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骨肿瘤

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Objective To observe the different features, rate of occurrence, diffusing parts of cancers of various organs through bone diffusing with nuclein bone scanning of lung cancer, breast cancer, prostate cancer and nasopharyngeal carcinoma.

目的对肺癌、乳腺癌、前列腺癌、鼻咽癌进行放射性核素骨显像,以观察不同脏器肿瘤骨转移的特点、发生率及转移部位。

Among 14 cases of trigeminal tumor,12 cases were examined by CT scanning,2 cases by MRI,all of them were confirmed by pathological examination.The density appeared heterogeneous with 6 cases,homogeneous high density with 5 cases and isopyknic with 1 case.Dropped contrast medium,the 12 CT scanning pictures appeared heterogeneous potentialization,and there were no cerebral edema around the tumor.Among 2 cases examined by MRI,T1 weighted image appeared low signal,T2 weighted image appeared high signal.

内容提要三叉神经瘤14例,12例做CT检查,2例做MRI检查,14例术后均经病理检查证实。12例CT扫描呈混杂密度6例,均匀高密度5例,等密度1例,注射造影剂后多呈不均匀强化,肿瘤周围均无脑水肿。2例MRI图像T1加权像呈低信号,T2加权像呈高信号。X线平片示11例有岩骨、颅底骨吸收破坏。

To be qualified as an EOS, the tumor must (1) arise in the soft tissue and not be attached to bone or periosteum,(2) have a uniform sarcomatous pattern ( to exclude the possibility of a mixed malignant mesenchymal tumor),(3) produce osteoid and/or cartilage matrix.

本病的诊断标准是(1)发生于软组织而与骨及骨膜部不相连;(2)具有一致的骨肉瘤表象,以排除混合性恶性间叶组织肿瘤;(3)可产生骨质或软骨样基质。

Ten cases which were first found showed regular oval shape, 4 of 5 recurred lesions appeared as irregular shape. On bone algorithm reconstruction of CT, 11 lesions revealed heterogenous "ground-glass like" mild hyperdensity or hyperdensity masses compared with brain tissue with cystic areas, stippled calfication was seen in 1 cases, the typical eggshell like bony capsule in 7 cases, 5 cases under it showed ring or arc hypodensity line.

CT表现:11例于骨窗上均呈密度不均匀的&磨玻璃&样略高密度或高密度肿块影,内部均可见大小不等的囊变区,1例伴点状更高密度钙化影,7例肿瘤周边可见特征性&蛋壳样&骨壳形成,其中5例于其内侧可见到环形或弧线形底密度影。

Severity of joint swelling, radioimmunoassay of serum estradiol (E 2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once we...

结果:切除卵巢的小鼠,血中雌二醇水平明显下降,而血清骨钙素和肿瘤坏死因子的含量则显著增加;同时,滑膜组织炎症加重,软骨损伤及骨的破坏均更为严重。

Methods: The mice for experiment were immunizied with subcutaneous injection of type Ⅱ collagen to induce arthritis after ovariectomy. Severity of joint swelling, radioimmunoassay of serum estradiol (E2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once weekly.

切除小鼠卵巢后,Ⅱ型胶原皮下注射以诱导关节炎;每周1次观察小鼠的关节肿胀程度;组织切片光镜下观察小鼠滑膜、关节软骨及骨的改变;放射免疫法检测小鼠血清雌二醇、骨钙素、肿瘤坏死因子的变化。

Osteosarcoma is one of the commonest primary malignant tumors of bone. It metastasizes fast, and has a high death rate.

骨肉瘤是原发于骨的肿瘤中最常见的一类恶性肿瘤,转移快,死亡率高。

MethodsBone resorption test was carried out using neonatal mouse calvaria to investigate the bone resorbing activity of cytokines (IL 1, IL 6, TNF, GM CSF, and IFN γ).

利用新生鼠头顶骨进行体外骨吸收实验,分别验证细胞因子白细胞介素1(IL 1)、白细胞介素6(IL 6)、肿瘤坏死因子、IFN γ、粒巨噬细胞生长因子在体外对骨吸收的影响。

Methods Bone resorption teat was carried out using neonatal mouse calvaria to investigate the bone resorbing activity of cytokines (IL-1, IL-6, TNF, GM-CSF, sod IFN-γ).

利用新生鼠头顶骨进行体外骨吸收实验,分别验证细胞因子白细胞介素1、白细胞介素6(IL-6)、肿瘤坏死因子、IFN-γ、粒-巨噬细胞生长因子在体外对骨吸收的影响。

Methods 426 cases of bone sarcomas in Cancer Center of Sun Yat-sen University, China between 1964 and 2003 were reviewed retrospectively.

方法回顾1964—2003年于中山大学肿瘤防治中心治疗的426例骨肉瘤患者,其中15例诊断为鼻咽癌放疗后骨肉瘤。

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