骨折学

And it was divided into four groups at randomly (n=6),The vertical compression,bending and torsion intensity in without and with reduction of cortical fragment of plate fixated contra side, without and with reduction of cortical fragment of plate fixated sidewere measured.A11 results were analyzed with statistic method.2、animal experiment :The 12 adult goats were divided into two group at randomly,wedged cortical defect with 1 cm of long and conjugate diameter was created in the middle-part of the medial femur and plate was fixed in the defect side and as the experimental side,the other side was control.after operation 4、8、12 weeks,investigation of the fracture healing by means of gross observation,X-ray examination and histology in both sides.

测试各组的垂直压缩、三点弯曲及抗扭转的刚度。2、动物实验：12只健康成年山羊，雌雄不限，体重在20～25kg之间，在同一只羊双侧股骨中段内侧制造楔形骨皮质缺损，分实验组和对照组两组进行钢板内固定并植骨，于术后4、8、12周对实验组及对照组行X线正位片检查，观察骨折愈合过程中不同时间点的影像学特点。于4、8、12周各组处死4只动物行大体标本观察，并取缺损区骨组织行组织学检查。X线检查及组织学检查结果根据LaneX线评分标准及组织学评分标准进行评分。最后采用SPSS13.0进行统计学分析。

Second: Comparetive study of ordinary X-ray film, CT and 3D-CT in the jaws fractures. Ordinary X-ray film, CT and 3D-CT was performed in 61 cases of jaws fractures. The diagnosis of these three imaging methods was compared with each other and with the operation findings. The result shows that the fractures in body and angle part of mandibal could be shown excellently by all these imaging methods. 3D- CT is the best method in showing the mandibular fractures. Ordinary X- ray film is poor, and the accuracy of CT and 3D-CT is similar in showing the macxillary fractures.

二。颌骨骨折的常规X线、CT和三维CT对比研究：通过对61例不同类型的上、下颌骨骨折常规X线、CT和三维CT显示情况的对比分析，同时与手术结果相对照，结果表明对下颌骨体部和角部的骨折三种影像学检查均显示准确；对下颌骨髁状突骨折的显示三维CT优于CT和常规X线；对上颌骨骨折的显示常规X线显示较差，CT和三维CT显示准确率相似。

We assess the anatomical result of distal radius after clinical union of fracture according to the scoring system based on the modification by Sarmiento et al(1980), and function scores of affected wrist at pretherapy 、2nd week 、4th week 、8th week according to the points system of Gartland and Werley modified by Sarmiento(1975). The anatomical result was divided into 4 group : excellence, good , fair, poor.

在课题研究过程中，根据Sarmiento影像学评分标准和Sarmiento改良的Gartland and Werley腕关节功能评分标准，测量Colles关节内骨折临床愈合后的影像学评分和治疗前、第2周、第4周、第8周的功能评分，其中影像学评分按分数高低分为优、良、差、极差4个解剖等级。

objective the purpose of this study was to summarize our experience of the application of internal rigid fixation with miniplate to treatment of mandibular fractures.methods a retrospective analyisis of clinical data of 67 cases,who had experienced the anatomic reduction and rigid fixation by using miniplate.with the help of maxillomandibular distraction pre operation and post operation and temporary maxillomandibular fixation during operation,the fracture bones were smoothly reduced and fixed.results clinical and radiographic examination showed that all cases gained good clinical results and precise anatomic alignment of fracture postoperatively without infection,malocclusion,bone malunion or other complications.conclusion mocortical miniplate fixation of the mandible is a reliable and effective techinique providing rigid fixation and an ideal modality for the treatment of mandibular fractures.combined with maxillomandibular fixation.

