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Rotenone was used on NGF-differentiated PC12 cells to induce apoptosis.

以NGF诱导后的PC12细胞作为细胞模型,采用鱼藤酮诱导细胞凋亡。

Our results show that low doses of chronically and intragastrically administered rotenone induce PD pathology in all the above-mentioned nervous system structures in wild-type mice.

我们的结果表明,低剂量的长期和灌餵鱼藤酮诱导帕金森病理学所有上述神经系统结构,野生型小鼠。

Perennial subshrub of eastern North America having downy leaves yellowish and rose flowers and; source of rotenone.

北美东部的一种多年生亚灌木,叶具有绒毛,花紫黄色;鱼藤酮的来源。

Toxicity of four compounds identified as 6a, 12a-dehydro-α-toxicarol, 6a, 12a-dehydro-deguelin,-tephrosin and-6-hydroxy-6a, 12a-dehydro-toxicarol obtained from the leaves and stem of Amorpha Fruticosa and their mixture in a natural ratio 1:2.54:4.18:2.54 were tested against Trematodes grandis.

通过对紫穗槐叶和茎成分分离,得到6a,12a-脱氢-α-灰叶酚、6a,12a-脱氢鱼藤素、灰叶素、6-羟基-6a,12a-脱氢灰叶酚4个化合物。

Both can be adapted to account for the effect of "uncouplers" of oxidative phosphorylation such as rotenone,amytal,antimycin A,etc,which have the effect of stopping ATP production.

双方能够适应为&uncouplers氧化磷酸化&的效果帐户,如鱼藤酮,阿米妥,抗霉素阿等,它们具有阻止ATP生产的影响。

MTT assay and morphological observation were used to evaluate the toxicity of rotenone on astroglia,cell proliferation and the expression of CX43 mRNA were detected by growth curve analysis and RTPCR.

观察染毒星型胶质细胞形态,检测细胞活力,通过生长曲线分析鱼藤酮对星型胶质细胞增殖的影响以及RTPCR检测缝隙连接蛋白(connexin43,CX43)mRNA表达。

MTT assay arid morphological observation were used to evaluate the toxicity of rotenone on astroglia, cell proliferation and the expression of CX43 mRNA were detected by growth curve analysis and RT-PCR.

观察染毒星型胶质细胞形态,检测细胞活力,通过生长曲线分析鱼藤酮对星型胶质细胞增殖的影响以及RT-PCR检测缝隙连接蛋白(connexin43, CX43)mRNA表达。

The study was purposed to investigate the effect of deguelin on expression of nucleoporin 98(nup98) in leukemia K562 cells.

本研究观察鱼藤素对白血病细胞株K562细胞核孔蛋白nup98表达的影响。

Deguelin induced DNA fragmentation and apoptotic cell death in a dose-dependent manner, which was accompanied by typical morphological changes associated with apoptosis.

3鱼藤素能同时在蛋白和基因水平,以剂量依赖性方式抑制核孔蛋白Nup88、Nup214以及核磷蛋白NPM的表达。

Objective To investigate antitumor activity and molecular mechanism of deguelin to the human U937 leukaemia cells and to explore the mechanisms regulating cell cycle and nucleoporin 98 (Nup98) and nucleoporin 88 (Nup88) in vitro.

目的研究鱼藤素对人类白血病细胞株U937细胞体外抗肿瘤作用,研究其引起细胞周期与核孔蛋白Nup98和Nup88的改变,探讨其抗癌作用的分子机制。

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