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Compared with SHRc , after 4 weeks, Pro-EGF mRNA expression level of SHRsv and SHRlv VSMC were significant lower.Conclusions: Valsartan decrease SBP of SHR, inhibit SHR VSMC proliferation, reverse vascular hypertrophy of thoracic aorta and mesenteric artery in SHR, improve the two arteries vasomotion function. Pro-EGF mRNA expression only in SHR VSMC, not in the VSMC of WKY. It indicated pro-EGF gene may play an important role in hypertension advance .

缬沙坦有效降压的同时,抑制SHR大鼠VSMC增殖,逆转其弹性血管和阻力血管的肥厚,明显改善其弹性血管和阻力血管的舒缩功能。pro-EGF mRNA只在SHR大鼠VSMC表达,而在WKY大鼠VSMC没有表达,提示pro-EGF基因可能在高血压的发生发展中起一定的作用,可能是高血压的一个病理机制。

Results Among the 40 cases with the tumor incised, the specimens were 2 to 9cm in size.

随访6个月-19年,43例高血压患者术后血压正常31例、仍有高血压2例。

One, the United States Society of Hypertension classification of hypertension was made the new definition, which reads as follows table

一、美国高血压学会对高血压的分类作了新的界定,其内容如下表

Objective: To investigate the relationship between age or period of hypertension and morphological remodeling of renal arterioles.

目的:探讨高血压大鼠年龄、高血压持续时间与肾内小动脉形态学重建的关系。

Methods The pathological changes of the deep cerebral white matter arterioles in cerebral infarction patients with and without LA were observed.

方法通过病理学观察13例伴LA的高血压脑梗死患者和10例不伴LA的高血压脑梗死患者脑小动脉病理变化。

For the 132 people whose breathing stopped between 5 and 15 times per hour,the risk or high blood pressure doubled from that of the regular breathers. And among the 67 people whose breathing stopped 15 or more times per hour,the risk nearly tripled.

132名每小时停止4到15次的人,患高血压的概率是呼吸正常人的两倍。67名每小时呼吸停止15次甚至15次以上的人,患高血压的概率几乎是正常人的三倍。

Chronic and persistent hypertension will activate circulatory and focal rennin-angiotensin-aldosterole-system, which plays an important role in hypertension development and target organ detriments.

高血压时持续的压力负荷增加可激活一系列神经-体液因子,如循环和局部的肾素-血管紧张素-醛固酮系统在高血压的发生、发展和靶器官损害过程中具有重要的作用。

Results The frequency of early damage of kidney in non-dippers was higher than that in dippers.

结果 非勺型高血压组与勺型高血压组相比,尿微量白蛋白的阳性率显著增高(P=0.001)。

Diuretics is used widely in treatment of hypertension,especially in salt sensitivity hypertension.

利尿剂广泛用于高血压的治疗,对盐敏感性高血压有较强的降压效应。

Methods A total of 125 cases including 40 hypertension patients without LVH, 45 hypertension patients with LVH and 40 control subjects underwent color Doppler ultrasonography. Intima-media thickness, plaque and hemodynamic indices were respectively measured in the common carotid artery and its bifurcation, internal carotid artery and external carotid artery.

对134例受检者进行颈动脉超声研究,其中高血压病非LVH 32例,高血压并LVH 62例,正常对照组40例,分别测量各组颈部动脉总干内中膜厚度、分叉内中膜厚度、斑块以及两侧颈总动脉、颈内动脉、椎动脉的血流动力学指标。

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