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高脂血症

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The animal tests indicated that: the levels of plasma and hepatic LPO were elevated in the rats with hyperlipidemia and hypercholesterolemia and at the same time, the red blood cell osmotic fragility and the concentration of SGPT were also in- creased; when the α-Toc was given, the LPO levels of serum and hepar could be de- pressed, the RBCOF and the level of SGPT were reduced too, which suggessted that the membranes of RBC and hepatic cells might be damaged by LPO.

动物实验表明,具有高脂、高胆固醇血症的大鼠血清、肝组织的LPO亦增高,同时红细胞渗透脆性,SGPT也增高,给予α-Toc可以降低血清和肝组织LPO的浓度,RBCOF,SGPT也下降,提示LPO可能引起了红细胞和肝细胞膜的损害。

Objective: To investigate the efficacy of atorvastatin combined with ezetimibe in the treatment of patients with hypercholesterolemia.

目的:观察联合应用阿托伐他汀与依折麦布治疗对严重高胆固醇血症患者的降脂疗效。

Diagnostic standard of MS by international diabetes federation makes the waist circumference as the main diagnostic condition,which showed that neurohumor immunological disorder resulting from abnormality of lipid factors secreted by lipocyte in accumulated fat of internal organs maybe the common pathophysiological basis of Ms and hyperuricemia.

国际糖尿病联盟在MS的诊断标准中将腹围作为主要诊断条件,提示内脏脂肪蓄积引起脂肪细胞分泌脂性因子异常造成的神经体液免疫紊乱可能是高尿酸血症以及MS共同的病理生理学基础。

Thus, we have demonstrated that in response to a HFD, brain GLP-1 signaling induces hyperinsulinemia and insulin resistance and decreases energy expenditure by reducing metabolic thermogenesis and ambulatory activity.

因此,我们认为脑中的GLP-1信号诱导的高胰岛素血症、胰岛素抵抗和能量消耗的降低(通过减少代谢产热和基础活动)是对高脂饮食的一种适应。

the coronary heart disease exist the insulin resistance, hyperinsulinism and lipin metabolism abnormity, they are all the dangerous factor which the coronary heart disease occurs, the insulin resist and the coronary heart disease clinical symptom serious degree are related.

冠心病存在胰岛素抵抗、高胰岛素血症及脂质代谢的异常,它们都是冠心病发生的危险因素,胰岛素抵抗与冠心病临床症状的严重程度相关。关键词:冠心病;胰岛素抵抗;血脂

VLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

ConclusionsVLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

结论VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg·kg-1·d-1) and ethambutol(250 mg·kg-1·d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠,随机分成正常对照组(12只)和模型组(48只),模型组给予高脂高糖饲料餵养6周,6周后再用腺嘌呤〔100 mg/kg·d)〕加乙胺丁醇〔250 mg/〕灌胃2周,造成胰岛素抵抗并高尿酸血症的大鼠模型。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg.kg-1.d-1) and ethambutol(250 mg.kg-1.d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠,随机分成正常对照组(12只)和模型组(48只),模型组给予高脂高糖饲料喂养6周,6周后再用腺嘌呤〔100 mg/kg·d)〕加乙胺丁醇〔250 mg/〕灌胃2周,造成胰岛素抵抗并高尿酸血症的大鼠模型。

Hyperglycemia and high free fatty acid level synergistically impair insulin secretions to cause ketone overproduction in high fat-fed obese rats.

高血糖与高FFA血症协同作用可严重损害高脂肥胖大鼠胰岛β细胞的胰岛素分泌功能,导致酮体生成显著增加。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。