高血压

"A particularly interesting finding of this study is that the vaccine achieved fairly good control of blood pressure in the early morning hours," said Juerg Nussberger, M.D., Division of Angiology and Hypertension, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, who presented the study in a Tuesday media briefing.

Juerg Nussberger博士认为与降压药物相比，高血压疫苗具有以下优势：（1）降压药物半衰期短，无法稳定控制清晨血压，而这正是高血压疫苗所擅长的；（2）高血压疫苗只需每四周注射一次，依从性明显好于降压药物；（3）高血压疫苗可有效控制血压，而降压药物只能使四分之一的患者血压得到成功控制。

Firstly, based on literature review and qualitative surveys, the modified risk factors that affecting the effect of hypertension management in the underdeveloped rural area were identified, the specific questionnaire and SIPHF were developed, and the first cross-sectional study was conducted. Secondly, the surveyed population were then divided into intervention group and control group, and periodic health education and following up were conducted to the intervention group for six months; Thirdly, the second cross-sectional study was conducted to evaluate the effect of intervention by qualitative and quantitative survey, the indicators include the knowledge awareness rate and the right belief rate for hypertension control, and the behavior prevalence related to hypertension intervention, the disease burden, the life quality and clinical outcomes resulted from hypertension, the dynamic tendency of blood pressure and the patients\' satisfaction. And the factors related to the effect of hypertension management was evaluated; Finally, SWOT analysis was conducted to evaluate the factors affecting the intervention process and effect, based on the results of qualitative and quantitative surveys on the factors related to effect of the intervention, and to provide evidence-based suggestions for SIPHF improvement and policy-making in the underdeveloped rural area in China.

首先，在文献综述和定性调查的基础上，确认影响欠发达地区农村高血压患者管理效果的因素，设计调查问卷和高血压管理方案，并开展第一次横断面调查；其次，将调查乡镇分为试验组和对照组，对试验组患者开展健康教育和定期的随访管理，对照组患者则按常规工作对待；第三，实施规范化管理6个月后，采用定量调查和定性访谈等方式评价管理效果，通过第二次横断面调查，对试验组与对照组干预前后的危险因素变化情况及干预效果进行评估，评估内容包括患者的知识、信念和行为等与高血压防治有关的危险因素指标，及其产生的疾病负担、生活质量、临床指标、血压水平变化趋势、干预组满意度等结果指标，并分析影响高血压干预效果的因素；最后，采用SWOT分析，根据定性和定量调查结果分析该类地区今后全面开展该项工作所面临的内部和外部环境因素，并为欠发达地区农村高血压规范化管理方案完善及政策制定提供循证建议。

The current study was conduct to analyze the distribution characters of single nucleotide polymorphisms 1166A/C of AT1R gene, and to investigate the association between AT1R gene SNP and essential hypertension and hypertensive left ventricular remodeling in Chinese Souther...

本课题旨在研究AT1R基因1166A/C单核苷酸多态性在中国南方汉族人群的分布特征及其与高血压病及其左室重构的关联关系，以期从分子水平探讨高血压发病和预后的机制及特点，为高血压病及其重要靶器官损伤遗传易感基因的识别和高血压病的防治提供科学依据。

Objective To explore the clinical significance between plasma levels of high-sensitive C reactive protein and atherosclerosis in patients with essential hypertension.Methods By measuring hs-CRP,endothelin,homocysteine,lipid and caroid artery echocardiography,ninety patients were divided into three groups equally,among them,the first group suffered 1-2 degree essential hypertension;the second group suffered 3 degree essential hypertension;excluding hypertension,coronary heart disease,diabetes,infections disease and tumour,control group as a third group was analyzed.

目的 对不同程度的原发性高血压患者进行血浆高敏C-反应蛋白（C-reactive protein，CRP）检测，探讨超敏C-反应蛋白在动脉粥样硬化疾病中的临床意义方法对30例1～2级原发性高血压患者(第1组)和30例3级原发性高血压患者(第2组)进行hs-CRP、内皮素、同型半胱氨酸和血脂检测、颈动脉超声检查，与除外原发性高血压、冠心病、糖尿病以及各感染、肿瘤患者进行比较分析。

Our country estimates that appointment has 100 million hyperpietic , new hair case makes an appointment with 4 million every year , the hypertension cause of disease does not understand in most patient,above to be being called primary hypertension , to be taking up general hypertension 95%.

