骨髓性白血病

Feverfew is an herbal medicine that is used to treat various aches and pains, including fever, arthritis and menstrual discomfort.

能够有针对性地消灭引发急性和慢性骨髓性白血病的干细胞，从根本上遏制疾病的发生。

Avian leukosis virus subgroup J ; IMC_（10200） strain ; experimental ; myeloid leucosis

J亚群禽白血病病毒； IMC10200株；实验性；骨髓性白血病

Herein, we report a case of priapism in a 24-year-old male caused by CML with presentation of very high leukocytes count of 387800/mm^3 and 29% blast cells.

在此，我们报告一例二十四岁男性因慢性骨髓性白血病引起的阴茎异常勃起症，用非常高数目的白血球达387800/立方公厘并29%的胚芽细胞来表现。

Low-flow priapism is a rare complication of leukemia resulting in hyperviscosity due to high leukocytes with leukostasis and is most frequently found in chronic myeloid leukemia.

低流量的阴茎异常勃起症为白血病罕见的并发症，是由於大量的白血球并白血球留滞而导致高黏稠性所造成的，最常见於慢性骨髓性白血病。

Tender, erythematous, edematous plaques that may centrally vesiculate on the upper part of the body associated with fever and leukocytosis characterize Sweet's syndrome.

身体上部压痛性水肿性红斑块伴发热和白细胞增多为Sweet综合征的特征，这可能是骨髓性白血病的早期征象。

Tender, erythematous, edematous plaques that may centrally vesiculate on the upper part of the body associated with fever and leukocytosis characterize Sweet's syndrome.

身体上部触痛、红斑块、水肿性斑块伴发热和白细胞增多为 Sweet 综合征的特征，这也可能是骨髓性白血病的早期征象。

The present study was undertaken to observe experimental myeloid leukosis induced with IMC_(10200) strain ALV-J which was isolated originally from a normal broiler breeder.

对分离自肉种鸡群亚临床感染的J亚群禽白血病病毒IMC10 2 0 0 株进行了实验感染诱发禽骨髓性白血病的病理学研究。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Acute myelocytic leukemia is a malignant neoplasm of hematopoietic cells characterized is an abnormal proliferation of myeloid precursor cells.

急性前骨髓性白血病，是一种造血组织的恶性疾病，其治病原因乃骨髓性前趋细胞不正常的大量增生，并有细胞分化停止的病变。

These have shown anti-tumor acticity in a number of human cancers , e.g. lymphomas ,myelomas , myelogenous leukemia and breast cancer .

这些都表现出抗肿瘤化性，在一些人类癌症，例如：淋巴瘤，骨髓瘤，骨髓性白血病，乳腺癌。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。