高血压

Genetic factors,obesity, high salt consumption, and alcohol may be involved in the pathogenesis of essential hypertension. Jannetta et al. suggested that essential hypertension might be associated with vascular compression of the left rostral ventrolateral medulla and the root entry zone of cranial nerves Ⅸ and Ⅹ by ectatic loops of posterior fossa arteries,described as neurogenic hypertension.

原发性高血压的发生可能与遗传、肥胖、高盐饮食、饮酒等综合因素有关。1979年Jannetta等提出由于后颅窝异常血管袢压迫延髓左侧腹外侧、舌咽神经与迷走神经根入脑干区(Root entry zone， REZ)而引起高血压即神经源性高血压的假说以来，不少学者从临床及实验研究证实了Jannetta的假说。

With the development of lesion inautonomic nervous system, i.e. the elevation of baroreflex set point, blood pressureincreases to stage 1 hypertension and worsens. Furthermore, the role of the effectors,including PVR, ventricular end-systolic elastance, venous unstressed volumes and heartrate, in the regulation of hypertension was analyzed. The results exhibit that the ANSregulation on hypertension works mainly by the reduction of PVR and the increase ofvenous unstressed volume.

随着自主神经系统损坏程度的不断加重，即工作调定点进一步升高，血压水平上升到了1级高血压并趋于严重；研究了神经调节的各效应器(外周血管阻力、心肌最大弹性度、心率和静脉非压力容积)对高血压的作用，表明神经调节机制对高血压的调节主要是通过降低外周血管阻力和增加静脉非压力容积实现的。

The molecular mechanism in hypertensive kidney lesion was demonstrated by monitoring the levels of serum TGF-β, nitric oxide and plasma AngH in essential hypertensive patients and investigating the effect of information convection in endothelial cell on fibrillar collagen metabolism and its relationship with hypertensive kidney lesion.

该课题通过测定原发性高血压病人及伴肾脏损害病人的TGF-β_1、NO和Ang Ⅱ的水平，探讨内皮细胞产生的信息传递对纤维胶原代谢的影响及与高血压性肾损害的关系，以揭示高血压性肾损害发生发展的细胞分子机制。

Patients measure up hyperpietic diagnosetic standard according to syndromes differ types were divided into the following four types as the GanhuoKangsheng Type,the YinXuyangKang Type,the YinYangLiangXu Type,and the TanShiYongSheng Type,observe the blood pressure、the stage of hypertensive diseases、the course of diseases and the changes in fodus,stat and analyse these datum, ascertain the relationship between hypertensive retinopathy as well as the blood pressure、the course of hypertension and the TCM syndrome types,then discuss the influence that age and lipid act on retinopathy.

对符合高血压诊断标准的132例原发性高血压病患者进行中医辨证分型为肝火亢盛型、阴虚阳亢型、阴阳两虚型、痰湿壅盛型，观察血压水平、分级、病程、视网膜病变，对调查资料进行统计分析，探讨高血压性眼底血管病变、血压水平、病程与中医证型之间的相关性，并探讨年龄、血脂因素对眼底血管改变的影响。

The fundus showed hypertensive retinopathy (arteriolar constriction, hemorrhage, cotton wool spots, and focal intraretinal periarteriolar transudates), hypertensive choroidopathy (exudative retinal detachment, choroidal infarction, and RPE degeneration), and hypertensive optic neuropathy.

眼底可以看到高血压视网膜病变（动脉挛缩，网膜出血，棉花状斑，以及局部网膜内动脉旁漏出物FIPTs），高血压脉络膜病变（渗出性视网膜剥离，脉络膜梗塞，以及色素网膜变性），及高血压视神经病变。

The mesentery arteries of hypertension patient and patient with normal blood tension were used in my study, the ion channel change which might involved in the generation and development of hypertension was investigated further through the comparative studies on the expression of compositive subunit gene of large conduction calcium—activated potassium channels in vascular smooth muscule of mesentery artery, so more experimental datas were provided to elucidate the pathological mechanisms of hypertension.

本课题选取原发性高血压患者和正常血压患者的肠系膜动脉，对肠系膜动脉血管平滑肌大电导钙激活钾通道组成亚单位基因表达进行对比研究，进一步探讨原发性高血压发生发展过程中可能的离子通道改变，为高血压发病机制的阐明提供更多的实验依据。

Abnormalities of fi-brinolytic activity and TGF-J31 levels play an statistically significant role in benign arteriolar nephrosclerosis due to primary hypertension.

原发性高血压早期即有TGF-β1及PAI-1的高水平表达，并在高血压性肾损害病程中持续性高水平表达，作用于高血压性肾损害病程的始终。

Objective To investigate the roles of AngU ,fibrinolytic activity and transforming growth factor -fil (TGF-f31) in benign arteriolar nephrosclerosis due to primary hypertension.Methods 192 patients of primary hypertension were divided into 3 groups according to the degree of hypertension.

目的 通过测定192例原发性高血压患者及52例正常人尿转化生长因子-β1(TGF-β1)、血浆凝血酶原激活物抑制物-1(PAI-1)、血管紧张素Ⅱ含量，观察其在不同分级、不同肾损害程度的高血压患者的表达水平，以探讨其与高血压性肾损害发生发展的关系。

A group of national research shows that 2000 cases of hypertension, orthostatic hypertension accounted for 4.2 percent of all high blood pressure.

国内一组2000例高血压研究表明，体位性高血压占所有高血压的4.2%。

1MmHg (p=0.027) in seating and supping systolic blood pressure, respectively. No association between the polymorphism and blood pressure was detected in female hypertensive. This result suggest that the T allele confers an increasd risk of developing hypertension.

而男性高血压患者的舒张压及女性高血压患者的血压与C-511T多态位点无相关性，该结果提示，白介素1β基因C等位基因是男性高血压发病的一个危险因素。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。