骨架

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性（过度刺激神经元上的递质受体）、钙紊乱、炎症、能量和生长因子缺乏作用下，敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关，还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用，影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Objective To investigate the influencing factors on preparation of 5-amino salicylic acid loaded calcium pectinate pellets by excursion-spheronizing method,and to evaluate the micromeritic properties and the drug release behavior for the resultant pellets .

目的考察含有5-氨基水杨酸的果胶钙骨架微丸的制备过程的影响因素以及微丸的粉体学性质与释药特征。

Results Ketoprofen calcium pectinate gel beads and calcium alginate gel beads showed excellent drug release pattern and mucoadhesiveness. Ketoprofen released from calcium pectinate beads mainly through diffusion behaviors, whereas the release of ketoprofen from calcium alginate gel beads was ruled by corrosion of carrier material.

结果 酮洛芬果胶钙凝胶小球和酮洛芬海藻酸钙凝胶小球均具有良好的生物黏附性能，果胶钙凝胶小球主要通过溶胀作用缓慢释药，而海藻酸钙凝胶小球的释药与凝胶小球慢慢吸水后骨架溶蚀有关。

In this paper,the oxidation of pentane with hydrogen peroxide has been carried out over TS zeolite.

XRD、IR和氧化反应数据证明了戊烷氧化反应的活性是由于Ti进入分子筛骨架的结果。

Aluminum panels are incorporated into this skeleton to form a positive connection and perform a load-bearing role.

铝面板纳入本骨架，形成一个积极的连接，并执行一个承重的作用。

The elaboration of a double pergola that formalizes the link between the commercial area and the residential area and provides a scaffold for attaching city and community programs

这两条廊架亦成为界定公共空间的骨架，城市性机构和社区性设施分别设定在廊架之后。3。

The influence of ultrasonic treatment on accessibility and oxidation reactivity of MCC with periodate sodium was investigated.

氧化纤维素是制备不含葡萄糖环骨架的新型纤维素衍生物的原料，利用醛基的反应可以获得具有荧光、储能、尿素吸附剂以及生物医用等功能的高分子材料。

Ironically, the park is littered with billboards proclaiming the owners' desire to protect wildlife. At the end of their tour of the park, visitors are directed to a 'science hall' where a complete tiger skeleton is displayed in a Perspex case.

讽刺的是，公园充满了业主要保护野生动物的宣传广告牌，在游客即将结束观光公园的时候，被引导到一个有机玻璃箱内封存著一个完整的老虎骨架的'科技厅'内。

Indeed, they found six compounds that did just that, five of which were known to perturb the cell's cytoskeleton, that is, the scaffolding that gives a cell its structure.

事实上，他们发现了6个化合物，这正是做到了这一点， 5 ，其中已知干扰细胞的细胞骨架，即是棚架，使细胞结构。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。