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高血压

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Abstract] objective to observe the effects of indapamide and losartan alone and combined treatment on the elder patients with hypertension,hypokalemia,hyperglycemia,uric acid,lipid,ect.methods one hundered and fifty patients with hypertension were randomly divided into three groups,with each of 50 cases.the levels of blood pressure,hypokalemia,blood sugar,uric acid,lipide were examined before and after treatment.results after 8 weeks the systolic and diastolic blood pressure were significantly lower.antihypertensive treatment group is the best,the levels of hypokalemia is lower after treatment in the indapamide group,the levels of uric acid is also lower in the losartan group and antihypertensive group.conclusion losartan and indapamide combined treatment not only coordinate to decrease blood pressure but also reduce uric acid,reduce the effect of hypokalemia caused by indapamide.

目的 观察氯沙坦与吲哒帕胺单独应用或联合用药对原发性高血压患者血压、血钾、血糖、尿酸、血脂的影响。方法将符合诊断标准的150例老年高血压患者电脑随机分为3组,每组50例,进行用药前后自身对照试验,8周后检测各组血压、血钾、血糖、尿酸、血脂值。结果 3组治疗后收缩压和舒张压均较前明显降低,联合治疗组降压幅度最大,氯沙坦组和联合治疗组治疗后尿酸值较治疗前降低,吲哒帕胺组治疗后血钾值较治疗前降低。结论氯沙坦与吲哒帕胺联合应用不仅具有协同降压作用,而且能降低尿酸,减轻吲哒帕胺引起的低钾血症。

With 〓H-TdR incorporation and cell count, we found that AdM could inhibit DNA synthesis and the proliferation of VSMCs from SHR. With semiquantitative RT-PCR analysis, we found that AdM mRNA level was lowerer in kidney and VSMCs from SHR than those from WKY.

应用〓H-TdR掺入和细胞计数发现,AdM可以抑制培养的自发性高血压大鼠VSMCs的DNA合成和细胞增殖;应用半定量RT-PCR分析发现,在自发性高血压大鼠的肾和VSMCs中,AdM mRNA水平较低。

In present study, the model of the low shear stress in carotid or hypertension was established by the ligation of partial distal branches of the left common carotid or the coarctation of aorta in SD rats respectively. In some rats the low shear stress in carotid was accompanied by the hypertension. The media and intimal thickness, as well as the ratio of vessel thickness to inner diameter were determined by morphometrical approach.

本文通过腹主动脉缩窄、结扎左颈总动脉的部分分支建立了高血压、左颈总动脉低切应力、以及高血压伴有低切应力大鼠动物模型;几何形态学方法观测左颈总动脉的壁厚及壁厚/内径比的变化;金属蛋白酶谱法分析MMP-2活性;免疫印迹法检测信号通路分子p-Akt、p-38分子以及Rho GDIα的表达变化。

Hese abnormalities may be factors contributing to benign arteriolar nephrosclerosis due to primary hypertension .

GF-β1及PAI-1在高血压性肾损害的发生和发展过程中起着重要作用,可能是高血压性肾损害的发病机制之一。

He Relationship between Ang Ⅱ, TGF-β1, PAI-1 and Benign Arteriolar Nephrosclerosis Due to Primary Hypertension

GF-β1,PAI-1,AngⅡ与高血压性肾损害关系的研究论文标题:TGF-β1,PAI-1,AngⅡ与高血压性肾损害关系的研究

Whether the application of oxygenised liquid during surgery had protective effects on neurocyte in the patients with hypertensive cerebral haemorrhage?

背景:在高血压脑出血的治疗中,目前临床上应用多种方式改善机体缺氧,术中应用携氧液是否对高血压脑出血患者神经细胞有保护作用?

Objective: Determination the neurotension content through the hypertension patients acupuncture treatment union pharmacotherapy around,further discusses the acupuncture treatment union pharmacotherapy to treat the action mechanism ofhypertension.

目的:通过测定高血压患者针药结合治疗前后神经降压素的含量,进一步探讨针药结合治疗高血压病的作用机理。方法:将75例患者按入院先后顺序随机分为2组:针刺加药物组45例及药物组30例,观察治疗前后神经降压素的变化情况。

Neurovascular decompression moderates the pulsatile compression, and is to be a new method for the treatment of essential hypertension, especially for refractory hypertension.

神经血管减压术缓解了这种搏动性压迫,为原发性高血压尤其难治性高血压及有严重并发症的患者提供一种新的治疗方法,并已取得较好疗效。

vWF and Ps are involved in acute cerebral infarction, hepertension and diabetes mellitus,The result suggested that the contents of vWF and Ps play an important role in the development of acute cerebral infarction, The study of vWF and Ps in molecular biology is important in outbreaking mechanism of acute cerebral infarction, making a diagnose and giving treatment.

急性脑梗死、高血压、糖尿病患者vWF、Ps表达上调,说明vWF、Ps参与了急性脑梗死、高血压、糖尿病的病理过程,因此,vWF、Ps的增高,在急性脑梗死的发生和发展过程中起着重要作用。

It shows that, as one of the major new medical treatments, oxygenous exercise is especially suitable for the critical and light or medium high-blood pressure patients.

表明 :有氧运动作为一种非药物性治疗的主要方法之一,尤其适用于临界高血压和轻中度高血压患者。

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