骨硬化

In vivo, CD11b+-cre/Dicer-null mice had mild osteopetrosis due to decreased osteoclast number and bone resorption.

体内实验发现，由于破骨细胞数目减少以及骨吸收作用降低，CD11b+-cre/Dicer-null小鼠表现出轻微的骨硬化症。

Results Early signs of ANFH using CT showed that, in 38 femoral heads 31 cases, there were radiate star shape of high-density osteosclerosis of the trabeculae in 13 femoral head.

结果：早期ANFH的CT表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的"星状征"，骨小梁境界清楚、锐利，属Ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属Ⅱ期；并有5个股骨头在Ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属Ⅲ期。

Results Early signs of ANFH using CT showed that, in 26 femoral heads in 21 cases, there were radiate star shape of high-density osteosclerosis of the trabeculae in 8 femoral head.

结果 CT早期表现：2 1例 2 6个股骨头，其中 8个股骨头骨小梁呈放射状密度增高的"星状征"，骨小梁境界清楚、锐利属Ⅰ期；18个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属Ⅱ期；并有 3个股头在Ⅱ期影像改变基础上出现软骨下骨折及轻微塌陷，属Ⅲ期。

Result:all the cases were diagnosed as early anfh by x-ray film in 35 sites,stage i showed osteoporosis and osteosclerosis in 15 sites,stage ii showed osteosclerosis and cystic hyalomere in 20 sites.56 cases of early anfh were discovered by ct in 43 sites.stage i stelliform sign distortion and osteoporosis and osteosclerosis in 17 sites,stage ii showed meniscus sign was 26 sites.

结果：全部患者x线平片诊断早期anfh共35个部位，其中ⅰ期占15个，x线表现为骨质疏松及骨硬化；ii期20个，表现为骨硬化和囊状低密度区。ct发现早期anfh共43个部位，其中i期占17个，表现为组成骨小梁星芒结构消失，骨质疏松变和骨硬化；ii期26个，表现为囊状低密度区及骨硬化。

Results Early signs of ANFH using CT showed that, in 38 femoral heads 31 cases, there were radiate star shape of highdensity osteosclerosis of the trabeculae in 13 femoral head.Twentyfive femoral heads showed osteosclerosis and trabeculae structure disappearing and vague,incoordinately lowostedensity area and cyst change.There were fracture under the cartilage and light subsid in 5 cases.

结果：早期ANFH的CT表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的"星状征"，骨小梁境界清楚、锐利，属Ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属Ⅱ期；并有5个股骨头在Ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属Ⅲ期。

Results Early signs of ANFH using CT showed that, in 38 femoral heads 31 cases, there were radiate star shape of highdensity osteosclerosis of the trabeculae in 13 femoral head.Twentyfive femoral heads showed osteosclerosis and trabeculae structure disappearing and vague,incoordinately lowostedensity area and cyst change.There were fracture under the cartilage and light subsid in 5 cases.The cases in stage Ⅰwere given decompression, while the pationtsresul in stageⅡand stageⅢ were given decompression and ostetransplant.

结果：早期ANFH的CT表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的"星状征"，骨小梁境界清楚、锐利，属Ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属Ⅱ期；并有5个股骨头在Ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属Ⅲ期。

objective to evaluate early signs of avascular necrosis of femoral head in adult by ct and to guide clinical treatment.methods the cases with suspicious diagnose of anfh were scaned in the both hip joints by x ray and ct to find the early signs of anfh with ct.results early signs of anfh using ct showed that, in 38 femoral heads 31 cases, there were radiate star shape of high density osteosclerosis of the trabeculae in 13 femoral head.twenty five femoral heads showed osteosclerosis and trabeculae structure disappearing and vague,incoordinately low ostedensity area and cyst change.there were fracture under the cartilage and light subsid in 5 cases.the cases in stage ⅰwere given decompression, while the pationtsresul in stageⅱand stageⅲ were given decompression and ostetransplant.conclusion ct results show that the sign of the high osteodensity and low osteodensity and cyst change can disply early anfh.

摘 要］目的：探讨成人股骨头缺血性坏死的早期ct征象并指导临床治疗。方法：对临床疑诊anfh的全部病例均行x线平片及ct检查，分析anfh的早期ct征象。结果：早期anfh的ct表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的"星状征"，骨小梁境界清楚、锐利，属ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属ⅱ期；并有5个股骨头在ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属ⅲ期。治疗结果：ⅰ期行钻孔髓内减压术，ⅱ、ⅲ期行钻孔减压植骨术。

Results Early signs of ANFH using CT showed that, in 38 femoral heads 31 cases, there were radiate star shape of high density osteosclerosis of the trabeculae in 13 femoral head.Twenty five femoral heads showed osteosclerosis and trabeculae structure disappearing and vague,incoordinately low ostedensity area and cyst change.There were fracture under the cartilage and light subsid in 5 cases.The cases in stage Ⅰwere given decompression, while the pationtsresul in stageⅡand stageⅢ were given decompression and ostetransplant.

结果：早期ANFH的CT表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的"星状征"，骨小梁境界清楚、锐利，属Ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属Ⅱ期；并有5个股骨头在Ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属Ⅲ期。

OA, on the other hand, is considered as a disease of cartilage failure with secondary bone changes, such as osteophytes and subchondral sclerosis.

另一方面，骨关节炎一般咸被认定为一种软骨退化性疾病，过程中伴随著骨变如骨以及软骨下骨硬化等。

objective to evaluate early signs of avascular necrosis of femoral head in adult by ct and to guide clinical treatment.methods the cases with suspicious diagnose of anfh were scaned in the both hip joints by x ray and ct to find the early signs of anfh with ct.results early signs of anfh using ct showed that, in 38 femoral heads 31 cases, there were radiate star shape of high density osteosclerosis of the trabeculae in 13 femoral head.twenty five femoral heads showed osteosclerosis and trabeculae structure disappearing and vague,incoordinately low ostedensity area and cyst change.there were fracture under the cartilage and light subsid in 5 cases.the cases in stage ⅰwere given decompression, while the pationtsresul in stageⅱand stageⅲ were given decompression and ostetransplant.conclusion ct results show that the sign of the high osteodensity and low osteodensity and cyst change can disply early anfh.

摘 要］目的：探讨成人股骨头缺血性坏死的早期ct征象并指导临床治疗。方法：对临床疑诊anfh的全部病例均行x线平片及ct检查，分析anfh的早期ct征象。结果：早期anfh的ct表现：31例38个股骨头，其中13个股骨头骨小梁呈放射状高密度的&星状征&，骨小梁境界清楚、锐利，属ⅰ期；25个股骨头表现为骨硬化，骨小梁结构消失、模糊不清，骨密度减低及囊性改变，属ⅱ期；并有5个股骨头在ⅱ期影像学改变基础上出现软骨下骨折及轻微塌陷，属ⅲ期。治疗结果：ⅰ期行钻孔髓内减压术，ⅱ、ⅲ期行钻孔减压植骨术。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。