对67例下颌骨骨折患者的临床资料进行回顾总结，所有患者应用小型接骨板行坚固内固定治疗。其中7例颏部骨折，12例颏旁骨折，16例颏孔区骨折，9例体部多发性骨折，5例体部粉碎性骨折；18例合并其他部位骨折。所有患者术前经临床检查和影像学检查明确骨折的位置和骨折线的数目后，分段牙弓夹板结扎、颌间弹性牵引，使移位的骨折段逐渐复位；术中经口内切开复位、细钢丝颌间结扎、小型接骨板坚固内固定；术后行临床检查和影像学复查，必要时颌间弹性牵引7～10 d。结果所有患者手术切口ⅰ期愈合，治疗效果满意；临床检查所有患者牙合关系良好、面部对称；影像学复查证实骨折线对位良好。结论经口内切开小型接骨板坚固内固定辅以颌间固定治疗下颌骨骨折效果可靠，术后并发症少，是一种理想的手术方法。

Abstract］ objective to provide the experience on treatment with the internal fixation to the fractures combined with/without dislocation on peripheral amphiarthrodial joint.methods from january 2000 to january 2005,62 cases were follow-up visited and evaluated on imageology,imaging,joint function and complication,et al.results serveral problems were observed on these cases.first,when the internal fixation were pulled out,some of the patients were observed the disturbance,even loss on joint function,and their quality of life were limmited.second,some internal fixations had been broken before they were pull out.conclusion we should sufficiently allow for not only the stabilization and the union of the fracture,but also degrade the complication to minimum limit and maximally recover the joint function.

目的 通过对微动关节周围骨折和合并关节脱位的内固定治疗后的疗效分析，进而为临床治疗提供经验。方法对2000年1月～2005年1月期间62例患者进行随访，并从影像学及关节功能、并发症等方面进行评估。结果治疗该类创伤病例存在着以下几个问题：（1）部分患者的关节功能在内固定解除术后，存在着不同程度的功能障碍，甚至丧失而影响到患者的生活质量。（2）并发内固定断裂情况时有发生。结论治疗微动关节周围骨折尤其在合并有关节脱位时，应充分考虑到既要修复因创伤引起的骨折使其愈合并使该关节稳定，又应该最大限度地恢复关节功能，并将并发症降低到最小限度。

Abstract］ objective to provide the experience on treatment with the internal fixation to the fractures combined with/without dislocation on peripheral amphiarthrodial joint.methods from january 2000 to january 2005,62 cases were follow-up visited and evaluated on imageology,imaging,joint function and complication,et al.results serveral problems were observed on these cases.first,when the internal fixation were pulled out,some of the patients were observed the disturbance,even loss on joint function,and their quality of life were limmited.second,some internal fixations had been broken before they were pull out.conclusion we should sufficiently allow for not only the stabilization and the union of the fracture,but also degrade the complication to minimum limit and maximally recover the joint function.

作者：洪洋，陈峥嵘，董有海，钱光，杨群，程根祥目的通过对微动关节周围骨折和合并关节脱位的内固定治疗后的疗效分析，进而为临床治疗提供经验。方法对2000年1月～2005年1月期间62例患者进行随访，并从影像学及关节功能、并发症等方面进行评估。结果治疗该类创伤病例存在着以下几个问题：（1）部分患者的关节功能在内固定解除术后，存在着不同程度的功能障碍，甚至丧失而影响到患者的生活质量。（2）并发内固定断裂情况时有发生。结论治疗微动关节周围骨折尤其在合并有关节脱位时，应充分考虑到既要修复因创伤引起的骨折使其愈合并使该关节稳定，又应该最大限度地恢复关节功能，并将并发症降低到最小限度。

Results:Fractures in body,angle and ascending branch of mandible could be showed fine by all these imaging methods. 3D-CT was better than 2D-CT and conventional X-ray plain film in diagnosis of fractures in condyle and coronoid process. Conventional X-ray plain film was poor in diagnosis of the maxillary fractures.2D-CT and 3D-CT were similar in diagnosis of the maxillary fractures.3D-CT showed the jaws fractures directly and stereoscopicly.

