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At 12–15 years, Charnley reported continuous radiolucent demarcation around cemented cups in 14% of patients.40 The failure rate was greatest in young patients, and Barrack and colleagues reported 44% loosening of cemented sockets at 12 years in individuals younger than 50 years.54 Cementless acetabular cups are hemispherical in shape and most are entirely porous-coated for bone ingrowth.

术后12-15年时,Charnley在14%患者中发现骨水泥髋臼杯周边存在连续的透亮线。年轻患者中假体失败率最高,Barrack报道为小于50岁的患者中术后12年时44%发生骨水泥套松动。非骨水泥髋臼杯为半球型,大部分全层喷涂多孔表面以促进骨长入。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.recently,tumor vessel angiogenesis has been the warm spot of research.genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.the correlated research has very important significance for judging gct prognosis and guiding therapy.

骨巨细胞瘤(giant cell tumor of bone,gct)是一种常见骨肿瘤,由于其高复发率和强侵袭性,备受临床骨科工作者的关注。骨巨细胞瘤血管生成是近年来研究热点,实体瘤的发生、发展及转移与肿瘤的血管生成密切相关;细胞外基质降解在肿瘤的浸润和转移中起到关键作用;肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。骨巨细胞瘤生物大分子研究的不断深化对判断gct的预后及指导治疗有重要意义。

Roentgenography, histological and electronic microscope examination was used to compare the osteogenesis effects of each group.

结果实验组骨缺损无论是骨痂出现还是骨连接发生时间均较对照组明显提前,空白组骨缺损形成骨不连。

Roentgenography,histological and electronic microscope ex-amination was used to compare the osteogenesis effects of each group.

结果 实验组骨缺损无论是骨痂出现还是骨连接发生时间均较对照组明显提前,空白组骨缺损形成骨不连。

Methods 11 cases of old scaphoid fracture nonunion were treated by transplantation of reversed fascia pedicled bone graft from styloid process of the radius and implantation of bone morphogenetic protein and fibrin sealant complex.

对11例腕舟骨陈旧性骨折骨不连,采用带筋膜蒂逆行桡骨茎突骨瓣移植及骨形态发生蛋白(bone morphogenetic protein,BMP与纤维蛋白( fibrin sealant,FS)复合物植入的手术方法治疗。

Results The results revealed that the bone defect in the experimental group had excellent repair than that seen in the control and blank group, both bone union and the period of bone mature were earlier than that seen in the control and blank groups. There was fibration in the blank group at 12th week.

结果实验组骨生成情况优于对照组,无论是骨连接发生时间还是骨成熟时间,实验组均较对照组提前2周左右,同期骨生成量也明显多于对照组,而空白组缺损内主要形成纤维组织。

Posterolateral Lumbar Intertransverse Process Spinal Arthrodesis With Composites Composed Of Recombinant Human Bone Morphogenetic Protein 2 And Allograft Or Xenograft; Or With Composite Consisted Of HA And Xenograft in rabbitsBackground: So far spine arthrodesis remains to be used in spine surgery.

中文题名rhBMP-2、HA及其复合物在兔腰椎后外侧融合的实验研究副题名外文题名论文作者杨发军导师马忠泰教授学科专业外科学研究领域\研究方向临床技能训练与研究学位级别博士学位授予单位北京大学学位授予日期2001 论文页码总数92页关键词骨形态发生蛋白异体骨移植脊柱融合异种骨移植馆藏号BSLW /2001 /R687 /42 背景:目前,脊柱融合手术被广泛地应用于脊柱外科领域,自体髂骨仍是被最常用的骨移植物,但是其有5%-35%的不融合率。

aim: to evaluate the feasibility of injectable calcium phosphate cement and fibrin sealant as an injectable compound carrier of bone morphogenic protein .

目的: 了解以注射型磷酸钙骨水泥/纤维蛋白胶共同作为骨形态发生蛋白复合载体的注射型骨修复材料在小鼠体内异位成骨的能力,探讨其作为注射性骨替代物的可行性。

Osteochondromas, or osteocartilaginous exostoses, are the most common primary benign bone tumors and usually occur in the metaphyses of long bones.

骨软骨瘤,或称骨软骨外生骨疣,是最常见的原发性良性骨肿瘤,通常发生于长骨的干骺端。

Abstract] objective to discuss radiological findings of parosteal osteosarcoma on emphasis combined with clinical pathology and literature.methods 4 cases of parosteal osteosarcoma proved by operation and pathology were analyzed retrospectively.results female was 3 cases,male was 1 case,average age was 30.5 years old,these tumors were arised on posterior border of distal femur and popliteal cavity,presented as lobular dense ossified mass,defined lesion.one case had villose margin.a thin narrow lucent zone separated the mass from the cortex at two cases.one case underwent angiography,there was no malignant feature.conclusion parosteal osteosarcoma may be divided into low-grade type and high-grade type.radiological manifestations of early stage possess character,early diagnosis conduces to establish rational treating plan and evaluate prognosis.

目的 结合临床病理学特征和文献资料,重点讨论皮质旁骨肉瘤的x线特征。方法收集经手术、病理证实的皮质旁骨肉瘤病例4例,对其进行回顾性分析。结果 4例患者女3例,男1例,平均年龄30.5岁,肿瘤均发生于股骨远端后侧和腘窝处,表现为分叶状致密骨化肿块,边界清晰,其中1例边缘呈绒毛状改变,2例有细窄透亮带与骨皮质相隔,1例行血管造影,未见血管池等恶性征象。结论皮质旁骨肉瘤分为低度恶性和高度恶性两种,早期影像学表现有特征性,早期诊断有助于制订相应的治疗方案和评估预后。

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