骆驼

OBJECTIVE To provide biological pharmaceutical basis for dosage forms design of harmine hydrochloride by studying its absorption kinetics in various intestinal segments of rat.

目的 研究盐酸去氢骆驼蓬碱在大鼠胃肠道各段的吸收动力学特征，为其剂型设计提供生物药剂学依据。

Harmine hydrochloride was absorbed perfectly in the duodenum, jejunum, ileum, and colon.

结论盐酸去氢骆驼蓬碱在十二指肠、空肠、回肠及结肠中均能较好地吸收。

Harmine hydrochloride was encapsulated into liposomes by active loading method.

目的 制备高包封率的盐酸去氢骆驼蓬碱脂质体。

Results As the pH value increasing, the solubility of harmine hydrochloride was decreased, while the apparent oil-water distribution coefficient was increased.

结果 随pH值的增大，盐酸去氢骆驼蓬碱的溶解度降低，表观油水分配系数增大；采用主动载药法，包封率随脂质体内外相pH梯度的减少而降低，受孵育温度的影响不大，在药脂比小于1∶5时脂质体包封率达到80%以上。

METHOD The absorption kinetics of harmine hydrochloride from duodenum, jejunum, ileum, and colon were investigated using in situ perfusion method in the rats.

方法采用大鼠在体肠循环法分别研究盐酸去氢骆驼蓬碱在大鼠十二指肠、空肠、回肠及结肠中的吸收动力学特征。

In current study, harmine, an effective alkaloid ingredient in natural product, was extracted from Peganum harmala seeds and its intravenous emulsion was prepared.

的种子中提取分离得到有效的生物碱单体成分去氢骆驼蓬碱（Harmine，Har），并将其制成静脉注射乳剂，简称静脉乳。

KEY WORDS harmine, intravenous emulsion, extract and iso- late, preparation, characteristics, particle size, stability, drug phase distribution, in vitro release, pharmacokinetics, tissue distribution, quantitative evaluation of TDDS

本文对亚微型乳剂一系列主要理化性质的研究方法进行了有益的探索；对靶向给药系统的定量评价做出了积极的尝试；为去氢骆驼蓬碱静脉注射乳剂这一新药的进一步开发研究和应用奠定了科学的基础。

Thigh-length boots embellished with finely-woven leather strips are worn by the Hausa, and provide protection while riding camels.

豪沙人穿长度及臀的靴，装饰了细致编织的皮条，这种靴在骑骆驼时也有保护作用。

The former llama herder and coca-leaf farmer received the backing of 67 per cent of the electorate.

这位曾经的骆驼牧人和古柯叶农民受到了67%选民的支持。

One day,a handsome camel gentleman was thirsty,so he burrowed a holl in the ground in hopes of finding some water,he burrowed,burrowed,burrowed...

一天，一个英俊的骆驼绅士渴了，所以他在地上挖洞希望找到些水喝，他挖呀，挖呀。。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！