骨化

Therefore,to those patients with ossification of one spinal ligament,whether the other ligaments are involved should be noticed.

因此，对于某一脊柱韧带发生骨化的患者，应注意其是否合并有其它脊柱韧带的骨化。

Results: The profiles of split trace of 40 bone fossil samples respectively from Stegodon orientalis, Chinese rhinoceros, Cervus and other mammalian fauna were identified, some of them were found blunt and might be rodent bite marks.

结果 经40件东方剑齿象、中国犀、鹿等残骨化石标本断裂痕迹剖面的观测，发现有部分骨化石断裂剖面圆钝，似啮齿动物的咬痕，但大部分骨化石断端剖面呈锥形切削改造，有的双面削刮呈锐利器型，有的存在明显打击或铲刮的"印记"，初步认为属早期人类制作骨器的遗迹。

Abstract］ objective to improve the diagnosis of non-ossifying fiboma by analysing its x-ray feature.methods plain x-ray films was performed in all patients.x-ray finding in 8 cases with pathologically-confirmed non-ossifying were analyzed.results the clinical symptom was mild,the lesions occurred usually at the metaphysis of the long bones,the affected bones included femur（n=4）,tibia（n=3）,humerus（n=1）.cortical type was seen in 5 cases,presenting as unilocular or multilacular transparent areas with in the cortex or tightly beneath the cortex,the lesion had a sclerotic margin.which was more obvious at the marrow side.medullary type was seen in 2 cases.the lesion was located at the center of the bone and grew centrally.the tumor was manifested as unilocular or multilocular.tramsparent area with sclerotic border and the bone cortex became thinner with slightly expanding on 11 sides.conclusion plain radiography is the elementally means to detect this disease.based on the typical x-ray signs of non-ossifying fibroma combined with clinical data,correct preoperative diagnosis can be made in most cases.

目的 探讨非骨化性纤维瘤的x线表现以提高诊断水平。方法所有病例均摄有x线平片，分析经病理证实的8例非骨化性纤维瘤。结果临床症状轻，好发于下肢长骨干骺端或骨干，股骨4例，胫骨3例，肱骨1例。皮质型5例，表现为皮质内或紧贴皮质下的单层或多层透亮区，病变向骨内发展进入髓腔，周围有致密硬化带环绕，以髓腔侧明显；髓质型2例，病灶在骨内中央发展，显示为单房或多房透亮区，边缘有硬化，骨皮质菲薄，轻微向周围膨隆。结论 x线为最基本的检查方法，典型病例x线平片结合临床症状即可明确诊断。

Bones undergoing either intramembranous or endochondral ossification are continually remodeled from the time that initial calcification occurs until the final structure appears.

骨通过膜内骨化或软骨内骨化而不断的得以重塑，直至最后结构的形成。

Results］All ossifying fibroma have the feature of benign bone tumor, intracortical osteolysis clearly marginated by a band of sclerosis, inhomogeneous calcification and ossification in the lesion, no periosteal reaction and soft tissue mass. Predominant involvement of the tibia.

结果］长骨骨化性纤维瘤具有一般良性骨肿瘤的特征，表现为骨干骨皮质内的溶骨性破坏区，边缘多有硬化缘，其内可见钙化或骨化影，周边无软组织肿块和骨膜反应，特别是发生于胫骨前端骨皮质的具有上述表现的病灶。

Metaphysis and periphery of the 2nd center of ossification are enhanced more intensely than the central regions of 2nd ossification center. The enhancements in all regions declined with age.

干骺端红骨髓和二次骨化中心周边红骨髓比在骨骺二次骨化中心中央区域的黄骨髓强化更明显，但它们的强化程度均随年龄的增长而逐渐减弱。

Methods From December 2004 to May 2005, 9 cases of bone defectwere repaired with Osteoset pellets; bone defect was caused by benign tumor inlimbs, including 3 cases of fibroma xanthomas in humerus(1 case) and acetabulum (2 cases), 2 cases of bone cysts in humerus(1) and radius(1), 1 case of nonossifying fibroma, 1 case of ossifying fibroma and 2 cases of osteofibrous dysplasia in femurs.

2004年12月～2005年5月，采用Osteoset颗粒作为骨移植材料治疗9例四肢良性肿瘤性骨缺损，其中肱骨黄色纤维瘤1例，髋臼黄色纤维瘤2例，肱骨骨囊肿1例，桡骨骨囊肿1例，股骨非骨化性纤维瘤1例，股骨骨化性纤维瘤1例，股骨骨纤维结构不良2例。

Ossifying fibroma so as to increase the veracities of clinical diagnosis and treatment among the young. Methods Cases of 15 juvenile patients with non??

目的 探讨非骨化性纤维瘤的本质，提高非骨化性纤维瘤的临床诊治准确率。

The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups（P＜0.01）.The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group（P＜0.01,P＜0.05）.The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面，差异均有显著性（P＜0.01）；IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性（P＜0.01）； MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达，差异具有显著性（P＜0.01，P＜0.05），MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达；TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

Objective To discuss the essence of nonossifying fibroma so as to increase the veracities of clinical diagnosis and treatment among the young.

作者：李勇，刘兴炎，黄光海，甄平，田乃宜，曾凡本目的探讨非骨化性纤维瘤的本质，提高非骨化性纤维瘤的临床诊治准确率。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。