA编辑酶以脱氨方式使得RNA特异位点的腺嘌呤脱氨转变为次黄嘌呤,或者是特异位点的胞嘧啶变为尿嘧啶,而次黄嘌呤在碱基配对时被识别为鸟嘌呤

Members of the purine group include adenine and guanine, which are constituents of the nucleic acids, and certain plant alkaloids, e.g.

嘌呤基的成员包括腺嘌呤和鸟嘌呤,它们是核酸以及某些植物生物碱的成分,如咖啡因和可可碱。

Adenine and guanine are purines and cytosine and thymine are pyrimidines.

腺嘌呤和鸟嘌呤是嘌呤和胞嘧啶和胸腺嘧啶是嘧啶。

Object: The purpose of this study was to supply people with scientific dietary instructions by investigating the change of the content of adenine, guanine, xanthine and hypoxanthine in two Huahuang fish and carp during boil processing. Method The HPLC method was accepted.

目的:通过检测经过水煮的黄花鱼和鲤鱼中腺嘌呤、鸟嘌呤、黄嘌呤、次黄嘌呤的含量,探索在高温水煮过程中嘌呤含量的变化,希望以此为人们的健康饮食提供科学的指导基础。

The reactivity of guanine, adenine and hypoxanthine on electrodes made with different materials is discussed. The rough pyrolytic graphite electrode was selected for the electrochem. study.

本文讨论了鸟嘌呤、腺嘌呤和次黄嘌呤等嘌呤类生物小分子在几种电极上的反应活性,并选用粗热解石墨电极研究了它们的电化学性质。

The content of purines in soup increased sharply during 10 min, increased slowly during 10 min to 60 min. The content of adenine in carp weighed 200 g increased during boiling process, that of guanine was stable, that of total purines and hypoxanthine decreased. The content of total purines and four purines in Huahuang fish decreased during boil processing.

鱼汤中嘌呤含量在10min内迅速升高,10~60min缓慢升高。200g鲤鱼中腺嘌呤含量在水煮加热过程中升高,鸟嘌呤含量无明显变化,总嘌呤和次黄嘌呤组分含量下降,200g黄花鱼的总嘌呤及4种嘌呤组分含量在水煮加热过程中下降。

Part II:The electrocatalytic oxidation of guanine, adenine, guanosine-5'-monophosphate and ssDNA was performed in the presence of iron bis(2,2':6',2"-terpyridine) and Fe tris(1,10-phenanthroline) complexes as a homogeneous catalysts with Fe redox couple. The electrocatalytic and electroanalytic properties of guanine with an iron bis(2,2':6',2"-terpyridine) complex was measured by the amperometry method using the rotating disk electrodes. Electropolymerization of iron tris(5-amino-1,10-phenanthroline) complex produced thin polymer films on a gold, platinum, nickel, and glassy carbon electrode.

第二部分利用iron bis(2,2':6',2&-terpyridine)和Fetris(1,10-phenanthroline)之金属错合物当作均相的催化剂对於鸟嘌呤、腺嘌呤、5'-鸟嘌呤核苷单磷酸盐(guanosine-5'-monophosphate)和单股DNA进行电催化氧化的研究。iron bis(2,2':6',2&-terpyridine)之金属错合物对於鸟嘌呤的电催化和电分析性质可利用计时安培法并使用旋转环-碟电极进行测量。rontris(5-amino-1,10-phenanthroline)之金属错合物可经由电聚合过程所形成的聚合薄膜固定在黄金、白金、镍和玻璃碳电极上。

Comparative studies of electroactive components and voltammetric behaviors different between the MCF-7 cell without estrogen and the MCF-7 cell with estrogen showed that the concentration of the guanine and xanthine bases in the cytoplasm decreased, which resulted in the decrease of secretion ability of the MCF-7 cell without estrogen decreased, and these result in the decreasing of the voltammetric response of the cells, impling that the cell vaibility decreases.

结果发现,去激素MCF-7细胞质中的黄嘌呤和鸟嘌呤浓度降低,使细胞分泌黄嘌呤和鸟嘌呤能力降低,导致细胞和细胞质的伏安信号减弱,说明去激素MCF-7细胞的活性下降;研究了标准雌激素雌二醇、环境雌激素壬基酚和双酚A对去激素培养的MCF-7细胞增殖的影响,发现其均存在剂量-效应关系和时间-效应关系,并且雌激素效应由大到小的顺序为:雌二醇>壬基酚>双酚A;同时使用3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide法验证了电化学法评价雌激素效应的可靠性。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本论文主是采用以鸟嘌呤为原料,经过一系列的酰基化,脱羧,还原等反应作用下最终得到了产物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤;其中的中间体衍生物主要是阐述从以2-氨基-6-氯鸟嘌呤为原料通过在不同的条件下进行溴代与碘代分别合成了另外两种中间体2-氨基-6-溴鸟嘌呤及2-氨基-6-碘鸟嘌呤;还有一部分主要是阐述从以苯乙酮,盐酸氨基脲,苯肼,乙酰乙酸乙酯为原料通过一系列的反应先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛这两个吡唑醛,然后再与2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反应得到了两个新型的吡唑嘌呤席夫碱

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