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As a member of TGF-β supergene family, bone morphogenetic protein-2 (BMP-2) acts mainly on the induction of dif...

骨形态发生蛋白-2(BMP-2)是TGF-β超基因家族的成员,其主要生物学作用是诱导未分化的间充质细胞分化形成软骨和骨。

As a member of TGF-β supergene family, bone morphogenetic protein-2 (BMP-2) acts mainly on the induction of differentiation of undifferentiated mesenchymal cells to form cartilage and bone.

骨形态发生蛋白-2(BMP-2)是TGF-β超基因家族的成员,其主要生物学作用是诱导未分化的间充质细胞分化形成软骨和骨。

RESULTS: The relative levels of COX2 mRNA as well as the contents of PGE2 and cAMP were elevated after fracture, and were significantly higher in study group than those in control group at 3 and 4 weeks postoperatively. Histological observation revealed that the mineralization of cartilage matrix, the endochondral bone formation and the callus remodelling took place earlier in study group.

结果:环氧化酶2(COX2) mRNA的表达量以及PGE2和cAMP的含量均较骨折前显著上升,且实验组在术后3~4 wk时以上指标明显高于对照组,组织学结果则显示实验组骨折间隙内软骨内成骨和编织骨向板层骨的改建均领先于对照组。

To be qualified as an EOS, the tumor must (1) arise in the soft tissue and not be attached to bone or periosteum,(2) have a uniform sarcomatous pattern ( to exclude the possibility of a mixed malignant mesenchymal tumor),(3) produce osteoid and/or cartilage matrix.

本病的诊断标准是(1)发生于软组织而与骨及骨膜部不相连;(2)具有一致的骨肉瘤表象,以排除混合性恶性间叶组织肿瘤;(3)可产生骨质或软骨样基质。

During the last few years a large amount of evidence has provided new insights into the biochemistry and molecular biology of cartilage, subchondral bone, and other articular tissues, which suggest distinct etiopathogenetic mechanisms in some forms of primary OA.

过去几年中的大量的证据,让我们在软骨,软骨下骨及其他关节组织的生物化学和分子生物学方面获得了新的认识,提示某些类型的原发性关节炎有不同的发病机制。

Severity of joint swelling, radioimmunoassay of serum estradiol (E 2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once we...

结果:切除卵巢的小鼠,血中雌二醇水平明显下降,而血清骨钙素和肿瘤坏死因子的含量则显著增加;同时,滑膜组织炎症加重,软骨损伤及骨的破坏均更为严重。

Methods: The mice for experiment were immunizied with subcutaneous injection of type Ⅱ collagen to induce arthritis after ovariectomy. Severity of joint swelling, radioimmunoassay of serum estradiol (E2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once weekly.

切除小鼠卵巢后,Ⅱ型胶原皮下注射以诱导关节炎;每周1次观察小鼠的关节肿胀程度;组织切片光镜下观察小鼠滑膜、关节软骨及骨的改变;放射免疫法检测小鼠血清雌二醇、骨钙素、肿瘤坏死因子的变化。

Results There was moderate or strong negative correlation among the indexes of the degeneration of intervertebral disc including the relative area of vascular bud, the ratio of the uncalcified and the calcified layer, the quantitation of collagen type Ⅱand the indexes of osteoporosis including the thickness ratio of cortical bone, the relative area of bone trabecula, the density of femoral bone and vertebral body bone, the max stress and straining of bone.

结果 骨质疏松相关指标骨皮质厚度指数、骨小梁相对面积、股骨密度、椎体骨密度与椎间盘退变指标终板血管芽相对面积、非钙化/钙化层比值、Ⅱ型胶原定量之间存在中度到强度的负相关,而与Ⅹ型胶原表达存在中度到强度的正相关,其中椎体骨密度与软骨终板的Ⅹ型胶原相关性最强。

Forty-sixe cases of symptomatic dynamic lumbar spinal instability were selected from the Ninth and Second People's Hospital from March 2003 to March 2007. They received dorsal spinal strenosis surgical decompression, titanium JJXA segmental pedicle screw fixation, intervertebral pace brace, intervertebral disc resection, with the sideward and the forward annulus fibrosus retained, endplate cartilage zone curetted, then received intervertebral bone particles graft, and pedicle screw compression. The patients were followed up for more than 15 months. The good and excellent rate was 91.3%.

选择2003-03/2007-03南阳市第九人民医院和南阳市第二人民医院收治的动力性腰椎不稳患者46例,行后正中入路下的椎管减压手术,钛制JJXA椎弓根螺钉置入,并行椎间隙撑开,双侧切除椎间盘保留侧方以及前方的纤维环,刮除终板的软骨层,行椎间颗粒骨植骨,椎弓根螺钉系统加压固定。46例随访时间≥15个月,优良率91.3%。

Plating might not be the optimal solution for comminuted C3 fractures with a thin articular shell and small juxta-articular fragments.

对于带有薄薄的外壳骨和小关节旁软骨碎片的粉碎性C3骨折钢板接骨术并不一定是最佳的选择方案。

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然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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