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There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum(S1-S2) was involved firstly.There were 56 patients(average,37.7 years) diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma (17),Ewing′s sarcoma/PNET(14),multiple myeloma(12),lymphoma(6) and osteosarcoma(6) were found in 64 patients.

其中脊索瘤95例,男62例,女33例,平均年龄55.7岁,骶尾区疼痛是主要症状(82例),半数以上患者伴有坐骨神经痛,肿瘤多先累及低位骶骨(S3~S5);神经源性肿瘤76例,男36例,女40例,平均年龄47.7岁,神经纤维瘤43例,神经鞘瘤24例,恶性神经鞘瘤9例,主诉多为坐骨神经痛、会阴部麻木(36例)和无痛性包块(11例),20例患者为查体或其他原因检查时发现,67例骶骨良性神经源性肿瘤起源于S3以上神经者54例,起源于S3以下神经者3例,发生于骶前未累及骶管者10例;骨巨细胞瘤60例,男24例,女36例,平均年龄32岁,腰骶尾部不适(37例)、坐骨神经痛(21例)是主要的临床表现,肿瘤多先累及上位骶骨(S1~S2);骶骨其他原发良性肿瘤及瘤样病变56例,包括畸胎瘤、皮样囊肿、表皮样囊肿共24例;其他原发恶性肿瘤64例,包括软骨肉瘤17例,尤文肉瘤14例,多发性骨髓瘤12例,成骨肉瘤6例等。

In spina bifida the neural arch, usually in the lumbosacral region, is incomplete with secondary damage to the exposed neres.

脊柱裂通常是腰骶部的椎骨不完整,伴有暴露在外的神经损伤。

One-stage surgical management by posterior instrumentation and anterior resection plus interbody autografting is an effective method in dealing with lumbosacral spine tuberculosis.

一期后路内固定加前路病灶清除椎体间植骨融合术治疗腰骶段脊柱结核的疗效确切,能达到彻底清除病灶和重建腰骶稳定的目的。

In summary, the present study revealed that Barrington's nucleus and D-region received direct projection fibers from the sacral spinal neurons in lamina I, parasympathetic nucleus and dorsal commissural nucleus; periaqueductal gray also received afferent projections from the lumbosacral spinal cord and sent projection fibers to the Barrington's nucleus and D-region.

上述结果说明:大鼠腰骶髓 I 层、骶髓副交感核和后连合核神经元发出的投射纤维直接终止于 Barrington's 核和 D 区内;导水管周围灰质也接受来自腰骶髓的投射纤维,同时发出纤维终止于 Barrington's 核和 D 区内。

Therefore, in the present study, a retrograde and anterograde experiments were made in the rat to address this issue. After injection of cholera toxin B subunit, a retrograde tracer, into Barrington's nucleus or D-region, some retrogradely labeled neurons were found in lamina I, sacral parasympathetic nucleus and dorsal commissural nucleus of the lumbosacral spinal cord segments. Injection of biotinylated dextran amine into lamina I, sacral parasympathetic nucleus and dorsal commissural nucleus, respectively, a large number of BDA-labeled axon terminals were seen in Barrington's nucleus and D-region.

发现,将逆行示踪剂霍乱毒素 B 亚单位( Cholera toxin B subunit; CTb )注射到 Barrington's 核或 D 区后,在大鼠腰骶髓 I 层、骶髓副交感核和后连合核内分布有一定数量的 CTb 逆标神经元;将顺行示踪剂结合生物素的葡聚糖胺(Biotinylated dextran amine; BDA)分别注射到腰骶髓 I 层、骶髓副交感核和后连合核内后, Barrington's 核和 D 区内出现大量顺行标记的轴突终末。

It has been suggested that the architecture of the lower lumbar vertebrae and sacrum (e.g., inadequate separation between the inferior articular process of L4 and the superior articular process of L5, a wedged-shape interfacet region of L4, a more frontally oriented lumbar facet, and a wider sacrum), pelvic orientation and lumbosacral parameters (e.g., pelvic incidence, sacral table angle) may play a role in the development of spondylolysis.

低位椎体和骶骨的结构(如L4下关节突与L5上关节突间隔不足,L4下关节突成楔形,腰椎小关节方向过分偏额面方向,骶骨过宽),骨盆方向和腰骶段的参数(如骨盆影响和骶骨水平角)可能在脊柱滑脱的发展中扮演重要角色。

The lumbosacral subdural space is most commonly affected.

腰骶部的硬膜下腔是最常见的累及部位。

Nearly all of FOS expression was blocked by bilateral transection of the pudendal nerve, whereas bilateral transection of the pelvic nerve seemed to have no obvious effect on FOS expression.

双侧切断阴部神经几乎可完全阻断FOS在腰骶髓的表达,但FOS表达不受切断双侧盆神经的影响。

Erector spinae muscle fatigue was found after repetitively lifting and the forces at L5/S1 spinal joint were changed with various lifting technologies in volunteers simulating the lifting tasks in laboratory.

在实验室由健康人模拟造型作业中的搬举动作,结果重复搬举导致竖脊肌疲劳,而生物力学和动力学分析发现搬举姿势、搬举速度和负荷均影响脊柱腰骶关节的受力。

Results In healthy subjects, L2-L5 nerves were displayed clearly by MRN, with a round or ellipse ganglion of 3-6 mm in diameter, and smooth stick-like nerve root and trunk, 2-5 mm in diameter. The signal intensity was higher in ganglion than nerve root or trunk. 40% of nerve root sheath was surrounded by small amount of cerebrospinal fluid, Femoral nerve was displayed in all subjects, while only 83.3% of obturator nerve and 43.3% of lumbosacral trunk were manifested. Lamellar blurred hyper-signal intensity was seen around 80.9% of lumbar plexus in GBS, but none in CIDP.

结果 正常组MRN可清晰显示腰2~5神经的走行,神经节呈圆或椭圆形膨大,大小约为3~6mm,神经根及干呈条状、边缘光滑,大小约为2~5mm、神经节信号高于神经根和干,40%的神经根鞘有少量脑脊液,股神经、闭孔神经、腰骶干的显示率分别为100%、83.3%、43.3%。80.9%的GBS腰丛神经周围有片状模糊高信号,神经根和节大小和信号无明显改变,25%神经干增粗,50%的神经干信号增高,边缘模糊。

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