骨再生

Renal osteodystrophy is a common complication in patients with chronic renal failure. According to difference in bone turnover rates, it is classified into high turnover renal osteodystrophy, and low turnover renal osteodystrophy (including mixed uremic osteodystrophy, aluminum-induced osteomalacia and adynamic bone disease).

肾骨病变为慢性肾衰竭病患常见之并发症，其传统之分类根据骨周转速率之不同分为高周转型骨病变，及低周转型骨病变（包括混合型肾骨病变，铝中毒引起之骨软化症，及再生不良型骨病变）。

Initial reports hae demonstrated success rates of implants in regenerated bone under function comparable to the success rates of implants placed in natie nonregenerated host bone.

最初的报道已经证实种植于再生骨内的有功能的种植体期其成功率可以媲美在没有植骨的原有骨内的种植体的成功率。

Calcium sulfate has been used for bone regenation in oral medicine. Osteopontin, a marker molecule, expressed by osteoblast, plays multiple roles in human body. However, the effect of calcium sulfate on osteopontin expressed in osteoblasts is unclear. In this study, U-2 osteosarcoma osteoblastic cells were cultured in 0, 0.5, 1, or 10 μM calcium sulfate hemihydrate. There was no effect in the proliferation of cells, suggesting that calcium sulfate up to 10 μM is biocompatible. The cells and conditioned media were collected for analyzing mRNA and protein levels of osteopontin by reverse-transcription polymerase chain reaction and Western blot, respectively.

硫酸钙用於口腔医学中的骨头再生已经有多年历史，骨桥素是一种被骨母细胞分泌且在人体扮演重要多重角色的标的分子，然而，硫酸钙在骨母细胞分泌硫酸钙上的影响仍未明朗，在本实验之中，培养U-2骨肉瘤类骨母细胞(U-2 osteosarcoma osteoblastic cells)於0、0.5、1、10 μM的硫酸钙之中，在细胞数目的复制上，四种硫酸钙浓度并无影响，显示出U-2骨肉瘤类骨母细胞培养於10 μM的硫酸钙仍是生物相容性的。

OBJECTIVE: To verify whether GTR can promote the repair of periodontal bone defect and the formation of new bones and whether combined use of GTR membrane, artificial bone, and growth factors can acquire much more new periodontal tissue.

目的：验证引导组织再生是否可促进牙周骨缺损的修复及增加新骨的形成，将引导组织再生和人工骨，生长因子等生物材料联合使用是否可获得更多牙周新组织。

Based on the principle of the Guided Bone Regeneration , our research will focus on regenerating cleft bone defect and reconstructing the integrity of palate by aid of biodegradable collagen membrane and multi-function biological membrane compounded with human recombinant bone morphogenetic protein .

本研究根据引导性组织再生的原理，通过采用可吸收的胶原膜和复合了人重组骨形成蛋白的多功能生物复合膜技术来引导腭部骨缺损处的骨组织再生，以达到在腭裂外科治疗中，对腭部硬组织重建的要求，为腭裂的后续治疗奠定结构基础。

Electricity micro-circumstance is one of important circumstances that osteoblasts live,which has important signification for bone regeneration and reintegrate under simulating.

电学微环境是成骨细胞所处的重要微环境之一，模拟骨电环境对骨的再生重建及促进种植体骨整合具有重要意义。

Results: Regenerated mandibular segments of over 3cm length were created in all canine models. The bone density and intensity of the central growth zone of regenerated segments were about 15% of the normal part of homolateral mandible in three monthes, and got to about 40% in four monthes, and 60% in five monthes.

结果：各实验犬牵引再生骨段长度均达到3.0 cm以上，术后3个月再生骨中央生长区强度和密度达同侧正常骨段的15%左右，术后4个月时可接近正常骨的40%，术后5个月时可达正常骨密度的60%左右。

Haversion system was clearly observed and matured bone tissues filled the ceramic pores and interconnected with each other. All the result suggested that, taking advantage of"living organic culturing medium"in vivo, culturing composite that consisted of autogenous periostea and biomaterials should be an effective approach to obtain satisfactory bioactive bone substitutes which have the potential to repair load-bearing bone defects clinically.

上述研究表明，1、双相多孔TCP/HA陶瓷是一种优良的骨组织工程支架材料，进一步优化其骨诱导作用后，有可能直接用于再生和重建负重骨干的缺损；2、在目前情况下，以双相多孔TCP/HA陶瓷为支架，通过体内非骨位置培养骨组织细胞形成活体骨修复器件，有可能用于负重骨干缺损的再生和重建。

Several regenerative procedures have been used for intra-bony defects including guided tissue regeneration, autografts, allografts, alloplasts, and combination of these techniques. These procedures have been reported to show different degrees of success.

目前常用的再生治疗方法有植骨术、引导性组织再生术（guided tissue regeneration，GTR）或二者的联合应用等，上述方法可以获得不同程度的成功率，但组织再生程度有限。

After repairing skull defect using compound implant, X-ray examination demonstrated that space between peripheral sclerotin and compound implant was covered by high-density shadow after 4 weeks.

复合材料植入免颅骨缺损后，X射线观察术后第4周骨缺损外周骨质与复合材料之间大部分被高密度阴影充填，术后第12周骨缺损外周骨质与复合材料之间完全被高密度阴影充填；光镜观察术后第8周骨小梁大部分相连成片，术后第12周骨小梁粗大，骨髓再生。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。