医学论文摘要。中译英！十万火急！非常感谢！我国估计约有1亿高血压患者，每年新发病例约400万，在绝大多数患者中，高血压的病因不明，称之为原发性高血压，占总高血压着的95％以上。

Objective To study the change of cardiac functions in hypertensive patients complicated with obˉstructive sleep apnea syndromeand those without OSAS.Methods To observe30hypertensive patients comˉplicated with OSAS and28hypertensive patients without OSAS.24h dynamic blood pressure monitoring,left ventricular function by echocardiography and polysomnography were measured.The left ventricular function was compared between two groups.

目的 通过超声心动图检查高血压并阻塞性睡眠呼吸暂停综合征患者的左心室功能，并与单纯高血压患者的左心功能比较，以探讨高血压并OSAS患者的心功能的改变方法选择30例高血压合并OSAS患者和28例单纯高血压患者，全部病人完成动态血压、心脏B超及睡眠呼吸监测等检查，并进行两组资料对比分析。

Methods 42 people were selected from 2000 people who have taken healthy examination,with hypertension history、coronary artery disease,brain angiopathy,prostatomegaly、hepatitis、chronic bronchitis、diabetes and gastroenteritis,etc.and their history excluded.

高血压是以体循环动脉压升高为主要表现的临床综合征，分为原发性高血压和继发性高血压，在高血压患者中前者占95%以上，后者不足5%。

Renal hypertension is the mean reason of secondary hypertension , which accoutered for 10 of hypertension .

肾性高血压是继发性高血压最主要的原因，占高血压总数约10%，在临床治疗中较原发性高血压常更难以控制。

Results: The rate of abnormal increase of telomerase activity was 75.71%, pos itive rate of telomerase was 31.41%,OD value was 388.21(×10-3) in hypertension group（70 cases） were significantly increase (P＜0.01,＜0.0 5,＜0.01),comp ared with 47 cases' normal group(RAITA was 31.79%,PRT was 6.38%,OD value was 7 0.7).The difference of RAITA was not significance (P＞0.05) between aged h ypertension group (73.68%) and normal group(52.63%),the difference of RAITA w as significance (P＜0.05) between adult(age＜60) hypertension group (7 5.00%) and normal group(17.81%). The difference of RAITA、PRT was no signific ance among 2 groups of hypertension, and was significanceP＜0.05）among 2 g roups of normal.

结果：高血压病组（70例）端粒酶活性异常增高率（75.71%），阳性率（31.41%），OD值［388.21(×10-3)］分别明显高于正常组（47例）的 31.79%、 6.38%、70.7( P＜0.01，＜0.05，＜0.01)；老年高血压组的端粒酶活性异常增高率(73.68%)与正常同年龄组的52.63%比无明显差异，但成年（＜60岁）高血压组的端粒酶活性异常增高率(75.00%)较正常组的17.81%明显增加(P＜0.05)；高血压2个年龄组的端粒酶活性异常增高率、阳性率、OD值无明显差异，但正常人2年龄组这些参数有明显差异（P＜0.05）。

The main results are:(1) The cumulate cause-effects model was demonstrated at both macro and micro level data. The problem of data fitting of hypertension prevalence data was solved well enough with the cumulate cause-effects model. The parameters of the model were meaningful for the practice.(2) Taking the hypertension developing speed as an indicator of health equality of hypertension between urban and rural residents in China and discovered the macro level determinants of it.(3) The causal network was testified by the structure equation model.(4) It is found that the major determinants of hypertension prevalence in China is population ageing, overweight, lifestyle changing due to high economic developing speed and the lagging behind of health education.

主要的研究成果有：(1)首次观测到我国高血压的患病率曲线符合累积风险效应模型，解决了高血压患病率资料数据拟合中长期存在的方法学问题，并对模型中参数的实际流行病学意义给出了合理的解释，能够对疾病的发病率进行间接的估计；(2)提出了用高血压的发展速度作为衡量我国城乡高血压造成的健康不平等的重要指标，解决了我国高血压患病率评价中长期存在的一些错误性认识，揭示了我国高血压城乡发展不平衡的宏观决定因素；(3)利用结构方程模型对构建的网络模型进行拟合分析，证明了模型的有效性；(4)揭示了目前影响我国高血压发展趋势的决定因素，主要包括人口老龄化趋势加剧、超重人口比例增加、经济的快速发展带来生活方式的转变和健康教育的相对滞后等几个方面。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。