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Presurgical nasal molding produced tissue expansion of the short columella and corrected the nasal tip cartilages. Up to 5 months of active treatment was needed before lip repair.

将前颌骨向后移动,排列在两侧牙槽骨之间,使牙槽骨成为较为规则的弧形排列;鼻软骨塑形及鼻小柱延长。

Results: Compared test group with control group at 14th day of experiment, test group rats were osteoporotic. The lower bone density figures of test group showed that bones were osteoporotic and test group bone HE microtome section showed that bone trabecula was looser, os integumentale was thiner and chondrocyte was decreased.

结果:实验第14天,模型组与对照组相比,模型组大鼠骨质疏松模型建立成功:骨密度不同程度的降低、骨HE切片中骨小梁稀松、皮质骨变薄、软骨细胞层减少等病理变化。

Results Early signs of ANFH using CT showed that, in 26 femoral heads in 21 cases, there were radiate star shape of high-density osteosclerosis of the trabeculae in 8 femoral head.

结果 CT早期表现:2 1例 2 6个股骨头,其中 8个股骨头骨小梁呈放射状密度增高的"星状征",骨小梁境界清楚、锐利属Ⅰ期;18个股骨头表现为骨硬化,骨小梁结构消失、模糊不清,骨密度减低及囊性改变,属Ⅱ期;并有 3个股头在Ⅱ期影像改变基础上出现软骨下骨折及轻微塌陷,属Ⅲ期。

MRI of 36 cases with acute cartilage injury of knee confirmed by arthroscopy and arthrostomy were retrospectively analyzed, with emphasis on articular cartilage and subchondral lesion.

分析其中36例经关节镜或手术证实关节软骨损伤患者的膝关节MRI所见,着重观察关节软骨和软骨下骨的改变,并与关节镜和手术结果对照分析。

Mri of 36 cases with acute cartilage injury of knee confirmed by arthroscopy and arthrostomy were retrospectively analyzed, with emphasis on articular cartilage and subchondral lesion.

分析其中36例经关节镜或手术证实为关节软骨损伤患者的膝关节mri所见,着重观察关节软骨和软骨下骨的改变,并与关节镜和手术结果对照分析。

Mallory trichrism staining exhibited light blue samples. Eight weeks following repair, CT showed round blunt defect edges in the coronal position, which had bony pustute connection with gel materials. Density at the defect region significantly increased. 3D reconstruction suggested that defects became small. After hematoxylin-eosin staining, abundant fibrous connective tissue appeared in defect regions, with bony tissues. Mallory trichrism staining revealed that maroon mature bone tissues were found, surrounded by light blue chondroid tissues. Twelve weeks following repair, coronal defect regions were filled with callus. 3D reconstruction showed that defects were repaired. Defect region and surrounding bony tissues had bony connection, with thick bone trabecula and mature Haversian system.

修复后8周,冠状位CT显示缺损边缘圆钝,与凝胶材料有骨性突起连接,缺损处密度增高明显,三维重建显示缺损范围较之前有所减小;标本苏木精-伊红染色后缺损部可见大量含血管成分的纤维结缔组织,有骨样组织结构形成,Mallory三色染色显示有褐红色成熟骨组织形成,其旁边有淡蓝色软骨样组织修复后12周,冠状位CT显示缺损区基本被骨痂填满,三维重建示缺损基本修复;缺损区域和周围骨组织形成骨性结合,骨小梁粗大,哈弗氏系统成熟。

CT displayed the structure of femoral head was vague. A piece of coloboma could be observed clearly on the cartilage of a femoral head. Medullary canal was almost filled with white adipose tissue. Osteoblasts and osteocytes decreased. Empty bone lacuna increased. Thrombus distributed widely in the bone tissue microcirculation.

MA组病理检查肉眼可见股骨头软骨面局部缺损,坏死面暴露,髓腔内大量脂肪组织堆积;光镜下成骨细胞、骨细胞均减少,空骨陷窝增多,微小血栓广泛分布,变形扩大的脂肪细胞挤压正常骨髓组织细胞,骨小梁变细破裂明显。

Results Intramuscularly injected with hydrochloric dexamethasone for6weeks,the rabbits in osteoporosis model group showed obvious signs of osseous destruction such as destruction in the facies articularis of femur head,rar-efaction and fragmentation of trabecula,disappearance of myeloid cells,while those in control groop showed few sign of osseous destruction.

结果 对实验兔予以肌肉注射DX6周后,正常对照组基本无骨质破坏的征象,而骨质疏松模型组则表现为股骨头关节表面软骨破坏,骨小梁稀疏、断裂,骨母细胞消失等明显骨破坏现象。

RESULTS: During 10 - 12 weeks, in cuntrol group: The defect area was repaired by white and soft tissue that had no resistance to press. The repaired tissue was still lower than the surrounding articular surface with clear boundary. By histological observation, it was found that the defect was repaired by the mechanism similar to inflammatory reaction and the defect is ultimately filled by the hyperplasia of hyaline degenerative fibrous tissues. In filling group: the defect was repaired by semi-transparent, smooth, textured tissues with polish that had resistance to press as well as elasticity. The repaired tissue was almost similar to the shape of the surrounding cartilage,difficult to be distinguished. After histological observation, it was found that there was no inflammatory reaction, but active hyperplasia of inner bonetissue and cartilage tissues; a lot of osteoid tissues and trabeculation were found. Newlborn cartilage was fused with surrounding cartilage tissue and connected with surrounding tissues.

结果:10~12周,对照组:缺损区由白色、质软、按压无阻抗的组织修复,修复组织仍低于周围关节面,边界仍清晰可辨,组织学以类似炎症反应的机制修复缺损,最终以透明变性的纤维组织的增生来填补缺损部位;填充组:缺损区由半透明状、质韧光滑有光泽,按压有阻抗并有弹性的组织修复,修复组织与周围软骨外形上已基本相似,不易区分,组织学未见有炎症反应的过程,内骨组织和软骨组织增生活跃,并可见大量类骨组织和骨小梁形成,新生软骨和周围软骨组织融合,并与周围组织连接。

Results Histological investigation showed that the bone trabeculae were disarrayed containing dispersed cartilage cells in the denervated side, whereas the bone trabeculae disarryed orderly with rich blood vessels and no cartilage cell in the control side.

结果 实验侧牵张间隙骨小梁分布方向较杂乱,骨小梁内部有分散的软骨岛分布;对照侧牵张间隙骨小梁主要沿牵张方向分布,血管丰富,成骨细胞活跃。

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