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Objective To study the effect of iodine deficiency or excess upon the function of reproduction in Wistar rats.

目的 探讨低碘和高碘所致的甲状腺功能低下对大鼠生育力的影响。

According to these data authors considered that the mechanism of iodine-excess goiter probably different ...

作者认为,高碘甲状腺肿的发病机理与低碘甲状腺肿可能是不同的。

High iodide intake may aggravate patient's clinical symptoms such as thyrocele and ophthalmopathy, but there is no relation between level of UI and thyroid function .Improper iodine supplement to AITD patients may strengthen the immune function disorder .The abnormal increase of cytokine IL-1? and expression of CD80、 HLA-DR on PBMC may involve in the mechanism.

高碘可能加重了AITD突眼、甲状腺肿大等症状,但与甲状腺功能状态没有明显关系;本研究还提示对AITD不适当的补碘可能会导致甲状腺局部乃至全身的免疫功能失调,IL-1β等细胞因子和PBMC表达的HLA-DR、CD80异常与高碘导致的免疫紊乱可能有一定关系,值得进一步探讨。

The results showed polymeric diaryliodonium salts were effective aryl ion transfer reagents. Thirdly, a new type polymer supported hypervalent iodine reagents poly { [4-Hydroxy iodo] styrene} has been developed. It was an effective oxidative reagent, and could be applied to the one pot synthesis of 4-arylthiazoles.

然后,我们以聚苯乙烯羟基对甲苯磺酰氧基碘苯为原料,成功制备了一类新型聚合物高碘试剂—聚苯乙烯负载的炔基碘盐,并研究了其作为炔基转移试剂的有效性:(1)该试剂可对硫、氮、硒等负离子进行亲电炔基化反应,合成炔基亚砜、0,0-二烃基二硫代磷酸炔基酯、1-苯乙炔基苯并噻唑以及炔基硒醚。

The following conclusions have been gotten from a large amount of experiments and determinations: Triiodide, pentaiodide, heptaiodide, nonaiodide, undecaiodide of solid tetra-n-butyl ammonium polyiodides and tetrabutyl ammonium bromide polyiodides can be synthesized by solid phase process which is a economic easy way, while its not suitable for synthesizing solid tetramethyl ammonium polyiodides; Solution polyiodides of triiodide, pentaiodide can be synthesized through the complexation process, and TX-10 is a better complexing agent; Triiodide, pentaiodide, heptaiodide resinic polyiodides were synthesized by ion-exchange of resinifying process, and that is a viable easy way.

在大量实验和分析的基础上,可得到以下结论:用固相法可以合成出碘三、碘五、碘七、碘九和碘十一形式的正四丁基多碘化铵固体高聚碘和四丁基多碘化溴化铵固体高聚碘系列化合物,是制备高聚碘的经济、方便的合成方法,但此法对合成四甲基多碘化铵固体高聚碘系列化合物并不适用;TX-10是合成溶液高聚碘较佳的络合剂,通过其络合作用可以合成出碘三和碘五形式的溶液高聚碘;采用树脂法,通过离子交换,合成出了碘三、碘五和碘七形式的树脂高聚碘,此法简单可行。

The electric conductivity of solid polyiodides increases largely as the aggrandizement of polyiodide anions"polymerization degree. The solid polyiodides have excellent sterilizing effects and the effect of tetra-n-butyl ammonium undecaiodide is the best of them, and the sterilizing effects increase as the aggrandizement of polyiodide anions" polymerization degree. The sterilizing effects of resinic polyiodides increase as the aggrandizement of polyiodide anions polymerization degree, the heptaiodide resinic polyiodide has better sterilizing effects than the triiodide and pentaiodide.

固体高聚碘系列化合物的电导率随着高聚碘阴离子聚合度的增加而增加,并且增幅较大;固体高聚碘对常见细菌均具有很好的杀灭作用,并且随着高聚碘阴离子聚合度的增加,杀菌能力也随着增强,其中正四丁基十一碘化铵杀菌剂的效果最佳;树脂高聚碘随着高聚碘阴离子聚合度的增加,杀菌能力增强,碘七树脂高聚碘的杀菌效果要明显好于碘三树脂和碘五树脂高聚碘。

In solid phase process, the polyiodides, which include triiodide, pentaiodide, heptaiodide, nonaiodide and undecaiodide tetra-n-butyl ammonium iodide, tetrabutyl ammonium bromide and tetramethyl ammonium iodide poly-compounds, were synthesized by the low-heat solid phase reaction between iodine and tetra-n-butyl ammonium iodide, tetrabutyl ammonium bromide or tetramethyl ammonium iodide; In complexation process, solution polyiodides were synthesized by complexing action of different agents; In resinifying process, triiodide, pentaiodide, heptaiodide resinic polyiodides were synthesized by ion-exchange when the strong basicity styrene anion exchange resin, potassium iodide and iodine were used as raw materials.

固相法是用正四丁基碘化铵、四丁基溴化铵或四甲基碘化铵分别与碘作用,通过低热固相反应,合成出碘三、碘五、碘七、碘九和碘十一形式的正四丁基碘化铵、四丁基溴化铵或四甲基碘化铵的系列高聚碘化合物;在络合法合成溶液高聚碘的实验中,选用几种络合剂通过络合作用首次合成了溶液高聚碘;树脂法合成高聚碘的实验是采用强碱性苯乙烯系阴离子交换树脂、碘化钾和碘为原料,通过离子交换,合成了碘三、碘五和碘七形式的树脂高聚碘。

Iodine levels increase from lignite through subbituminous coal and bituminous coal to anthracite,it indicates that coal adsorbed excess iodine from the hydrothermal fluids during the process of metamorphism,including geothermal metamorphism and telemagmatic metamorphism.

从褐煤、亚烟煤、烟煤到无烟煤,碘的含量越来越高,表明在变质作用(含深成变质作用和区域岩浆热变质作用)过程中煤吸收了热液流体中的碘。

The iodine deficiency was corrected by the supplementation of iodized salt,however ,higher and lower intake of iodine all existed among the patients with thyrocele and hyperthyroidism .

合理补充碘盐能够纠正重庆市居民的碘缺乏状态,目前重庆市处于低碘性甲状腺肿伴甲亢和高碘性甲状腺肿伴甲亢的并存状态。

Results: The mean UI in Chongqing district were higher than proper iodide standard defined by international Council for control of iodine deficiency disorders,and the UI in HT groups were significantly increased compared with Con(P.05). The thyrocele and ophthalmopathy in AITD became more and severer accompanying UI increasing, the rate of goiter and endocrine ophthalmopathy in high iodide AITD was significantly higher than PI AITD( P.05).In the meantime, the positive percentage of TGAb and TPOAb also increased evidently in HI compared with PI(P.05).Cytokine IL-1?

结果:三组患者的平均UI水平高于国际碘缺乏理事会规定的适碘范围,HT患者的UI水平较正常人显著升高(P.05);在AITD患者UI水平的升高伴随着甲状腺肿大、眼部并发症等临床症状的加重,高碘组与适碘组相比差异有显著性(P.05),且随着UI水平的提高,TGAb和TPOAb阳性百分率明显提高,不同UI水平各组间和每两组间有显著差异(P.05)。

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