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Objective To study the relationship between IL-1,MMP-13and pathogenesis of knee osˉteoarthrosis.Methods IL-1and MMP-13were measured concurrently in synovial fluid samples from23patients with mild OA,28patients with severe OA and6patients with disciform meniscus.The determinations of positive rate of cells in genual synovium with IL-1and MMP-13were carried out using immunohistochemical techonology.

目的 探讨白细胞介素-1(IL-1)、基质金属蛋白酶-13(MMP-13)在膝关节骨性关节炎发病中的作用方法提取23例OA病变轻微患者、28例OA病变严重患者、6例对照者的滑膜组织及关节液,采用免疫组织化学方法检测膝关节滑膜组织中IL-1、MMP-13的阳性细胞率及通过夹心ELISA法测定膝关节滑液中IL-1、MMP-13含量。

Methods and Results 194 cases of genual osteoarthritis were randomly divided into tuina group, plaster compress group and combined group, The general effective rate of the tuina group is 80.00%, the plaster compress group is 81.25%; and that of the combined group is 88.54%, but the Control group is 80.56%.

方法与结果采用随机分组方法,将194例骨性膝关节炎患者分为观察组、推拿组和药敷组,研究结果表明:推拿结合药敷治疗组治疗的总有效率为88.54%,单纯推拿治疗组的总有效率为80.00%,药敷组的总有效率为81.25%。

Methods The imaging features of nine patients who refused amputation and chose to be treated with Chinese herbal medicine were observed. Of the patients, four were confirmed pathologically, two were found to have pulmonary metastasis at diagnosis, one of femur osteo-genic osteosarcoma with osteogenic metastasis was found in the epiphysis of the homolateral tibia, and the other two were proved to have no possibility of other diseases by radiological specialists to demonstrate the imaging diagnosis of osteosarcoma.

观察拒绝截肢采用中药治愈的9例骨肉瘤影像学表现,其中4例经活检病理证实,2例诊断骨肉瘤时肺部已发现转移,1例股骨成骨型骨肉瘤同侧胫骨骨骺内有成骨性转移,另外2例经影像学专家按举证倒置程序,论证骨肉瘤的影像学诊断,排除了其他病变的可能。

There are more than two dozen reported cases of lumbar facet dislocation after rapid deceleration injuries (e.g., traffic accidents), most involving L5 S1.61,112 115 The mechanism of injury in these cases is purported to be a combination of hyperflexion, distraction, and rotation.61,112,116 In a posthumous study conducted in 31 lumbar spines of subjects who died of traumatic injuries,Twomey et al.117 found occult bony fractures in the superior articular process or subchondral bone plate in 35% of victims, and z-joint capsular and/or articular cartilage damage in 77% of cases.

多项研究报道了急性减速伤后发生腰椎小关节分离,多数发生于L5-S1,其机制可能为过度屈曲,分离和旋转。在一项对死亡病例的研究中,Twomey 等发现,31例因交通事故死亡的人中有35%的腰椎上关节突或软骨下骨性终板存在隐匿骨折,77%存在小关节囊和/或关节软骨损伤。

Only the front waist of the abdominal cavity and soft iliopsoas, only in the vicinity of some of the muscles, ligaments and fascia, and other non-bony structures of protection, or lack of coordination in the weight-bearing exercise, vulnerable to injury.

腰部前方只有松软的腹腔和髂腰肌,附近仅有一些肌肉、筋膜和韧带等无骨性结构的保护,因此在负重或不协调的运动中,极易受到损伤。

Methods Levels of IL-6,IL-8,sIL-2R and TNF-a in serum from 30 JRA patients and 34 RA patients,in the synovial fluidfrom 4 JRA patients,7 RA patients,6 osteoarthritis patients and 9 meniscitis patients were detected by sandwich ELISA.

方法采用夹心 ELISA法,对 30例 JRA 和 34例 RA患者的血清中, 4例 JRA、 7例 RA、 6例骨性关节炎和 9例半月板损伤患者的关节液中 IL-6、 IL-8、 sIL-2R和 TNF-α的水平进行检测。

Results. Solid bony fusion and the improement of paraparesis were achieed 2 years and 1 month after the surgery. He is now able to feed himself and to walk with a cane, both without assistance.

结果:术后两年零一月的随访,患者以获得坚强的骨性融合,下肢轻瘫症状得到改善,目前患者能够自行进食和在拐杖的帮助下行走。

Pathological changes of bone and periarticular abnormalities have been recorded to account for osteomalacia, osteoporosis, spontaneous fractures, adult rickets,steoarthritis,osteochondritis dissecans, chrondo calcinosis, subchondral cyst formation, and azure lunulae of the fingernails.

骨的病理改变和关节周围的异常可以用来解释骨软化症,骨质疏松症,自发性骨折,成人佝偻病,骨性关节炎,分离性骨软骨炎,钙质沉着症,软骨下囊形成,指甲的天蓝色弧形影。

Lateral neck of vertebra's internal fixation can rectify frift, recovery spinalis physiologic radian, increase confluens rate of bone graft and elevate curative effect.

椎弓根内固定可矫正滑移,恢复脊柱的生理弧度,达到即刻稳定,增加植骨的融合率,提高手术疗效。而植骨方法的不同对椎间骨性融合成功与否关系极为密切。

There is a kind of special protein in synovial fluid of patient's knee joint with osteoarthritis.

膝关节骨性关节炎患者的膝关节滑液中产生了特异性的蛋白质,这种蛋白质在健康人的膝关节滑液中不存在。

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