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Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer

采用免疫组织化学染色方法检测88例结肠癌组织中Livin，Caspase3 及MTA1的表达情况。结果（1）结肠癌组织中Livin的阳性表达率显著高于癌旁组织，且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（2）结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织，且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。（3）结肠癌组织中MTA1的阳性表达率显著高于癌旁组织，且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（4）Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论（1）Livin在结肠癌组织中过表达，它可能是促进结肠癌发生的重要因素之一。（2）Caspase3蛋白在结肠癌组织中表达被抑制而降低，且与Livin的表达呈负相关。因此，抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。（3）MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。

As a whole,the notable characteristic of primary productivity in size-fractioned structure was that nanoplankton occupied comparatively significant advantage in Beibu Gulf.Nanoplankton has the largest contribution to gross primary productivity,and picoplankton was the secondary contributor,while microplankton the least.The contribution of microplankton for primary productivity in the north Gulf was more than that in the other waters.Nanoplankton and picoplankton contribute more to the gross primary productivity in offshore deep waters than in inshore shallow waters3.The Beibu Gulf can be divided into three ecoregions:Region-Ⅰis the ecoregion in inshore shallow waters of the north Gulf.In average,the water depth is 18m,DIN is 1.88μmol/L,DIP is 0.20μmol/L,N:P is 9.4:1,dissolved silicate is 5.17μmol/L,the Chl a conentration in surface layer is 2.27mg·m~(-3),the assimilation index in surface layer is 3.80mg/,the primary productivity is 198.78mgC/(m~2·d), and potential fishery production is estimated to be 0.24gC/(m~2·a) according to the primary productivity.The ecoregion is mainly affected by the northern coastal water systems,and may be fit for aquaculture;Region-Ⅱis the ecoregion in offshore deep waters of the north Gulf and the coastal shallow waters to the west Hainan Island.In average,the water depth is 35m,DIN is 2.01μmol/L,DIP is 0.18μmol/L,N:P is 11.2:1,disovled silicate is 4.23μmol/L,the chlorophyll a of surface layer concentration is 1.45mg·m~(-3),the assimilation index of surface layer is 4.12 mg/,the primary productivity is 276.60mgC/(m~2·d),and the estimated potential fishery production is 0.34gC/(m~2·a) according to the primary productivity. The ecoregion was mainly influenced by ocean current from the South China Sea, rivers in the west coast of Hainan Island and the water from Qiongzhou Strait.It may be fit for aquaculture and fishery;Region-Ⅲis the ecoregion in offshore deep waters of the mid and south Gulf.In average,the water depth is 75m,DIN is 0.77μmol/L, DIP is 0.15μmol/L,N:P is 5.1:1,disovled silicate is 3.05μmol/L,the chlorophyll a of surface layer concentration is 0.70mg·m~(-3),the assimilation index of surface layer averaged is 3.69mg/,the primary productivity is 350.89mgC/(m~2·d),and the estimated potential fishery production is 0.43gC/(m~2·a) according to the primary productivity.The ecoregion was mainly affected by the circulation inside Beibu Gulf, and may be fit for fishery.

初级生产力的粒级结构的一个显著特点是总体上微型浮游生物在全调查海区均占较明显优势，对总初级生产力的平均贡献最大；微微型浮游生物对初级生产力的平均贡献次之；小型浮游生物对总初级生产力的平均贡献最小；湾北部小型浮游生物对初级生产力的平均贡献高于湾中部和湾南部，而湾中部和湾南部微型和微微型浮游生物对初级生产力的平均贡献高于湾北部，远岸深水区高于近岸浅水区。3、北部湾可以分为三个生态区：湾北部近岸浅水区，该区的环境主要特点是平均水深19m，DIN浓度平均值为1.88μmol/L，DIP浓度平均值为0.20μmol/L，N：P为9.4：1，硅酸盐浓度平均值为5.17μmol/L，表层叶绿素a平均值高达2.27 mg·m~(-3)，表层同化指数平均为3.80 mg/，初级生产力平均值198.78mgC/(m~2·d)，根据初级生产力计算潜在渔业资源碳生产量平均为0.24 gC/(m~2·a)，该区主要受湾北部沿岸水系影响，适合作为水产养殖区；湾北部深水区和海南岛西部沿岸浅水区，该区的环境主要特点是平均水深35m，DIN浓度平均值为2.01μmol/L，DIP浓度平均值为0.18μmol/L，N：P为11.2：1，硅酸盐浓度平均值为4.23μmol/L，表层叶绿素a平均值1.45 mg·m~(-3)，表层同化指数平均为4.12mg/，初级生产力平均值276.60 mgC/(m~2·d)，根据初级生产力计算潜在渔业资源碳生产量平均为0.34 gC/(m~2·a)，该区主要受南部湾口区海流向湾内延伸，沿岸海南岛河流注入湾内和琼州海峡过道水的影响，适合作为渔业作业区和水产养殖区；湾中部和南部远岸深水区，该区的环境主要特点是平均水深75m，DIN浓度平均值为0.77μmol/L，DIP浓度平均值为0.15μmol/L，N：P为5.1：1，硅酸盐浓度平均值为3.05μmol/L，表层叶绿素a平均值0.70 mg·m~(-3)，表层同化指数平均为3.69 mg/，初级生产力平均值350.89 mgC/(m~2·d)，根据初级生产力计算潜在渔业资源碳生产量平均为0.43 gC/(m~2·a)，该区主要受北部湾环流影响，适合作为渔业作业区。

