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The purpose of this paper is to discuss the degree that different swimming exercise affect the bone mass and bone biochemical marker of rats that was in the growth period, to investigate its possible mechanisams, to further enrich the theory that physical activity can promote the healthy of bone.

本研究的目的是:通过动物实验探讨不同强度的游泳运动对生长期大鼠骨量积累的作用效果及对骨代谢生化指标的影响,并探讨其可能的作用机理,进一步丰富体育运动促进骨健康的理论;同时为青少年选择合理的促进骨骼生长、获得较高的基础骨量、预防骨质疏松症运动处方提供一定实验理论依据。

To some degree, this study revealed the relationship between ossein and bone miner and the important preventive and therapeutic effects of ossein on OP. It provides theoretical and experimental basis for the research and development of effective prescriptions to cure OP. Limited by the actual experimental situation, we only did some study on the synthesis and content of type Ⅰ collagen. Further study on the changes of decomposition and structure of type Ⅰ collagen are needed to be done.

本课题的研究,在一定程度上揭示了骨胶原纤维和矿物质之间互根互用的辨证关系,及Ⅰ型胶原在骨质疏松症的发病和治疗中所起的重要作用,并为开发研制治疗本病的有效中药复方提供了理论和实验依据,但由于条件所限,本研究仅就Ⅰ型胶原的合成及其含量变化做了初步观察,而本病中骨胶原纤维的分解代谢及其结构的改变,尚待进一步探讨。

Result:As compared with the model group, the effect of small dose group and middle dose group of osteopractic total flavone on TBV% of shankbone increased significantly; the effect of small dose group and middle dose group of osteopractic total flavone on TRS% of shankbone reduced significantly and TFS%, AFS%, MAR, BFR of shankbone reduced obviously; the effect of middle dose group of osteopractic total flavone on OSW and mAR reduced obviously, the effect of small dose group of osteopractic total flavone on them had the tendency of reducing, but there was no statistical significance.

结果 :对胫骨骨小梁体积百分比的影响,与模型组比较,骨碎补总黄酮小剂量组和中剂量组的TBV %明显增高;对胫骨骨小梁吸收表面百分比的影响,与模型组比较,骨碎补总黄酮小剂量组、中剂量组的TRS %显著降低;对胫骨骨小梁形成表面百分比,活性生成表面百分比,骨小梁矿化率和骨小梁骨生成率的影响,骨碎补总黄酮小剂量组、中剂量组的TFS %,AFS %,MAR ,BFR较模型组皆明显降低;对胫骨类骨质平均宽度和骨皮质矿化率的影响,骨碎补总黄酮中剂量组的OSW和mAR与模型组比较,明显降低;骨碎补总黄酮小剂量组与之相比,有下降的趋势,但无统计学意义。

According to our results, since BaP increased the expression of COX2 and pp38 to reduce the osteoblast differentiation and this phenomenon can reverse by treatment of NS398, but not by treatment of SB203580, suggesting that COX2 activation plays an important role on osteoblast differentiation. Adlay could increase osteoblast differentiation, in co-culture system, and reverse the osteoporotic status in mice, would be a helpful healthy food for enhance osteoblast differentiation. However, about, TBT, we didn't have enough data to support its effect on the differentiation of osteoblast or osteoclast.

所以依据我们所做出的实验结果,虽然苯骈芘会增加COX2和pp38的蛋白表现,但造骨细胞的分化作用仍下降,但若同时添加NS398,则分化能力有恢复现象,这或许可推测说COX2活性在抑制造骨细胞分化上扮演了一个重要角色;薏苡仁在共同细胞培养可以增加造骨细胞的分化作用,且对骨质疏松状态的小鼠具有缓解的能力,因此或许是能促进造骨细胞分化的营养食品;至於三丁基锡由於实验的数据不多,推测其或许并不影响造骨细胞和破骨细胞的分化作用。

Objective To analyze the CT and MRI manifestations of oral carcinoma,and to evaluate the value of imaging technologies in the diagnosis of oral carcinoma,thus to explore the most reasonable imaging method Methods 46 cases with oral carcinoma,proved by surgery and pathology (2 lip tumors,8 carcinomas of the gingival ridge,5 carcinomas of the buccal mucosa,24 tongue carcinomas,5 carcinomas of the floor of the mouth,2 tumors of the hard palate),were analysed retrospectively32 cases were examined with CT and 14 cases with MRIImaging presentations were compared with surgery and pathology Results Of the 46 cases with oral carcinoma,22 were ulcerative lesion of infiltrative growth,24 were masslike lesion of extruded trowthOf the 32 cases examined with CT scan,27 were detected,5 were missed,the 4 missed cases were confirmed to be superficial ulcers by surgery and pathologyOf the 10 cases with bone destruction examined with CT scan,8 were manifested,2 were missedAnd of the 14 cases with MRI scan,all 14 were detected Conclusion CT and MRI scan are valuable for diagnosis of oral carcinomasThey can manifest the morphology and size of primary tumor,contiguous structures,bone invasion and cervical lymph node metastasisMRI is the optimal imaging method for superficial ulcerative lesion of infiltratibe growth

