骨质疏松的

In vitro experiment results demonstrated that the decrease in reproductive activity in vitro of BMSCs of osteoporosis rats contributes to osteoporotic cytopathology.

体外实验结果表明，骨质疏松大鼠骨髓间充质干细胞的体外增殖能力下降可能是骨质疏松的细胞病理学机制。

OBJECTIVE: BMSCs from osteoporosis rats were isolated and cultured in vitro. To observe biological features of BMSCs of rat models of osteoporosis, to analyze cytopathology mechanism of osteoporosis, and to provide a significant drug target for prevention and treatment of osteoporosis.

目的：对骨质疏松大鼠骨髓间充质干细胞进行分离和体外培养，观察骨质疏松模型大鼠骨髓间充质干细胞的生物学特性，分析骨质疏松的细胞病理学机制，以期为骨质疏松的防治提供一个有意义的药物靶标。

The mechanical strain induces the up-regulation of expression of integrin α2、β1、β3 on the membrane of osteoblasts from 3control group and promoted prolifration and differentiation of osteoblasts from 3control group at 400μstrain. The expression of integrin α2、β1、β3 and Doctorship Thesis of Sichuan University------Abstractsynthesize function of bone matrix in osteobla

上述实验结果提示：16月龄大鼠复制成年人雌激素缺失骨质疏松的模型优于3月龄大鼠骨质疏松模型。2力学刺激可引起正常大鼠和骨质疏大鼠成骨细胞膜表面integrinα2、β1、β3表达

Exercise has slight influence on bone formation biochemical.

关于骨质疏松的机制至今尚未完全清楚，但运动作为影响骨质疏松的因素已为学术界所重视。

According to experimental results and etiopathogenisis and pathology of osteoporosis , and analyzing review investigation on hepcidin、associations of bone metabolism and iron metabolism and relations of ferri ion and calcium ion,we can make conclusions as follows: 1、We applied single manmade intervention approach to induce osteoporosis model in this study, there was no other influential factor. In the termination of test , rats bone density and bone histological anatomy indicated that osteoporosis model was creditable,meanwhile hepatic functional enzyme and hepatic microtome section demonstrated that hepatic function had noci-influence induced by medicinal herbs resource. Accordingly, we could believe that hepatic hepcidin gene expression and serum hepcidin contents can represent internal iron metabolism changes at selected test time. 2、In this investigation, different findings between test group and control group indicated that:according to changes of hepcidin gene expression measured by RT-PCR and changes of serum hepcidin contents determined by ELISA kit , there were correlations between hepcidin and rat osteoporosis model induced by retinoic acid. 3、Under the condition of this investigation,there was a interactive hypothesis as follows: Hepcidin iron metabolism←→ferriion←→calcium ion←→osteoporosis.

根据本次实验结果，对骨质疏松的病因病理的认识及铁代谢与铁调素、骨代谢与铁代谢关系、铁离子与钙离子的关系系列研究的回顾，经分析得出如下结论：1、本研究骨质疏松模型采用单一人工干预方法，没有其他影响因素；实验结束时大鼠骨密度、骨组织学检查表明骨质疏松形成，同时肝脏功能酶和HE切片显示肝脏功能未受药源性产生明显损伤性影响；因此，同期不同时间组大鼠肝脏铁调素基因表达、血清铁调素含量可以代表体内铁代谢不同时间的变化。2、在本研究中，模型组与对照组研究结果的差异表明：铁调素基因RT-PCR变化、血清铁调素ELISA测定含量变化与维甲酸制作的大鼠骨质疏松模型形成有实验相关性。3、在本研究平台下，形成了一个互相影响的假设图：铁调素←→铁代谢←→铁离子←→钙离子骨质疏松。

Objective: To study the relationship between type 2 diabetes and the occurrence of osteoporosis.

目的：探讨2型糖尿病与骨质疏松的关系，为糖尿病并发骨质疏松的机理研究提供基础资料。

If women reduce the times of parturition in young, they might reduce the incidence of osteoporosis after middle aged.

骨质疏松受多种因素的影响，年轻时控制产次，可能减少中老年后骨质疏松的发生。

this research put forward a new idea and method on the treatment of the rarefaction of bone due to diabetes, and also provide a scientific basis for the treatment of the disease with Tanggukang Capsule and it may has good prospects.

该课题提出了治疗糖尿病骨质疏松的新思路及方法，为临床治疗该病开拓了新的途径，为糖骨康胶囊治疗糖尿病骨质疏松提供科学依据，可能具有前瞻性临床价值。

Clinical study indicated: the flavone of rhizome drynaria can promote collagen synthesis, improve bone transition, increase bone formation, delay bone resorption, furthermore, improve SOP patients' integer bone mass and proximate of femur bone strength, and prevent fracture of hip.Eventually, the level of living independence amended and the quality of life improved overall.

临床研究表明：骨碎补总黄酮具有促进老年性骨质疏松症骨胶原的合成，提高骨转换，增加骨形成，减缓骨吸收状况等作用，进而提高老年性骨质疏松的整体骨量，缓解腰背痛，提高股骨近端骨强度，预防髋部骨折，提升独立性生活水准，全面提高老年性骨质疏松症患者的生命质量。

Chances are that a loose-hipped dog that mates with another loose-hipped dog will give birth to a dysplastic puppy.

当一只髋骨骨质疏松的狗和另一只骨质疏松的狗配对，生下的小狗会造成异型增生现象。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。