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The sample particles studied in this project include human red blood cells, osmotically swollen into a micro-sphere, with and without treating with N-ethylmaleimide, and at different temperatures, as well as liposomes with different DOPC/cholesterol ratio (1:1 vs.1:3) For spherical RBCs, smaller deformation were observed in samples at room temperature with NEM treatment and samples at 42 ℃without NEM treatment, compared with the deformation of the control set, namely, RBCs at room temperature without NEM treatment.

这可能是由於42 ℃为红血球细胞骨架Spectrin的型态转换温度,Spectrin由tetramer转换成dimer。推测此温度及药物作用下对Spectrin的型态转换可能造成类似的效果。同时以自行合成DOPC/胆固醇比例(1:1)及(3:1)之微脂粒重覆上述之形变实验,发现两种组合比例微脂粒形变率的差异在误差范围内。

METHODS: Osteoblastic cells from rats were incubated in the medium supplemented wiht rhgh at different doses (10, 200 μg/L), and then the changes of cytoskeleton and cell cycle were detected.

用浓度为10和200 μg/L的重组人生长激素加入大鼠OB培养体系,观察对大鼠OB的细胞周期及细胞骨架的影响。

Three single crystals of N-nitrobenzene, N-acyl dehydroabietic hydrazine 7c single water compounds, N, N-acyl dehydroabietic hydrazine 7l and 2,5 - dehydroabietic-1, 3,4 - oxadiazole 8g were obtained for the first time. X-ray diffraction analysis of these crystals showed dehydroabietic acid skeletons were contained in these crystal molecules.

首次得到N-去氢枞基,N-对硝基苯基双酰肼7c一水化合物、N,N-二去氢枞基双酰肼7l和2,5-二去氢枞基-1,3,4-噁二唑8g 3个单晶,并用X射线单晶衍射进行了解析,晶体中均含有去氢枞酸分子骨架

All the results indicated:the molecular mechanism for embryoes abortion mediated by calcium may be relevant to some genes, which controlling assenergy transfering oxidoreduction system endomembrane system and cytoskeleton structure system ,transcripted or expressed unnomally.

由以上研究结果初步可以认为:受钙胁迫花生幼胚败育的分子机理可能是与早期幼胚内与能量转化、氧化还原系统运转、细胞内膜以及细胞骨架功能维持相关的功能基因的转录和表达异常有关。

Various log and core data are used to estimate the petrophysical parameters such as porosity and permeability, and to define the distribution and petrophysical properties of the framework sandbodies in each formations of the PermoCarboniferous in the Bohai Bay basin.

应用录井、测井及岩心资料,测定了孔隙度、渗透率等物性参数,查明了渤海湾盆地石炭-二叠系各地层组的骨架砂岩展布特征及其物性特征;应用相比法编图对渤海湾盆地石炭纪、二叠纪岩相古地理进行了恢复,研究了沉积相对储层及其物性特征的控制作用。

The selectivity of phenylacetaldehyde is increased when Br〓nsted acidity is getting stronger. The selectivity of benzaldehyde can be increased by increasing the amount of extraframework titanium species.

分子筛的B酸中心强度对产物分布有着显著的影响,B酸越强,苯乙醛的选择性越高,B酸位是催化环氧苯乙烷定向重排生成苯乙醛的催化活性中心;非骨架钛物种的增加有利于苯甲醛的生成。

Correlation coefficient: 0.9962 . Positively charged'free'complex ions should be readily quenched by 〓, but when it is bound to DNA, it can be protected from the quencher because the highly negatively charged 〓 would be repelled by the negative DNA phosphated backbone, hindering quenching of the emission of the bound complex.

从理论上讲,带正电的配合物的阳离子应该可以被大阴离子淬灭,但是在DNA存在下,金属配合物插入到DNA的碱基对中,而〓被带负电荷的DNA磷酸骨架强烈排斥,从而避免了〓的淬灭,因此大的Stern-Volmer曲线斜率相应于对配合物较弱的保护形式。D。

Melatonin ; evolution ; photoperiodic signal ; free radical ; cytoskeleton

褪黑素;生物进化;光周期信号;自由基;细胞骨架

Tetrahydroisowuinolin derivatives and phthalide derivatives were designed and synthesized on the basis of a PDE4 inhibitor pharmacophore model set up through computer simulation. Some tetrahydroisowuinolin derivatives synthesized were evaluated on their activity against PDE4 for study on the structure-activity relationship.(7-cyclopentyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155) and Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (170) showed good activity against PDE4, which were chosen as the lead compounds to design and synthesize another analogs in order to develop selective PDE4 inhibitors with better activity.

分别设计合成了以四氢异喹啉和氨基苯酞为骨架的两类小分子杂环化合物,并对部分四氢异喹啉衍生物测试了其相关的生物活性,初步确定了其构效关系,发现了两个对PDE4有较好抑制活性的先导化合物(7-cyclopentyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155)和Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (170)。

Any of numerous fishes of the class Chondrichthyes,characterized by a cartilaginous skeleton and placoid scales and including the shark s,rays,and skates.

属软骨鱼纲的鱼软骨鱼纲鱼的一种,以软骨骨架和板状鱼鳞为特征,包括鲨、鳐、灰鳐

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。