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鳞状上皮细胞

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Cancer of the larynx and hypopharynx is one of the most common head and neck malignancy. Squamous cell carcinoma remains the most common pathologic type, accounting for more than 90% cases. Although therapeutic modality has improved gradually, there is no sign that the 5-year survival rate has improved during the past 20 years. The metastasis of tumor cells represents the primary source of clinical morbidity and mortality in the large majority of laryngeal and hypopharyngeal tumors.

中文摘要喉癌及下咽癌是常见的头颈部癌症之一,它的组织病理学诊断百分之九十以上为鳞状上皮细胞癌,虽然医学逐渐进步,但此疾病患者的存活率在最近20年内并没有增加的现象,对咽喉癌病患的治疗而言,是否出现淋巴结及远隔转移对预后具有决定性的影响。

These results revealed that overexpression of c-Myc upregulated telomerase, which in turn resulted in immortalization of laryngeal squamous cells, and this mechanism existed not only in the initiation of laryngeal carcinogenesis but also in the whole process of cancer development.

这些研究表明,喉癌的发生可能是由于c-Myc的过度表达使端粒酶表达上调,从而使喉鳞状上皮细胞达到永生化,这一机制不仅存在于喉癌发生的早期,而且贯穿于喉癌的发展过程。

Note:There is moderate dysplastic change of the squamous epithelium.

注:这是鳞状上皮细胞中度异常变异,建议做锥状切除。

Objective To determine the clinical significance of the expression of apoptosis in esophageal squamous cell carcinoma.

目的 探讨食管鳞状上皮细胞癌中细胞凋亡的表达及其临床意义。

In the second part of our research, YC-1, an indazole derivative, displayed impressive selective toxicity against the human lung squamous carcinoma cell line NCI-H226 and human kidney tumor cell lines RXF-631L by a panel of 39 human cancer cell lines (JFCR39) screening. Therefore, the molecular mechanism by which YC-1 affects NCI-H226 cell growth was studied.

在本论文的第二部份中,吲唑类化合物YC-1经利用日本JFCR39癌细胞株之抗癌活性筛选后发现,YC-1对於人类肺鳞状上皮细胞癌细胞NCI-H226以及人类肾癌细胞RXF-631L具有高度的抑制选择性,於是我们选择NCI-H226细胞株做为YC-1对抗肺癌之抗癌机制探讨模式细胞。

Results The FHIT protein is located in the cytoplasm or nuclear of normal vulvar squamous epithelium....

结果:FHIT蛋白定位于正常外阴鳞状上皮细胞的细胞浆或细胞核内。60例外阴癌中,13例(21.7%)FHIT蛋白表达呈阳性,58例(96.7%)EGF蛋白表达阳性。

Results Normal imbricate epitheliums and LSIL and HSIL and cancer cells were recognized and classified, the recognition rate of training set was 98.29%, the recognition rate of test set was 96.57%.

结果 细胞按正常、低度和高度鳞状上皮细胞、癌细胞进行分类识别,训练集与测试集识别率分别为98.29%、96.57%。

Objective: To investigate amplification of the human telomerase RNA component gene in the cervical exfoliated cells and to explore its value in diagnosis and treatment of cervical intraepithelial neoplasia and malignancy.

目的:研究宫颈脱落细胞中人端粒酶RNA组分基因的表达,探讨其在宫颈上皮内瘤变及鳞状上皮细胞癌诊断中的价值。

August 21, 2008 — Specific skin-odor profiles can be used to identify basal-cell carcinoma, researchers reported at the American Chemical Society 236th National Meeting and Exposition. These findings may eventually translate into novel and effective methods of diagnosing not only basal-cell carcinoma, but also squamous-cell cancer and melanoma.

August 21, 2008 —研究者在美国化学会第236届年会与展览中指出,特定的皮肤味道档案可以作为辨识基底细胞癌的工具,这些发现最终可以变为基底细胞癌和鳞状上皮细胞癌、黑色素瘤之新的有效诊断方式。

The researchers calculate that if moderate- or heavy-drinking ALDH2-deficient Japanese men reduced their consumption to under 16 drinks a week 53 percent of esophageal squamous cell cancers in that group could be prevented.

研究人员计算了一下适度或者大量饮酒且缺乏ALDH2的日本男人每周少喝16瓶酒的情况,发现这一组人中患上食道鳞状上皮细胞癌的风险减少了53%。

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