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骨髓细胞生成

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Objective To investigate the existence of the erythropoiesis inhibitors.Methods The present study included twelve undialyzed ESRD patients with anemia.

目的 本文采用甲基纤维素细胞培养的方法,分析尿毒症患者血清对小鼠骨髓红系祖细胞集落形成的影响,初步探讨红细胞生成抑制因子的存在。

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩,管壁增厚呈空虚网状,生精细胞层次减少,间质细胞增生,但仍见有精子生成;高剂量组可见到精子呈异型性改变,细胞核浓缩深染,且随着摄入时间延长改变愈趋明显;F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩,间质增生明显,20个月时肾小球萎缩纤维化;F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生,淋巴母细胞增生活跃,20个月时脾小体减少,生发中心稀疏;F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润,晚期骨髓有核细胞减少,脂肪细胞增加。

Objective To investigate the existence of the erythropoiesis inhibitors and the different effects of high-flux dialyzer and low-flux dialyzer on the clearance of EI.And to observe the effects of uremic patients sera and the ultrafiltrate from F80 and F6 dialyzer on CFU-E and BFU-E colony groewth of normal mice bone marrow.

目的 本文采用甲基纤维素细胞培养的方法,分析尿毒症患者血清及超滤液对小鼠骨髓红系造血祖细胞集落形成的影响,初步探讨红细胞生成抑制因子的存在、其相对分子质量大小及高通量透析器与普通低通量透析器对其清除的不同影响。

BACKGROUND: It is a debate of bone marrow mononuclear cells to promote the regeneration of infarcted myocardium.

摘要背景:关于骨髓单个核细胞促使梗死心肌再生存在很大争议,早期研究均认为非常有效,甚至可以分化为心肌细胞,但最近的文献却基本否认了这种说法,认为单个核细胞仅可以有限的促进血管生成。

BACKGROUND: Lipopexia induced by glucocorticoid is fat precipitation in marrow due to abnormal lipometabolism, or differentiation of cells resulting from hormone-affected bone marrow mesenchymal cells.

摘要背景:糖皮质激素引起的髓内脂肪蓄积是由机体脂肪代谢异常在髓内形成的脂肪沉淀,还是由于激素直接作用于骨髓间充质细胞使细胞发生了分化,以及具体生成的过程目前还没有定论。

BACKGROUND: Lipopexia induced by glucocorticoid is fat precipitation in marrow due to abnormal lipometabolism, or differentiation of cells resulting from hormone-affected bone marrow mesenchymal cells. The precise generating procedure remains unclear. OBJECTIVE: To investigate effects of various concentrations of dexamethasone on adipogenic differentiation of bone marrow mesenchymal cells.

背景:糖皮质激素引起的髓内脂肪蓄积是由机体脂肪代谢异常在髓内形成的脂肪沉淀,还是由于激素直接作用于骨髓间充质细胞使细胞发生了分化,以及具体生成的过程目前还没有定论。

Among the cases, hypergranular promyelocytic was present in 15%. Infected bone marrow and megaloblastic anemia were observed in 5% respectively. Fungi infected bone marrow and idiopathic thrombocytopenic purpura were found in 2.5% respectively. Pure red cell aplasia and granulocytic series deficiency due to regenerative granulocyte failure were observed in 2.5% respectively.

在40例艾滋病患者中,反应性早幼粒细胞增多者占15%,感染性骨髓象和巨幼细胞性贫血各占5%,真菌感染性骨髓象和特发性血小板减少性紫癜各占2.5%,纯红再障和生成减少性粒细胞缺乏症各占2.5%。

Objective To investigate the existence of the erythropoiesis inhibitors.Methods The present study included twelve undialyzed ESRD patients with anemia.

目的 本文采用甲基纤维素细胞培养的研究方法,分析尿毒症患者血清对小鼠骨髓红系祖细胞集落形成的影响,初步探讨红细胞生成抑制因子的存在。

Http://www.44dx.com Objective To investigate the existence of the erythropoiesis inhibitors.Methods The present study included twelve undialyzed ESRD patients with anemia.

http://www.44dx.com 目的本文采用甲基纤维素细胞培养的方法,分析尿毒症患者血清对小鼠骨髓红系祖细胞集落形成的影响,初步探讨红细胞生成抑制因子的存在。

Bone marrow derived fibrocytes migrate to the asthmatic airway from blood circulation acts as a progenitor cell of fibroblast and myofibrolast.

近来研究也发现,骨髓生成的纤维球扮演了纤维母细胞或肌纤维母细胞的前驱细胞角色,在特定细胞激素的引导下,由血流循环中移行至发炎的气道。

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