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香芹酚

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Methods:To develop the HPLC method for determination of Thymol and Carvacrol ,and compare the physico-chemical property.

高效液相色谱法测定百里香酚和香芹酚的含量,比较理化性质。

In conclusion, these results suggested that PA and carvacrol were endowed with analgesic and anti-inflammatory effects.

综合以上结果显示,左手香水抽提物及香芹酚均具有镇痛及抗发炎作用。

Result:The average recovery of carvacrol and thymol were 97\^49%( RSD =1\^78) and 99\^16%( RSD =2\^05) respectively.

结果 :香芹酚和百里香酚的平均加样回收率分别为 97 4 9%和 99 1 6 %,RSD =1 78和RSD =2 0 5。

Vase-life of gerbera flowers was extended by addition of either 50 or 100mgL-1 carvacrol and either 1 or 2mgL-1 SNP from 8.3 to 16d.

非洲菊的瓶插寿命可通过添加进浓度为50或100mg/L的香芹酚或者浓度为1或2mg/L、介于8.3至16级别的SNP溶液来得到延长。

The results shown that PA (0.5, 1.0 g/kg, p.o.) and carvacrol (2, 10, 20 mg/kg) significantly decreased the acetic acid induced writhing responses and licking time in the late phase of formalin test.

实验结果显示,在镇痛实验中左手香水抽提物 0.5, 1.0 g/kg)及香芹酚(2, 10, 20, mg/kg)均可减少由醋酸所引起之扭体次数及福马林引起之后期舔足时间。

In order to understand the mechanism of anti-inflammatory effect of PA and carvacrol, the superoxide dismutase, glutahoine reductase, glutahoine peroxidase activities in liver and malondialdehyde , cyclooxygenase 2 (COX-2), tumor necrosis factor-α levels were eveluated. Also observed inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) expression and the pathological histology in λ-carrageenan induced paw edema in mice.

本研究首先以醋酸扭体试验评估左手香水抽提物及其活性成分香芹酚是否具有镇痛效果,以福马林舔足试验辨别其镇痛作用是在周边或是中枢,再以λ-角叉菜胶诱导小鼠足跖肿胀试验探讨其抗发炎作用,并分析其肝脏组织中的超氧歧化酶、麸胱甘肽还原酶、麸胱甘肽过氧化酶活性、发炎足跖组织中的脂质过氧化指标产物丙二醛、肿瘤坏死因子-α及环氧化酶-2之含量变化,观察诱导型一氧化氮合成酶及环氧化酶-2之蛋白质表现量,并将肿胀足跖做病理切片观察之,以探讨左手香水抽提物及香芹酚之抗发炎机转。

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