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Objective To investigate the expression of type Ⅱ collagen in the articular chondrocyte of osteoarthritis patients and normal human.

目的 通过观察Ⅱ型胶原mRNA在骨关节炎(osteoarthritis,OA)患者关节软骨细胞与正常关节软骨细胞中的表达情况,探讨Ⅱ型胶原在骨关节炎中的作用。

The malignant tumors included osteogenic osteosarcoma,metastasis tumor(six patients,two with pathologic fractures),chondrosarcoma,malignant fibrous histiocytoma (three patients,one with pathologic fracture),fibrosarcoma,and solitary myeloma.all patients received limb savage procedure with custom knee prosthesis including sevnteen cases of hinge joint and twentyone cases of posterior stability joints.

回顾分析我院接受定制型人工关节置换进行保肢治疗的股骨远端肿瘤患者38 例,其中良性肿瘤9 例,分别是骨巨细胞瘤7例(复发性骨巨细胞瘤5 例,骨折2例),骨巨细胞瘤合并动脉瘤样骨囊肿1 例,骨母细胞瘤1 例;恶性肿瘤29 例,分别是成骨性骨肉瘤16 例,转移性肿瘤6例(骨折2例),软骨肉瘤2 例,恶性纤维组织细胞瘤3例(骨折1例),纤维肉瘤1 例,局灶性骨髓瘤1 例。

At 12 week, the cartilage surface of the MSCs/ HA/CPP/PLLA group was smooth, cartilage layer with normal thickness and complete subcartilaginous bone were observed with light microscope, which had significant differences compared with the control group.

细胞材料复合物组12周关节软骨表面光滑,光镜下可见已形成正常软骨厚度的软骨层及完整的软骨下骨,与对照组有明显差异。

Osteoarthritisis a non-specific inflammation which is mainly characterized by the changes in the cartilage; it could result in subchondral bone necrosis,cystis degeneration,bone mineral densityincrease and the osteophyte formation.

骨关节炎是以软骨改变为主要特征,进而造成软骨下骨坏死、囊性变、骨密度增加和伴发骨赘形成的一种非特异性炎症。

Objective To explore the role of epiphyseal plate and cartilage whether or not to resist the invasion of osteosarcoma.tumor stage of invasion.mode of invasion and mechanism of genesis.

摘 要:目的探讨骨骺软骨板和关节软骨有无抵抗骨肉瘤侵犯的作用。

Results: Gd-enhanced MRI enabled to make differentiation between physeal and epiphyseal cartilage and reveal epiphyseal vascular canals.

结果:Gd增强MR成像能够区别骨骺软骨和生长板软骨,能够显示骨骺内的血管槽。

It starts transmitting information by integrating with lagen and stromatin by irritating osteocytes and chondrocytes to form rapidly extracellular matrix so as to promote repair of bone and cartilage injury.

转化生长因子β通过刺激骨、软骨细胞合成胶原和基质蛋白,快速形成细胞外基质,达到其促进骨、软骨损伤修复的作用。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞,使这些细胞活化,产生金属蛋白酶、胶原酶、基膜溶解酶等,导致局部炎症反应和血管翳形成,进一步引起软骨破坏和骨侵蚀。

Then 3 rabbits with 6 limbs of each group were killed in the 1st, 3, 5, 7, 10 and 13th week respectively, to compare the bone healing roentgenologically and histologically There was receptive reaction in fresh homogenous bone implant ati...

实验证明脱钙同种异体骨是一种较好的植入物。彼优于新鲜异体骨,与新鲜自体骨植入无显著差异。新骨及软骨出现在植入物中而不在邻近宿主骨处,表明新骨形成可能是骨诱导作用的结果。

Furthermore, the connection between two sesamoids and metacarpal was a kind of soft tissue connection which seemed like fabric, it could exist mini-motion between two sesamoids and metacarpal, resulting in the increasing friction between the tendon of flexor pollicis longus muscle and sesamoids. Meantime, it could lead to metacarpophalangeal joints dislocation and injury the tendon sheath of flexor pollicis longus muscle.

而且,籽骨和掌骨之间没有骨性连接,为纤维软骨样软组织连接,导致籽骨和掌骨之间可以微动,拇指屈伸时,籽骨和掌骨间的微动导致拇长屈肌腱与籽骨摩擦进一步加大,籽骨易脱位,产生籽骨嵌顿于掌指关节,造成拇长屈肌腱狭窄性腱鞘损伤。

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