髓鞘

Results: ApoD was observed positively expressed in type2 astrocytes and oligodendrocytes from O2A lineage, while it was not expressed in type1 astrocytes from T1A lineage. Accordingly, we can verify the phenomenon found in the study of T1A and T2A gene different expression profile that ApoD mRNA was highly expressed in T2A and lowly expressed in T1A. Conclusion: It can be concluded that lipid metabolism related genes such as ApoD play important roles in the generation and differentiation of O2A lineage, which closely correlate with internal mechanism of lipid metabolism in the brain and myelogenesis.［Key words］astrocyte(T1A, T2A); oligodendrocyte; O2A lineage; apolipoproteinApoD

我们已采用基因芯片技术在mRNA水平研究两型星形胶质细胞的基因表达谱差异，发现ApoD在2型星形胶质细胞中差异高表达，故本文拟用激光共聚焦双重免疫荧光标记技术进一步在蛋白质水平观察ApoD在体外分化成熟的两型星形胶质细胞以及少突胶质细胞中的表达情况，以期为我们深入研究ApoD等脂代谢相关基因在脑内脂质代谢和神经髓鞘发育机制中所起的作用提供有用的实验依据，依此探讨胶质细胞发生和分化的信号机制。

The neural histology shows that the degeneration, necrosis and reduction of the quantity of the neur cell on anterior horn cinereum, the change on lateral cord white matter demyelination, disorder, disruption of the neuraxon. The entire changes is in conformity with pathological character of the CSM.

神经组 织学检查见到灰质前角神经元的变性、坏死、数量减少，以及侧索白质脱髓鞘变，排列紊乱，轴突断裂，病理变化符合CSM 的病理变化特征。

METHODS: We performed neurological examination, neurophysiological, neuroimaging, and neuropathological studies on sural nerve biopsy in 10 hypomyelination and congenital cataract patients from 5 unrelated families.

我们进行神经系统检查、神经生理学、神经影像学和腓肠神经活检的神经病理学研究，这些是对来自于5个不相关家庭的10例先天性白内障和神经髓鞘形成不良患者进行的检查。

Changes of perfusion and metabolite ratios in inflammatory or demylinating lesions were different from oncologic diseases.

炎性／脱髓鞘病变的灌注及代谢物变化明显不同于肿瘤性病变。

The myelin sheath of regenerative nerve fibers in the experimental group is thicker and deeper after staining with osmate than the one in the control group.

与对照侧比较，实验则再生神经纤维的髓鞘较厚，着色较深。

Objective In order to understand the role of the immune function in the pathogenetic mechanism of multiple sclerosis.

多发性硬化的病因尚不完全清楚，但其自身免疫的发病机制已得到证实和公认，属于特异性抗原介导的细胞免疫和体液免疫共同参与的中枢神经系统炎性脱髓鞘病。

The pathological lesions in EAN are characterized by the perivascular infiltration of T cells, macrophages and demyelination in the PNS.

EAN的病理损害是以周围神经血管周围T细胞、巨噬细胞浸润和节段性脱髓鞘为特征。

He visited the neurology OPD and was diagnosed with anti-MAG neuropathy in 1995. Plasma phoresis replacement and an intravenous injection of immunoglobulin were given but in vain.

这是一位88岁男性荣民，主述因双下肢无力，手脚麻，至神经内科求诊，诊断为髓鞘糖蛋白抗体神经病变，做过血浆置换术及免疫球蛋白治疗，但效果不显著。

Objective To get information of current status in China by analyzing chronic inflammatory demyelinating polyneuropathy data.

目的 汇总临床及文献资料，了解中国地区慢性炎性脱髓鞘性多发性神经病的临床特征。

Judging from this clinical course, this case seems to be chronic inflammatory demyelinating polyneuropathy with acute onset.

从这一临床过程判断，本例可以诊为慢性炎性脱髓鞘性多发神经病急性发作。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。