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骨肿瘤

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The malignant tumors included osteogenic osteosarcoma,metastasis tumor(six patients,two with pathologic fractures),chondrosarcoma,malignant fibrous histiocytoma (three patients,one with pathologic fracture),fibrosarcoma,and solitary myeloma.all patients received limb savage procedure with custom knee prosthesis including sevnteen cases of hinge joint and twentyone cases of posterior stability joints.

回顾分析我院接受定制型人工关节置换进行保肢治疗的股骨远端肿瘤患者38 例,其中良性肿瘤9 例,分别是骨巨细胞瘤7例(复发性骨巨细胞瘤5 例,骨折2例),骨巨细胞瘤合并动脉瘤样骨囊肿1 例,骨母细胞瘤1 例;恶性肿瘤29 例,分别是成骨性骨肉瘤16 例,转移性肿瘤6例(骨折2例),软骨肉瘤2 例,恶性纤维组织细胞瘤3例(骨折1例),纤维肉瘤1 例,局灶性骨髓瘤1 例。

The fundamental imaging features of osteosarcoma were showed bone destruction, periosteal reaction, neoplastic bone and soft-tissue mass. Among 49 cases examined by radiography, osteoblastic pattern sarcoma was found in 19 cases, osteolytic pattern sarcoma was found in 13 cases and mixed pattern sarcoma was found in 17 cases. The detection rates of bone destruction, periosteal reaction, soft-tissue mass, neoplastic bone and Codman triangle by radiography were respectively 61.2%, 95.9%, 71.4%, 73.5%and 27.7%. All 10 cases with CT scan were showed bone destruction, soft - tissue mass and neoplastic bone. The detection rates of periosteal reaction,憇ieve sign挶 and Codman triangle with CT scan were respectively 90%, 90% and 11%. The tiny neoplastic bone and"sieve sign"were showed sensitively by CT, but Codman triangle was showed by radiography superior to CT.32 cases with MRI scan presented the normal marrow was replaced by the tumor, which was showed low to intermediate signal intensity on T1-weighted images and promiscuity signal intensity on T2-weighted images. 7 cases presented hemorrhage and 24 cases presented necrosis.

骨肉瘤基本影像表现为骨质破坏、骨膜反应、瘤骨和软组织肿块。49例X线表现为成骨型19例,溶骨型13例,混合型17例;X线对骨质破坏、骨膜反应、软组织肿块、瘤骨和Codman三角的检出率分别为61.2%、95.9%、71.4%、73.5%和27.7%;10例CT表现均可见骨质破坏、软组织肿块及瘤骨,CT对骨膜反应、筛孔征和Codman三角的检出率为90%、90%和11%;CT对显示细小肿瘤骨和筛孔征最敏感,但对Codman三角的显示不如X线平片;32例MRI表现为骨髓腔内正常的骨髓高信号被肿瘤信号所取代,T1WI呈低~等信号,T2WI呈混杂信号,7例合并出血,24例中央坏死囊变,32例增强扫描均呈不均匀强化及瘤周可见水肿区。

Cases of parosteal osteosarcoma on tibia showed bony tumor, which basilar part accreted surface of bone on X-ray, and vicinity cortical bone hyperplasia and harden, soft tissue mass with focal or cauliflower-like high density tumor bone in it. A lucent zone between the cortex and tumor bone was noticed in 1 case.

发生在胫骨的3例病例中X线表现为基底部附着于骨表面的骨性肿块,邻近骨皮质增生硬化,软组织内可见团状和菜花状不规则高密度瘤骨,其中1例与骨皮质关系密切病例可见到骨皮质与肿瘤骨之间有一透亮带。

OC, BSP, OPN all showed low expression in unmineralized neoplastic bone matrix In mineralized neoplastic bone matrix, BSP and OPN showed high expression and OC showed low expression.

三者在未矿化肿瘤骨基质中均呈低表达,在矿化肿瘤骨基质中BSP、OPN呈高表达,OC呈低表达,在正常成熟骨中,三者均呈高表达。

Objective To study the clinical application of microwave in treatment of malignant tumors around knee joints with the purpose of killing the tumor cells in situ and reserving the ligaments and meniscus for limb salˉvage.

目的 探讨在保留膝关节韧带和半月板的条件下利用微波对膝关节周围恶性骨肿瘤进行原位热疗保肢治疗的临床效果及价值。

Using this algorithm, osteomas can be effectively classified by the fractal parameters as expected.

利用该算法,可根据分形参数模式集对骨肿瘤进行有效的分类,达到了预期的目标。

For most people, the first symptom of primary bone cancer is pain.

对大多数人来说,首发症状的原发性骨肿瘤是疼痛。

Methods: Clinical and CT data of 28 cases of neoplastic lesions of jawbones proved pathologically and surgically were investigated retrospectively. The characteristic manifestations of CT were analyzed.

回顾性研究28例经手术和病理证实的颌骨肿瘤的临床及CT资料,分析各种病变的影像特点。

The giant cell tumor of spine has its own specific radiographic feature. There is some recurrence in simple curettage of tumor lesion. The thoroughly en bloc resection of tumor or spondylectomy, bone fusion and strong inter fixation are the key points for successful surgical treatment, the clinic behavior of bone giant cell tumor is somewhat unpredictable.

脊柱骨巨细胞瘤之影像学表现有其特殊性;肿瘤彻底切除、植骨融合及坚强的内固定是手术成功的关键,单纯肿瘤病灶切除术存在一定的复发率;骨巨细胞瘤的临床行为具有一定的不可测性。

Objective: To summarize and evaluate the efficiency of treatment of limb malignant bone tumors with cryosurgery.

目的:总结和评估液氮冷冻治疗肢体恶性骨肿瘤的价值。

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