骨内的

The in vivo experiments performed confirm the expectative created by the in vitro results obtained and are an indication that rhBMP-2 activated chitosan films could be a very attractive biomaterial for the enhancement of osseointegration of surgical prostheses and implants and for the purpose of tissue engineering bone regeneration.

整体实验证实预期的结果，在试管内创造的结果；是一个适应症，rhBMP-2活化壳聚糖薄膜可以是一个非常吸引人的生物材料，用来义颌骨整合的增强，埋植剂，和为了组织工程古再生的目的。

All iliac hone graft fused well and a great deal of bony callus was found the vertebral body surface. Lucency area was in seen surrounding the hone graft, titanium and AC-AFF on the X-ray films, and there wan new bone formation in the interface of internal union and bone. The central region of titanium and AC-AFF became vague and new bone formation was found in the intracavitary aim of implants by CT scan. And port of the new hone transited the parietal reticulation and connected with normal ones at titanium and AC-AFF.

髂骨植骨组融合情况良好，融合界面上有较多的骨痂生成。X线摄片见植骨块、钛网、AC-AFF中空区域模糊且有骨组织生长，内植物周围无透光带存在，植骨界面上有骨桥形成；CT扫描在钛网及AC-AFF组可见内植物腔内形成的新骨通过其四壁的网眼结构与周围骨质相接，说明所有标本均达到骨性融合，但其中以AC-AFF组形成的新骨数量为多，且较为成熟。

objective the purpose of this study was to summarize our experience of the application of internal rigid fixation with miniplate to treatment of mandibular fractures.methods a retrospective analyisis of clinical data of 67 cases,who had experienced the anatomic reduction and rigid fixation by using miniplate.with the help of maxillomandibular distraction pre operation and post operation and temporary maxillomandibular fixation during operation,the fracture bones were smoothly reduced and fixed.results clinical and radiographic examination showed that all cases gained good clinical results and precise anatomic alignment of fracture postoperatively without infection,malocclusion,bone malunion or other complications.conclusion mocortical miniplate fixation of the mandible is a reliable and effective techinique providing rigid fixation and an ideal modality for the treatment of mandibular fractures.combined with maxillomandibular fixation.

对67例下颌骨骨折患者的临床资料进行回顾总结，所有患者应用小型接骨板行坚固内固定治疗。其中7例颏部骨折，12例颏旁骨折，16例颏孔区骨折，9例体部多发性骨折，5例体部粉碎性骨折；18例合并其他部位骨折。所有患者术前经临床检查和影像学检查明确骨折的位置和骨折线的数目后，分段牙弓夹板结扎、颌间弹性牵引，使移位的骨折段逐渐复位；术中经口内切开复位、细钢丝颌间结扎、小型接骨板坚固内固定；术后行临床检查和影像学复查，必要时颌间弹性牵引7～10 d。结果所有患者手术切口ⅰ期愈合，治疗效果满意；临床检查所有患者牙合关系良好、面部对称；影像学复查证实骨折线对位良好。结论经口内切开小型接骨板坚固内固定辅以颌间固定治疗下颌骨骨折效果可靠，术后并发症少，是一种理想的手术方法。

Results In the heated bone ,bone lacunae were empty ,no bone cells existed ,bone lamella was seen ,granular basophilia staining was seen in some parts of the lamella. In bone medulla , no cell existed , thrombosis occurred in some blood ,partial bone lamella disappeared.

结果 整个视野内骨陷窝空虚，无骨细胞存在，骨板尚清晰，部分骨板出现颗粒状嗜碱性染色，骨髓腔内，基本无细胞结构，血管闭塞，哈佛氏系统结构不清，部分区域骨板层状结构消失，呈一片均质的嗜伊红染色。

BACKGROUND: This is a systematic review of studies on the prevalence of osteoarthritis in the tibiofemoral joint more than 10 years after an anterior cruciate ligament injury, the radiologic classification methods used, and risk factors for development of knee osteoarthritis.

舒芬太尼在关节镜前交叉韧带重建的出院病人关节内镇痛作用的前瞻性，随机，双盲研究背景：这是一项关于前交叉韧带损伤后10年以上胫股关节骨关节炎的发病率，所用的X线分类方法以及发展为膝骨性关节炎的危险因素这三者研究的系统评价。

objective to observe the treatment effect of dated tibia fracture by ao anatomizeness armor plate and planting bone.methods to make the arc-shaped cutting on the front outboard of shank,then getting diaplasis and redress the abnormality fracture,setting ao anatomizeness armor plate on the faultage of bone and taking the alveolus of oneself plant there.results the 16 cases got rectification of fracture.all cases got concrescence and the function of broke limbs recover well.the time of getting rid of fixation average 13 months.conclusion it is a credible and effective method that treatment of dated tibia fracture by ao anatomizeness armor plate and planting bone.

目的 观察用ao解剖钢板内固定加植骨术治疗陈旧性骨折的疗效。方法在持续硬膜外麻醉下，取胫骨前外侧弧形切口，复位、纠正骨折畸形，ao解剖钢板固定骨折断端，取自体骨移植于骨折间隙或骨质缺损处。结果 16例患者骨折畸形均纠正，骨折全部愈合，患肢功能恢复良好，内固定去除时间平均为13个月。结论 ao解剖钢板内固定加植骨术治疗陈旧性胫骨骨折是一种可靠、疗效肯定的治疗方法。 ao解剖钢板；自体骨移植；胫骨陈旧性骨折

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

Functional reconstruction of resorbed alveolar ridge is common in oral and maxillofacial surgery.

牙槽嵴萎缩或缺损后的功能重建是颌面外科经常遇到的问题，骨内种植体技术的发展使得重建效果得到很大的改善。

The optimal entrance point mostly locate at the root of accessoryprocess which adjacent to the mamillary process from L1 to L4, Theadjustable range of entrance points of the 4 segments almost cover theaccessory process, But at L5, The optimal entrance point is much moreoutside away from the accessory process, just at the middle of thetransverse process and the adjustable range of entrance points islimited.

这与钉尾间距的明显变化相一致，手术时应注意调整螺钉钉尖内偏角度观察椎弓根螺钉进钉点发现内外侧螺钉进钉点与内上、外上螺钉进钉点构成接近矩形的梯形区域，最佳进钉点居于内外进钉点中部。L1到L4最佳进钉点位于副突根部靠近乳突处，随着椎体节段下降，进钉点逐渐移向外侧，L1最佳进钉点基本在副突根部骨嵴内侧缘，L2、L3最佳进钉点基本在副突根部骨嵴上，L4最佳进钉点基本在副突根部骨嵴外侧缘。L1到L4可选进钉点范围几乎均包含副突骨嵴。L5最佳进钉点则明显偏外，多数位于副突根部与横突外端连线的中内1／3。

Some bone trabeculae showed medullary cavity formation. In the control sides, the grafts were fused with tibias at 4 weeks. Some iliac crest bones degraded gradually, but the bone trabeculae of grafts also could be seen in the medullary cavity after 60 weeks.

植入髂骨的对照侧4周时移植的髂骨与周围胫骨紧密愈合，部分位于髓腔内的髂骨逐渐降解，但直到60周时仍可在部分髓腔中见到移植的髂骨骨小梁。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。