The results showed that indoor air pollution by CO,NOx,and TSP washeavy in olb darracks with coal stoves in winter,but SO2 concentration was within standard in winter and summet.

结果表明，三市上述六项指标夏季大多在标准以内；冬季CO、NOx、CO_2、总悬浮颗粒物均超过标准，苯并芘冬季高于夏季，室内高于室外，旧营房高于新营房；以沈阳大气质量指数评价夏季哈尔滨新营房属"清洁"，余为轻污染，冬季哈尔滨新营房为轻污染，其余新营房为中污染，长春与锦西旧营房为极重污染。

Results A total of 9 patients were found have N3 disease on mediastinosopy, with cancer-cell- positive lymph nodes in the contralateral mediastinum in 6 and 3 in the right scalene.

统计学分析显示，肺腺癌组的N3发生率高于非腺癌组（P〈0.05），血清CEA水平升高组的N3发生率高于正常组（P〈0.05），同侧纵隔淋巴结多站转移组的N3发生率高于同侧单站转移组（P〈0.05）。

Freshman low income students in dealing with the problems on the score was significantly lower than sophomore, junior and senior low income students, and the self-condemned, was significantly higher than that of sophomore, junior and senior poor students; senior low income students SCL-90 in the interpersonal sensitivity, anxiety, hostility, paranoia and mental illness, as well as scores were significantly higher than those on the junior poor students, and obsessive-compulsive disorder in the sophomore and senior poor students were significantly higher than those freshman students , on the whole, a senior health poverty level of the mental health was significantly lower than the other three-year low income poverty students.

大一贫困生在应对方式解决问题上得分显著低于大二、大三、大四的贫困生，而在自责因子上显著高于大二、大三、大四贫困生；大四贫困生在SCL-90的人际关系敏感度、焦虑、敌对、偏执、精神病症以及总分上均显著高于大三贫困生，另外在强迫症上大二、大四贫困生均显著高于大一学生，总体上大四贫困生的心理健康水平显著低于其他三个年级的贫困生。

UA of blood of group of model Ⅰ,Ⅱ is elevatory (P.01), and UA of serum of group of Ⅰ of model of; of above of tenability 48 H is in 6, 24, 36, 48 H all group of Ⅱ of prep above model, model Ⅱ group is in 24, 36, group of Ⅲ of model of 48 H prep above (value of UA of serum of group of Ⅲ of model of P.05,.01); is in after building a model 6, 12, 24, 36 H apparent prep above contrasts group (P.01), it is normal that 48 H restores to come.

模型Ⅰ、Ⅱ组血UA升高(P.01)，且可维持48 h以上；模型Ⅰ组血清UA在6、24、36、48 h均高于模型Ⅱ组，模型Ⅱ组在24、36、48 h高于模型Ⅲ组(P.05、。01)；模型Ⅲ组血清UA值在造模后6、12、24、36 h明显高于对照组(P.01)，48 h恢复至正常。