结果：对于下颌骨体部、角部和升支骨折，三种影像学都能很好的显示，对于髁状突和喙突骨折，三维CT检查优于常规X线和二维CT；常规X线显示上颌骨骨折较差，而二维CT和三维CT显示的准确性比较接近。

The hypertrophic chondrocytes showed negative signal and the osteoblasts stained strongly in the endochondral ossification period.These results suggested that the expression of TGF-β1 was closely related to the proliferation and differentiation state of repair cells.Conclusion TGF-β1 is intimately involved in the control of fracture healing.

TGF-β1表达量和组织学分布的变化与骨折愈合过程中相应的组织学变化密切相关，而且与相应细胞的功能状态相关，说明TGF-β1是调节骨折愈合过程的重要因子。

Methods:Animal models of 25 adult mixed breed dogs were established by transverse osteotomy at bilateral iliopectineal crest,which were fixed with ATMFS anterior column connector and steel plate respectively. The animals were examined at 2,4,6,8,and 12 weeks by X-ray,macropathological observation and biomechanical test. Tetracin fluorescent labeling,HE staining,Masson triad colour staining,in situ hybridization and immunohistochemical method were performed and histological image analysis were applied.

建立犬双侧骨盆弓状线骨折的动物模型，分别采用ATMFS前柱固定器和5孔重建钢板内固定，于术后2、4、6、8、12周分别行影像学检查、大体观察及生物力学测试；采用四环素荧光标记法、HE染色、Masson三色染色法、原位杂交法、免疫组织化学法进行组织学观察并图像分析；采用RT-PCR法检测骨折端不同时期骨钙蛋白和核心转录因子mRNA相对表达量的变化。

Through simulation of the real process of thomcolumbar burst fracture and use of modem dynamics techniques, the present study was (1) to investigate the kinetic relationship between structural damage and impact energy absorption and dynamics mechanism of thoracolumbar burst fracture by quantitative analysis of various injured segments;(2) to explore the instability mechanism of L1 vertebral burst fracture and its injury threshold by three-dimensional analysis of the injured segment with stereophotogrammetry in combination of transient physical parameters, anatomy and image;(3) to explore the corresponding relationships between impact energy, geometry parameters and biomechanics by geometry and biomechanical analysis of thoracolumbar burst fracture, which may provide an objective standard for evaluation of spinal injury severity and experimental evidence for adoption of biomechanical treatment in clinic;(4) to evaluate the fixation effect of different instruments and the effect of intervertebral bone graft on segment fixation by analysis of the threedimensional stability of different internal fixation instruments and their decompression of the spinal canal, which may provide experimental evidence for therapeutical selection for thoracolumbar burst fracture in future; and finally to investigate the effect of various instrument fixation on dynamical characteristics by comparison and quantitative analysis of frequency and amplitude responses, which may provide certain theories and experimental evidence for application of vibration test to judge the stability of the spine.

本研究从胸腰段脊柱爆裂骨折发生的实际过程出发，以现代动力学检测及计算机多通道高性能数据采集分析系统等高新技术为基础，实时量化分析损伤节段的工程参数，揭示了结构破坏与能量吸收的变化规律，探讨了胸腰段脊柱爆裂骨折的瞬态损伤机制；利用三维立体摄像技术，对不同损伤程度的节段进行三维运动分析，结合瞬态物理参数、影像学和病理解剖，明确了〓椎体爆裂骨折的失稳机制及损伤阈值；通过对胸腰椎爆裂骨折的几何学变化及生物力学分析，明确了撞击能量与几何参数、几何参数与生物力学的相应关系，为评判脊柱损伤程度提供了客观标准，为治疗中采取适宜的生物力学方法提供了实验依据；通过对比分析不同内固定器械的三维稳定性和对椎管的减压作用，评价不同器械的复位固定作用，同时比较椎体间植骨对节段固定作用的影响，为今后临床胸腰段脊柱爆裂骨折的治疗选择提供依据；利用振动测试与分析技术，比较及量化分析了不同致伤状况的频幅响应特征，比较分析了各种器械固定对动力学特性的影响，为今后临床建立基于振动测试与分析技术判断脊柱稳定性的诊断方法，提供了一定的理论和实验依据。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。