徐 锋,罗德红,唐威,欧阳汉,周纯武目的分析口腔癌的CT及MRI表现,评价影像检查在口腔癌诊断中的应用价值,探索合理的影像学检查方法。方法回顾性分析经手术及病理证实的口腔癌46例(唇癌2例,牙龈癌8例,颊黏膜癌5例,舌癌24例,口底癌5例,硬腭癌2例),其中32例行CT扫描,14例行MRI扫描,将影像表现与手术所见及病理结果进行对照分析。结果 46例口腔癌中,呈浸润性生长的溃疡型病变22例,外生性生长的肿物型病变24例。CT扫描32例,明确显示病变27例,遗漏病变5例,其中4例为表浅溃疡型病变。CT扫描病例中,10例有骨质侵犯,CT扫描准确评价8例,遗漏2例。MRI扫描14例,均准确评价肿瘤及其与周围结构的关系。结论 CT、MRI对口腔癌原发肿瘤的形态、大小、周围结构侵犯、颈部淋巴结转移的评价有重要价值。对于较小及呈浸润性生长的表浅溃疡型肿瘤,CT扫描尤其是CT平扫难以准确显示,应首选MRI。

Objective To analyze the CT and MRI manifestations of oral carcinoma,and to evaluate the value of imaging technologies in the diagnosis of oral carcinoma,thus to explore the most reasonable imaging method Methods 46 cases with oral carcinoma,proved by surgery and pathology (2 lip tumors,8 carcinomas of the gingival ridge,5 carcinomas of the buccal mucosa,24 tongue carcinomas,5 carcinomas of the floor of the mouth,2 tumors of the hard palate),were analysed retrospectively32 cases were examined with CT and 14 cases with MRIImaging presentations were compared with surgery and pathology Results Of the 46 cases with oral carcinoma,22 were ulcerative lesion of infiltrative growth,24 were masslike lesion of extruded trowthOf the 32 cases examined with CT scan,27 were detected,5 were missed,the 4 missed cases were confirmed to be superficial ulcers by surgery and pathologyOf the 10 cases with bone destruction examined with CT scan,8 were manifested,2 were missedAnd of the 14 cases with MRI scan,all 14 were detected Conclusion CT and MRI scan are valuable for diagnosis of oral carcinomasThey can manifest the morphology and size of primary tumor,contiguous structures,bone invasion and cervical lymph node metastasisMRI is the optimal imaging method for superficial ulcerative lesion of infiltratibe growth

中华硕博网核心提示:徐锋,罗德红,唐威,欧阳汉,周纯武关键词:口腔肿瘤目的分析口腔癌的CT及MRI表现,评价影像检查在口腔癌诊断中的应用价值,探徐锋,罗德红,唐威,欧阳汉,周纯武目的分析口腔癌的CT及MRI表现,评价影像检查在口腔癌诊断中的应用价值,探索合理的影像学检查方法。方法回顾性分析经手术及病理证实的口腔癌46例(唇癌2例,牙龈癌8例,颊黏膜癌5例,舌癌24例,口底癌5例,硬腭癌2例),其中32例行CT扫描,14例行MRI扫描,将影像表现与手术所见及病理结果进行对照分析。结果46例口腔癌中,呈浸润性生长的溃疡型病变22例,外生性生长的肿物型病变24例。CT扫描32例,明确显示病变27例,遗漏病变5例,其中4例为表浅溃疡型病变。CT扫描病例中,10例有骨质侵犯,CT扫描准确评价8例,遗漏2例。MRI扫描14例,均准确评价肿瘤及其与四周结构的关系。结论 CT、MRI对口腔癌原发肿瘤的形态、大小、四周结构侵犯、颈部淋巴结转移的评价有重要价值。对于较小及呈浸润性生长的表浅溃疡型肿瘤,CT扫描尤其是CT平扫难以准确显示,应首选MRI。

Octacosanol through the molecular distillation technology and high-vacuum separation technology at bee wax and rice bran extract, octacosanol the treatment of excessive calcium osteoporosis, treatment of high cholesterol and high LDL blood type as well as to promote blood and activation of cell cycle, and enhance endurance, energy and stamina, and many other physiological functions; taurine are the first in 1827 at the Ox bile found in a special amino acid, commonly found in natural biology of the human body in vivo an essential nutritional elements, known as "the fulcrum of the body's health balance."

二十八烷醇是通过分子蒸馏技术和高真空分离技术在蜂腊和米糠中提取,二十八烷醇对治疗血钙过多的骨质疏松,治疗高胆固醇和高脂蛋白血型以及促进血液循环和活化细胞,增强耐力、精力和体力等众多的生理功能;牛磺酸是1827年首先在牛的胆汁中发现的一种特殊氨基酸,普遍存在于自然界的生物体内人体内一种必不可少的营养元素,被誉为&人体平衡的健康支点&。

The recommended leel of serum itamin D is the leel at which the parathyroid leel does not become hyperactie, but we now know that itamin D affects not only the parathyroid gland, but all these other systems in the body, and it appears we need een higher leels to hae a positie effect on these other systems, he said.

骨质疏松症的妇女维生素D推荐摄入量为1200单位/天。&他解释到,&这个标准的制定是在无甲状旁腺功能亢进时的维生素D水平。但是进一步的研究结果显示高剂量的维生素D对于全身的其他器官有着积极的作用。

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