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The histopathological findings of the partial ADD included the loss of chon- drocyte, horizontal splitting of the condylar cartilage and synovitis at early stage, and the hyperplasia of chondrocyte, the disarrangement of collagen fibers at late stage, but the articular surface remained intact.

完全性关节盘前移位和关节盘穿孔的组织病理研究发现,髁状突软骨变薄,部分区域软骨丧失,软骨细胞增生成族,肉芽组织形成,软骨及软骨下骨出现水平及垂直裂隙,软骨下骨纤维形成,甚至出现囊肿。

EMA was the most effective antibody for differentiating chordoid meningioma from skeletal myxoid chondrosarcoma, low-grade chondrosarcoma, and enchondroma, whereas D2-40 was the most effective antibody for differentiating chordoid meningioma from extraskeletal myxoid chondrosarcoma and chordoma.

EMA是鉴别脊索样脑膜瘤和骨的黏液样软骨肉瘤、低级别软骨肉瘤、内生性软骨瘤最有效的抗体,而D2-40则是鉴别脊索样脑膜瘤和骨外黏液样软骨肉瘤、脊索瘤最有效的抗体。

At early stage after brain injury, there were a quantity of fibrous callus and cartilaginous callus formation in brain injury and fracture group and many neuropeptides immunoreactive nerve fibers in callus were found. Strong immunoreactivites of CGRP, SP, VIP, NPY, TOH occurred to osteogenitor cells and chondroblast, which proliferated in thickened endothecium.

脑损伤合并骨折组早期形成大量纤维骨痂和软骨骨痂,骨痂中神经肽免疫阳性神经纤维较多,明显增厚的骨膜内层骨祖细胞、幼稚的软骨细胞胞质内降钙素基因相关肽、P物质、血管活性肠肽、酪氨酸羟化酶、神经肽Y强阳性表达。

During the process of osteophyte formation mesenchymal cells covering the periosteal bone surface proliferate and differentiate into chondroblasts and osteoblasts, which build up cartilage and bone matrix.

在骨赘形成过程中,覆盖骨膜骨的间充质细胞增生、分化为软骨母细胞和成骨细胞,后两者构建了软骨和骨基质。

After 24 weeks,the operation area of group A was more smooth,and the surrounding normal cartilage naturally straight flush,transparent form new cartilage,subchondral bone formation in good condition;Group B restoration surgery the basic integrity of the cartilage tissue, center is not yet fully integrated,there was slight depression;CollagenⅡimmunohistochemistry of cartilage that was new brown area.Group C has no formation of articular cartilage.The growth and the intergration of subchondral bone of group A and B were better.

术后24周取材,见A组山羊手术区关节表面较为光滑,与周边正常软骨自然连续平齐,透明的新生软骨组织形成,软骨下骨形成完好;B组山羊手术区修复的软骨组织基本完整,中心部位仍未完全融合,有微小凹陷;Ⅱ型胶原免疫组化示新生软骨组织呈棕黄色。C组术区关节凹陷,无关节软骨组织形成。A组和B组,软骨下骨的生长及与周围组织的结合均较好,无植入物脱落现象的发生。

In this study, immunohistochemical staining was performed with antibodies against D2-40, S100, pankeratin, epithelial membrane antigen, brachyury, and glial fibrillary acidic protein in 4 cases of chordoid glioma, 6 skeletal myxoid chondrosarcomas, 10 chordoid meningiomas, 16 extraskeletal myxoid chondrosarcoma, 18 chordomas, 22 low-grade chondrosarcomas, and 27 enchondromas.

本研究中,我们给4例脊索样胶质瘤、6例骨的黏液样软骨肉瘤、10脊索样脑膜瘤、16例骨外黏液样软骨肉瘤、18例脊索瘤、22例低级别软骨肉瘤和27例内生性软骨瘤做了D2-40、S100、pankeratin、上皮膜抗原、brachyury和胶质纤维酸性蛋白的免疫组化染色。

Results (1) Primary callus came into being 3 days after operation. Mesenchymal cells from peripheral tissues around the primary callus were differentiated into chondrocytes 1 week later. Endochondral ossification was going on then. Bridging callus was formed in the fracture sites 4 weeks after operation.

结果 (1)伤后3 d开始形成原始骨痂。1周时肉芽组织中的间质细胞开始分化为软骨细胞,软骨形成后再进行软骨内化骨。4周时形成连接骨折端的桥接骨痂。

In the MRI group, MR images were taken and assessed for location and severity of defects of cartilage by Noyes classification, osteophytes, subchondral cysts, sclerosis, meniscal and/or ligamentous tears.

MRI组根据MRI影像诊断软骨缺损的部位,对软骨缺损严重程度进行Noyes分级,对韧带、半月板、骨赘和软骨下骨囊腔改变情况进行评定,并诊断是否属于前内侧骨关节病变。

Results Extensive and diffuse synovial hyperplasia can be seen in patients with RA;synovial pannus formation can be seen in 25 cases.

结果RA组病人均可见广泛、弥漫的滑膜增生,其中25例病人可见滑膜血管翳形成,而OA组仅7例病人可见轻度滑膜增厚,未见滑膜血管翳形成者(X2=55.78P.005);RA组关节软骨及软骨下骨改变较严重且弥漫,而OA组软骨退变则较局限,且以关节摩擦大的部位受损为著,其软骨下骨改变较为局限,常常见于IV软骨退变;关节腔积液、半月板及韧带改变,在OA组与RA组之间无差异。

Methods Fifty healthy SD rats were fed for twentytwo months in order to build the model of aging rats, the histology of femoral bone, tibial bone and lumbal vertebra was used to observe, then we evaluated the indexes which reflect the degeneration of intervertebral disc including the quantity of collagen type Ⅱ,Ⅹ of intervertebral disc by the immunohistochemistry methods, the relative area of vascular bud, the thickness of calcified layer and uncalcified layer on cartilage endplate and the indexes which reflect the osteoporosis including the thickness ratio of cortical bone, the relative area of bone trabecula, the bone density, the max stress and straining of bone.

50只健康纯种SD大鼠,喂养22个月,建立老龄大鼠模型,进行股骨、胫骨、腰椎等组织学观察,并评价椎间盘退变的相关指标(椎间盘软骨Ⅱ型和Ⅹ型胶原表达、软骨终板血管芽相对面积、软骨终板钙化层/非钙化层厚度)与骨质疏松的相关指标(骨皮质厚度指数、骨小梁相对面积、骨密度、骨最大应力和应变)的相关性。

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