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YMDD mutation: HBV YMDD mutation were developed in 12 lamivudine recipients, whereas the treated group had no incidence of HBV YMDD variation, there were significant difference between two groups (p=0.000). YMDD mutation resulted in increase of the mean HBVDNA levels (p=0.000), but no contribution to serum ALT diversification (p>0.05). 2. Precore nt1896 mutation: Precore nt1896 mutation incidence had no difference between lamivudine recipients and objects who received combination therapy of Kidney-invigorating Granule and Marine Injection, and patients of HBeAg negative and HBeAg positive had a close incidence of precore mutation as well as. Precore nt1896 mutation had no influence on serum ALT level. The occurrence of precore nt1896 mutation contributed to serum HBVDNA load increased and worse response of HBVDNA extenuation. 3. HBV genotype: The baseline of serum HBVDNA gradually increase in turn of genotype B, genotype C and genotype B/C. Genotype B seemed to obtain higher rate of serum HBVDNA loss and HBeAg/anti-HBe seroconversion after combination therapy of Kidney-invigorating Granule and Marine Injection, differencing with lamivudine therapy.

疗效相关因素研究:1YMDD变异:对照组有12例检出YMDD变异,治疗组无1例检出,两组比较有显著性差异(P=0.000);发生YMDD变异者血清HBVDNA和ALT水平均有所升高,HBVDNA平均水平高于非变异者(P=0.000);血清ALT与非变异者无明显差异(P>0.05)。2前C区nt1896变异:前C区nt1896变异发生率在治疗组和对照组以及HBeAg阴性和HBeAg阳性患者之间均无明显差异(P>0.05);1896c变异对血清ALT水平无明显影响;治疗组发生1896c变异者,其HBVDNA平均水平较之未变异者明显升高(P<0.05),治疗后HBVDNA下降幅度明显低于未发生1896c变异者(P=0.000)。3HBV基因型:血清HBVDNA基础水平在B、C、B/C混合型间存在明显差异(P<0.05),按B型、C型、B/C混合型依次升高;治疗组HBVDNA阴转率、HBeAg/抗-HBe血清转换率,B型似乎高于C型和B/C混合型,但无统计学意义(P>0.05);对照组HBVDNA阴转、HBeAg/抗-HBe改变在B、C、B/C混合型间无明显差异(P>0.05)。

Prognostic significance of p27kip1, p45Skp2 and Ki67 expression profiles in Merkel cell carcinoma, extracutaneous small cell carcinoma, and cutaneous squamous cell carcinoma.

在我们的研究中,免疫印迹结果显示Skp2在HCC组织中的表达明显高于对应的癌旁肝组织,免疫组织化学结果也显示Skp2在HCC中表达显著高于癌旁肝组织及血管瘤旁肝组织。

Results Four patients had shortly ventricular extrasystole, ST segment depress and T wave inversion in groupⅠ; the parameter values kept statistically stabilization in group Ⅲ compared with groupⅠand groupⅡ.

结果:Ⅰ组插管后即刻、插管后2 min的SBP、HR和RPP值均显著高于雾化前基础值(P<0.01),SBP在插管后5 min仍高于基础值(P<0.05)。Ⅱ组插管后即刻SBP、HR和RPP与基础值比较明显增高(P<0.01或P<0.05)。

Results at the 3 hours point after the ovary excitation,the serum e2 level of foh ⅰ was significantly higher than that of the control group,while at the 8, 12, 18,24 hours point,the e2 level of foh ⅱ was significantly higher than that of foh ⅰ.the functional state and functional activity of aromatase had no difference among the groups.

结果 3?h时点foh ⅰ组e2水平显著高于对照组,而8,12,18,24?h时点foh ⅱ组e2水平则显著高于foh ⅰ组,但芳香化酶功能状态和活性在各时点差异均无统计学意义。

Furfur. At the same time, selected the culture supernatant. Used the whole-fat-cow"s-milk plate method, the Folin-phenol method and the QuantiCleave proteinase Assay Kit to test the proteinase activity of mycelial phase and yeast phase of M. furfur. The effect of temperature and pH on this assay was also evaluated.Result:①The whole-fat-cow"s-milk plate method: Seven days after inoculation, the proteinase activity of the mycelial phase supernatant (12.5 ± 1.2mm) is higher than that of the yeast phase (9.25±0.71mm)(p.05); With the passage of the inoculation time, the proteinase activity of the mycelial phase is rising; the temperature has no obvious effect on the proteinase

结果:①全脂牛奶平板法:培养第7天菌丝相上清液蛋白酶活性(12.5±1.2mm)高于酵母相(9.25±0.71mm)(p<0.05);菌丝相上清液蛋白酶活性随培养天数延长而增大;25℃和37℃两种温度对上清液蛋白酶活性无明显影响(P>0.05);②Folin-酚法:上清液蛋白酶活性随培养天数、菌落计数、菌丝诱导率增加而增大,培养液pH值呈下降趋势;同一天的菌丝相上清液蛋白酶活性明显高于酵母相(p<0.05);三种温度(25℃、37℃、49℃)及三种pH值(3.8、5.6、7.4)对上清液蛋白酶活性无明显影响;温度37℃、pH5.6时菌丝相上清液蛋白酶活性最高;③QuantiCleave蛋白酶试剂盒:菌丝相及酵母相上清液中均含有蛋白酶且

First quarter, AMD's gross margin was 43% higher than the previous quarter's 23 percent, up from 43 percent the same period last year.

2009年第一季度,AMD的毛利率为43%,高于上一季度的23%,高于去年同期的43%。

Yesterday, the Construction Bank H shares closed at 4.11 Hong Kong dollar, A shares closed at 4.55 yuan, were significantly higher than the Bank of America's holdings in this price.

昨天,建设银行H股在4.11港元封闭,A股收盘为4.55元,均显着高于美国银行在这一价格高于持有。

In this paper, the ""state-trait anxiety inventory"" was used to inquire and analyze the state and trait anxiety level of Shanghai hobbledehoy football players .The results of the research shows that the players' anxiety level from the different position on the court and the different level teams have a significance difference. The state anxiety of the fullback is higher than the midfield players; the trait anxiety of the midfield and fullback is higher than the forward.

本文采用"状态——特质焦虑量表"对上海市后备专业足球运动员的特质焦虑与状态焦虑水平进行了调查与分析,研究结果表明,不同场上位置以及不同水平球队专业足球运动员的焦虑水平存在显著差异,后卫的状态焦虑水平明显高于前卫;前卫与后卫的特质焦虑水平要明显高于前锋。

In the housing sector, and only slightly more than 48% of black households own their own homes, white families homeownership rate is higher than 75%.

在住房方面,只有略高于48%的黑人家庭拥有自己的住房,白人家庭的住房拥有率却高于75%。

Results:The early enteral feeding after burn injury was more effective to reduce the hypermetabolism response.The average of total urine nitrogen on PBD11,12,13,14 in EN were significantly lower than those of PN,REE on PBE4,8 in PN were significantly higher than that of EN.

结果:早期肠道营养明显降低严重烧伤高代谢,24 h尿氮排出在伤后11天后PN组明显高于EN组,伤后第4、8天PN组REE明显高于EN组。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。