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p＜0.05/p＞0.05),sod was lower than model group(p＜0.001) and was higher than control group(p＜0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响，探讨其治疗阿尔茨海默病(alzheimer disease，ad)的作用机制。方法用冈田酸(okadaic acid，oa)注射大鼠侧脑室造模，测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p＜0.001)，高于对照组(p＜0.05)；sod高于模型组(p＜0.001)和对照组(p＜0.05)；mda低于模型组(p＜0.001)，高于对照组(p＜0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性，降低mda蓄积和tau蛋白生成，具有防治阿尔茨海默病的作用。

Results Fetal Macrosomia group: the rate of obesity is 9.4%, obviously higher than that of the contrast group, 2.03%(χ2=7.4715,P.01), the rate of overweight is 19.4%, higher than that of the contrast group, 3.3%（χ2=18.9434,P.01）;Fetal Macrosomia group: there is a remarkable difference in GLU, ALT, HDL, Insulin, and APN,（P﹤0.05~0.01）,There were marked differences in the aspects of body mass index, the level of blood grease,HDL, ALT, HOMA-IR, adiponectin（P.05~0.01） Conclusion: In adolescence of Fetal Macrosomia weight index, GLU, Insulin and ALT are obviously higher than that of the contrast group; the HDL ,and APN which has great protective effect to angiosclerosis is also absolutely lower than the compare group.

结果：巨大儿组：肥胖率为9.4%，明显高于对照组2.03%（χ2=7.4715，P.01）、超重率为19.4%，高于对照组的3.3%（χ2=18.9434，P﹤0.01）；巨大儿组：血糖、转氨酶、高密度脂蛋白、胰岛素、脂联素方面有显著差异，（P﹤0.05~0.01），结论：巨大儿在青少年期，其体重指数、血糖、胰岛素、转氨酶水平明显高于对照组，对动脉硬化有保护作用的高密度脂蛋白、脂联素明显低于对照组。

DNA C-values might be one of important indices in the evaluation of angiospermous invasiveness. To test this viewpoint, we compared DNA 1C-values and basic genome sizes in 3,676 angiosperms. The results suggest that:(1) the two nuclear values vary greatly among different groups, e.g., significantly higher in herbs than in trees, in monocots than in dicots, in perennials than in non-perennials;(2) the two nuclear values both have significant effects on plant invasiveness, especially in herbs, dicots, monocots, perennials, non-perennials, diploids, polyploids, Compositae, and Poaceae, while not significant in trees and Fabaceae.

DNA C值与被子植物入侵性密切相关，为考察应用DNA C值评估被子植物入侵性的可靠性和局限性，我们统计分析了全世界范围内3676种被子植物的DNA 1C值（配子未发生DNA复制时的染色体DNA含量）及基因组大小（单个染色体组的DNA 含量），结果表明：1）DNA 1C值和基因组大小在被子植物不同类群中差异极大，例如在草本植物中显著高于木本植物，单子叶植物显著高于双子叶植物，多年生植物显著高于非多年生植物；2）两项指标都与被子植物入侵性显著负相关，尤其是在草本植物、双子叶植物、单子叶植物、多年生植物、非多年生植物、二倍体、多倍体、菊科和禾本科中，然而在木本植物、豆科植物中其与植物入侵性无显著关系。

Results showed that the root colonization rate of S. gracilis (62.2%) was higher than that of A. conyzoides (36.5%) and P.notatum (37.3%).The arbuscule percentage showed a similar pattern. Although the biomass and P content in the shoots of the three grass species were comparable, P content in S. gracilis roots was higher than that in A. conyzoides and P. notatum roots. The species richness and hyphal density in the rhizosphere soil of S. gracilis plants were less than those of A. conyzoides and P. notatum plants, while the spore density was highest for A. conyzoides and lowest for P. notatum. Diversity index of the native AM fungi in the rhizosphere soil of P. notatum plants was slightly higher than those of S. gracilis and A. conyzoides plants. PCRDGGE analysis was consistent with the morphological results.

结果表明，柱花草根系的侵染率(62.2%)显著高于百喜草(36.5%)和藿香蓟(37.3%)，丛枝率有相似的趋势；3种草地上部的生物量和含磷量没有差异，但是柱花草根系含磷量显著高于百喜草和藿香蓟；柱花草根际土壤中AM真菌的菌种丰度和菌丝密度均小于百喜草和藿香蓟，但是孢子密度大于藿香蓟而小于百喜草；藿香蓟根际土著AM真菌群落的多样性指数略高于柱花草和百喜草；PCR-DGGE分析结果与之吻合。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。